(Q34378951)

1 August 2017

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title

Mechanisms of amyloid beta protein-induced modification in ion transport systems: implications for neurodegenerative diseases (English)

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1 August 2017

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Kourie JI

1

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1 August 2017

publication date

1 June 2001

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Cellular and Molecular Neurobiology

1 August 2017

published in

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1 August 2017

volume

21

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1 August 2017

issue

3

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1 August 2017

page(s)

173-213

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Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

1 August 2017

cites work

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12 December 2020

Calcium mobilization evoked by amyloid beta-protein involves inositol 1,4,5-triphosphate production in human platelets

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12 December 2020

Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease

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12 December 2020

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

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12 December 2020

Vitamin E protects nerve cells from amyloid beta protein toxicity

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12 December 2020

Alzheimer and beta-amyloid-treated fibroblasts demonstrate a decrease in a memory-associated GTP-binding protein, Cp20

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12 December 2020

Vascular nitric oxide may lessen Alzheimer's risk.

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12 December 2020

K+ channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid beta-protein precursor genes and neuronal death in rat hippocampus

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12 December 2020

Amyloid beta protein potentiates Ca2+ influx through L-type voltage-sensitive Ca2+ channels: a possible involvement of free radicals

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12 December 2020

Ca2+ channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture.

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12 December 2020

Oxidative stress, glutamate, and neurodegenerative disorders

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12 December 2020

Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices

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12 December 2020

The Ca2+ influx induced by beta-amyloid peptide 25-35 in cultured hippocampal neurons results from network excitation

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12 December 2020

Interaction of reactive oxygen species with ion transport mechanisms.

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12 December 2020

Enhancement of outward potassium current may participate in beta-amyloid peptide-induced cortical neuronal death

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12 December 2020

C-terminal fragment of amyloid precursor protein inhibits calcium uptake into rat brain microsomes by Mg2+-Ca2+ ATPase

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12 December 2020

beta-amyloid peptides are cytotoxic to astrocytes in culture: a role for oxidative stress.

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12 December 2020

beta-Amyloid selectively augments NMDA receptor-mediated synaptic transmission in rat hippocampus.

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12 December 2020

Theoretical models of the ion channel structure of amyloid beta-protein

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12 December 2020

Basic FGF attenuates amyloid beta-peptide-induced oxidative stress, mitochondrial dysfunction, and impairment of Na+/K+-ATPase activity in hippocampal neurons

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12 December 2020

Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer disease

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12 December 2020

K+ currents of human T-lymphocytes are unaffected by Alzheimer's disease and amyloid beta protein.

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12 December 2020

Amyloid peptides are toxic via a common oxidative mechanism

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12 December 2020

Suppression of an amyloid beta peptide-mediated calcium channel response by a secreted beta-amyloid precursor protein

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12 December 2020

Effect of beta-amyloid block of the fast-inactivating K+ channel on intracellular Ca2+ and excitability in a modeled neuron

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12 December 2020

Amyloid beta peptide (25-35) inhibits Na+-dependent glutamate uptake in rat hippocampal astrocyte cultures

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12 December 2020

Amyloid beta-peptide (A beta P) potentiates a nimodipine-sensitive L-type barium conductance in N1E-115 neuroblastoma cells

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12 December 2020

K+ channel openers protect hippocampal neurons against oxidative injury and amyloid beta-peptide toxicity

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12 December 2020

Neurotoxicity of A beta amyloid protein in vitro is not altered by calcium channel blockade

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12 December 2020

beta-Amyloid peptide-induced morphological changes coincide with increased K+ and Cl- channel activity in rat cortical astrocytes

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12 December 2020

Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation

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12 December 2020

Activation of the L voltage-sensitive calcium channel by mitogen-activated protein (MAP) kinase following exposure of neuronal cells to beta-amyloid. MAP kinase mediates beta-amyloid-induced neurodegeneration

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12 December 2020

Amyloid beta-peptides inhibit Na+/K+-ATPase: tissue slices versus primary cultures

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12 December 2020

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12 December 2020

The secreted form of the Alzheimer's beta-amyloid precursor protein stimulates a membrane-associated guanylate cyclase

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12 December 2020

Inhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in microglia by a cGMP-dependent mechanism

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12 December 2020

Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner

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12 December 2020

The effect of amylin and calcitonin gene-related peptide on insulin-stimulated glucose transport in the diaphragm.

