(Q34406705)

2 August 2017

title

Mad2 inhibits the mitotic kinesin MKlp2 (English)

1 reference

DOI

10.1083/JCB.201003095

https://api.crossref.org/works/10.1083/JCB.201003095

19 November 2024

3

Hideyuki Saya

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21149564

19 November 2024

author name string

Sang Hyun Lee

series ordinal

1

1 reference

2 August 2017

Frank McCormick

series ordinal

2

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 December 2010

1 reference

2 August 2017

13 December 2010

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21149564

full work available at URL

19 November 2024

http://jcb.rupress.org/content/jcb/191/6/1069.full.pdf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21149564

http://intl.jcb.org/cgi/content/abstract/191/6/1069

19 November 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21149564

https://europepmc.org/articles/PMC3002031

19 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21149564

https://europepmc.org/articles/PMC3002031?pdf=render

19 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21149564

https://rupress.org/jcb/article-pdf/191/6/1069/1565638/jcb_201003095.pdf

19 November 2024

1 reference

10.1083/JCB.201003095

https://api.crossref.org/works/10.1083/JCB.201003095

19 November 2024

published in

Journal of Cell Biology

1 reference

2 August 2017

volume

191

1 reference

2 August 2017

issue

6

1 reference

2 August 2017

page(s)

1069-1077

1 reference

describes a project that uses

2 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3002031/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Traffic control: regulation of kinesin motors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

Chromosomal passengers: conducting cell division

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

The spindle-assembly checkpoint in space and time

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

Mad2 overexpression promotes aneuploidy and tumorigenesis in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

How do so few control so many?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

The Rab6-binding kinesin, Rab6-KIFL, is required for cytokinesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

AIR-2: An Aurora/Ipl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

Light chain-dependent regulation of Kinesin's interaction with microtubules

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002031

Cdk1 negatively regulates midzone localization of the mitotic kinesin Mklp2 and the chromosomal passenger complex

6 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201003095

Cell cycle regulation of central spindle assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201003095

K858, a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cells

21 January 2018

1 reference

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Relocation of the chromosomal passenger complex prevents mitotic checkpoint engagement at anaphase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21149564

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.201003095

1 reference

2 August 2017

1 reference

2 August 2017

1 reference