(Q34572168)

3 August 2017

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title

From T to B and back again: positive feedback in systemic autoimmune disease (English)

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autoimmune connective tissue disorder

3 August 2017

main subject

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Shlomchik MJ

1

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3 August 2017

Craft JE

series ordinal

2

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3 August 2017

Mamula MJ

series ordinal

3

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3 August 2017

publication date

1 November 2001

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Nature Reviews Immunology

3 August 2017

published in

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3 August 2017

volume

1

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3 August 2017

issue

2

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3 August 2017

page(s)

147-153

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Genetic dissection of systemic lupus erythematosus

3 August 2017

cites work

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Stochastic control of anti-Sm autoantibodies in MRL/Mp-lpr/lpr mice

21 January 2018

1 reference

The lupus autoantigens and the pathogenesis of systemic lupus erythematosus

21 January 2018

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Reciprocal T-B determinant spreading develops spontaneously in murine lupus: implications for pathogenesis

21 January 2018

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21 January 2018

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Self-reactivity and the expression of memory markers vary independently in MRL-Mp+/+ and MRL-Mp-lpr/lpr mice

21 January 2018

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Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice

21 January 2018

1 reference

A role for Fas in negative selection of thymocytes in vivo

21 January 2018

1 reference

Clonal analysis of the anti-DNA repertoire of murine B lymphocytes

21 January 2018

1 reference

Induction of rheumatoid antibodies in the mouse. Regulated production of autoantibody in the secondary humoral response

21 January 2018

1 reference

Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

21 January 2018

1 reference

High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire

21 January 2018

1 reference

Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis

21 January 2018

1 reference

A rheumatoid factor transgenic mouse model of autoantibody regulation

21 January 2018

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21 January 2018

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Regulation of Anti–double-stranded DNA B Cells in Nonautoimmune Mice: Localization to the T–B Interface of the Splenic Follicle

21 January 2018

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Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate

21 January 2018

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CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells

21 January 2018

1 reference

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

21 January 2018

1 reference

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

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Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

21 January 2018

1 reference

BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator

21 January 2018

1 reference

Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS

21 January 2018

1 reference

Autoantigen-specific B cell activation in Fas-deficient rheumatoid factor immunoglobulin transgenic mice

21 January 2018

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MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells

21 January 2018

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A transgenic model of autoimmune hemolytic anemia

21 January 2018

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In vivo expression of a single viral DNA-binding protein generates systemic lupus erythematosus-related autoimmunity to double-stranded DNA and histones

21 January 2018

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Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation

21 January 2018

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Genetic and structural evidence for antigen selection of anti-DNA antibodies.

21 January 2018

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Induction of anti-DNA antibody with DNA-peptide complexes.

21 January 2018

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Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus

21 January 2018

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Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus

21 January 2018

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Signals and signs for lymphocyte responses

21 January 2018

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Immune complex processing in C1q-deficient mice

21 January 2018

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A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo

21 January 2018

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Phagocytosis and clearance of apoptotic cells is mediated by MER.

21 January 2018

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Links between complement abnormalities and systemic lupus erythematosus

21 January 2018

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Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

21 January 2018

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Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African Americans

21 January 2018

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Mechanisms of antigen uptake for presentation

21 January 2018

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The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies

21 January 2018

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Post-translational protein modifications in antigen recognition and autoimmunity

21 January 2018

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Novel packages of viral and self-antigens are generated during apoptosis

21 January 2018

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CD4(+) T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens: a model to explain spontaneous T cell activation in lupus

21 January 2018

1 reference

B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events

21 January 2018

1 reference

Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain

21 January 2018

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The role of B cells in lpr/lpr-induced autoimmunity

21 January 2018

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A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus

21 January 2018

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Induction of autoreactive B cells allows priming of autoreactive T cells

21 January 2018

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Determinant spreading: lessons from animal models and human disease

21 January 2018

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Autoantibody responses and pathology regulated by B7-1 and B7-2 costimulation in MRL/lpr lupus.

21 January 2018

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The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T cell function

21 January 2018

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Efficient and selective presentation of antigen-antibody complexes by rheumatoid factor B cells

21 January 2018

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Lupus nephritis: correlation of interstitial cells with glomerular function

21 January 2018

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Sequential study of vasculitis in MRL mice.

21 January 2018

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Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes

21 January 2018

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Polygenic control of susceptibility to murine systemic lupus erythematosus

21 January 2018

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Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

21 January 2018

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The role of clonal selection and somatic mutation in autoimmunity

21 January 2018

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Genetic basis of systemic lupus erythematosus

21 January 2018

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7 January 2021

The genetics of human systemic lupus erythematosus

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7 January 2021

Epitope spreading: the role of self peptides and autoantigen processing by B lymphocytes

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7 January 2021

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

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7 January 2021

Identification of a minimal T cell epitope recognized by antinucleosome Th cells in the C-terminal region of histone H4

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7 January 2021

Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion

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7 January 2021

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

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7 January 2021

B and T cell immune response to small nuclear ribonucleoprotein particles in lupus mice: autoreactive CD4(+) T cells recognize a T cell epitope located within the RNP80 motif of the 70K protein

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7 January 2021

A critical role for complement in maintenance of self-tolerance

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7 January 2021

Isoaspartyl post-translational modification triggers autoimmune responses to self-proteins

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7 January 2021

Hyperproliferation of BXSB B cells is linked to the Yaa allele

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7 January 2021

Do B cells drive the diversification of immune responses?

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7 January 2021

B-cell epitope spreading in autoimmunity

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7 January 2021

PD-1: an inhibitory immunoreceptor involved in peripheral tolerance

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7 January 2021

The epitope spreading cascade during progression of experimental autoimmune encephalomyelitis and multiple sclerosis

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7 January 2021

Epitope dominance: evidence for reciprocal determinant spreading to glutamic acid decarboxylase in non-obese diabetic mice

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7 January 2021

Intramolecular and intermolecular spreading during the course of organ allograft rejection

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7 January 2021

Systemic lupus erythematosus

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7 January 2021

Identifiers

DOI

10.1038/35100573

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3 August 2017

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