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12 December 2020

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

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12 December 2020

Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

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12 December 2020

Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder.

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12 December 2020

Displacement currents associated with the insertion of Alzheimer disease amyloid beta-peptide into planar bilayer membranes

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12 December 2020

beta-Amyloid 25-35 activates nitric oxide synthase in a neuronal clone

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12 December 2020

Hydrogen peroxide inhibits chloride channels of the sarcoplasmic reticulum of skeletal muscle

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12 December 2020

A new hypothesis for the mechanism of amyloid toxicity, based on the calcium channel activity of amyloid beta protein (A beta P) in phospholipid bilayer membranes

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12 December 2020

Effects of sulfate ions on Alzheimer beta/A4 peptide assemblies: implications for amyloid fibril-proteoglycan interactions

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12 December 2020

Calcium dependence of C-type natriuretic peptide-formed fast K(+) channel

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12 December 2020

Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal

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12 December 2020

Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides

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12 December 2020

A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide

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12 December 2020

β-Amyloid-induced calcium influx induces apoptosis in culture by oxidative stress rather than tau phosphorylation

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12 December 2020

Aggregates of a beta-amyloid peptide are required to induce calcium currents in neuron-like human teratocarcinoma cells: relation to Alzheimer's disease

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12 December 2020

Oxidant stress inhibits Na-Ca-exchange current in cardiac myocytes: mediation by sulfhydryl groups?

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12 December 2020

Stimulation of both aerobic glycolysis and Na(+)-K(+)-ATPase activity in skeletal muscle by epinephrine or amylin.

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12 December 2020

Zn2+ interaction with Alzheimer amyloid beta protein calcium channels

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12 December 2020

Cation selective channels formed by a C-terminal fragment of beta-amyloid precursor protein.

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12 December 2020

Protection against amyloid beta peptide toxicity by zinc

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12 December 2020

Channel formation in planar lipid bilayers by a neurotoxic fragment of the beta-amyloid peptide

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12 December 2020

The amyloid precursor protein fragment His 657-Lys 676 inhibits noradrenaline- and enkephaline-induced suppression of voltage sensitive calcium currents in NG108-15 hybrid cells

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12 December 2020

gamma-Secretase, evidence for multiple proteolytic activities and influence of membrane positioning of substrate on generation of amyloid beta peptides of varying length

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12 December 2020

Hydrogen peroxide mediates amyloid beta protein toxicity

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12 December 2020

Presenilins, the Endoplasmic Reticulum, and Neuronal Apoptosis in Alzheimer's Disease

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12 December 2020

Electrophysiological effects of 25-35 amyloid-beta-protein on guinea-pig lateral septal neurons

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12 December 2020

Amylin and epinephrine have no direct effect on glucose transport in isolated rat soleus muscle

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12 December 2020

Amyloid fibril formation requires a chemically discriminating nucleation event: studies of an amyloidogenic sequence from the bacterial protein OsmB

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12 December 2020

In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

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12 December 2020

Ion channel hypothesis for Alzheimer amyloid peptide neurotoxicity

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12 December 2020

Role of intercellular and intracellular communication by nitric oxide in coupling of muscarinic receptors to activation of guanylate cyclase in neuronal cells

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12 December 2020

Glutamate release from microglia via glutamate transporter is enhanced by amyloid-beta peptide

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12 December 2020

Human and rodent sequence analogs of Alzheimer's amyloid beta A4 share similar properties and can be solubilized in buffers of pH 7.4.

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12 December 2020

Modulation of A beta adhesiveness and secretase site cleavage by zinc.

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12 December 2020

Solution Structures of β Peptide and Its Constituent Fragments: Relation to Amyloid Deposition

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12 December 2020

Free radicals enhance Na+/Ca2+ exchange in ventricular myocytes

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12 December 2020

Amyloid beta proteins reduce the GABA-induced Cl- current in identified Aplysia neurons

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12 December 2020

C-terminal fragment of Alzheimer's amyloid precursor protein inhibits sodium/calcium exchanger activity in SK-N-SH cell

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12 December 2020

Amyloid beta protein-(1-42) forms calcium-permeable, Zn2+-sensitive channel

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12 December 2020

Prion peptide fragment PrP[106-126] forms distinct cation channel types.

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12 December 2020

Barium influx mediated by the cardiac sodium-calcium exchanger in transfected Chinese hamster ovary cells

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12 December 2020

Characterization of a C-type natriuretic peptide (CNP-39)-formed cation-selective channel from platypus (Ornithorhynchus anatinus) venom

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12 December 2020

Aging modulates nitric oxide synthesis and cGMP levels in hippocampus and cerebellum. Effects of amyloid beta peptide.

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12 December 2020

Membrane currents induced in Xenopus oocytes by the C-terminal fragment of the beta-amyloid precursor protein

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12 December 2020

Alzheimer amyloid abeta1-42 channels: effects of solvent, pH, and Congo Red.

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12 December 2020

High Affinity Glutamate Transporters: Regulation of Expression and Activity

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12 December 2020

Soluble beta-amyloid induction of Alzheimer's phenotype for human fibroblast K+ channels

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12 December 2020

Amyloid deposits inside myocardial fibers in transthyretin-Met30 familial amyloidotic polyneuropathy. A histological and biochemical study

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12 December 2020

Role of potassium channels in amyloid-induced cell death.

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12 December 2020

Beta-amyloid peptide blocks the fast-inactivating K+ current in rat hippocampal neurons

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12 December 2020

Na,K-ATPase mRNA levels and plaque load in Alzheimer's disease

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12 December 2020

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12 December 2020

Presenilin 1 regulates pharmacologically distinct gamma -secretase activities. Implications for the role of presenilin in gamma -secretase cleavage

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12 December 2020

Amyloid β peptides act directly on single neurons

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12 December 2020

Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein.

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12 December 2020

Caspase and calpain substrates: roles in synaptic plasticity and cell death

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12 December 2020

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

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12 December 2020

Properties of cytotoxic peptide-formed ion channels

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12 December 2020

Impairment of membrane transport and signal transduction systems by amyloidogenic proteins

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12 December 2020

Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease

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12 December 2020

X-ray diffraction analysis of brain lipid membrane structure in Alzheimer's disease and beta-amyloid peptide interactions.

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12 December 2020

Amyloid beta-peptide-induced inhibition of MTT reduction in PC12h and C1300 neuroblastoma cells: effect of nitroprusside

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12 December 2020

Amyloid beta protein increases Ca2+ currents in rat cerebellar granule neurones

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12 December 2020

Role of natriuretic peptides in ion transport mechanisms

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12 December 2020

Solution conformations and aggregational properties of synthetic amyloid beta-peptides of Alzheimer's disease. Analysis of circular dichroism spectra

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12 December 2020

Novel domain-specific actions of amyloid precursor protein on developing synapses

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12 December 2020

Synthetic mammalian C-type natriuretic peptide forms large cation channels

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12 December 2020

Neurotrophic factors protect cortical synaptic terminals against amyloid and oxidative stress-induced impairment of glucose transport, glutamate transport and mitochondrial function

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12 December 2020

Effects of ischaemia and reperfusion on calcium exchange and mechanical function in isolated rabbit myocardium.

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12 December 2020

Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases.

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12 December 2020

ALS-linked Cu/Zn-SOD mutation impairs cerebral synaptic glucose and glutamate transport and exacerbates ischemic brain injury

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12 December 2020

Molecular genetics of Alzheimer's disease.

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12 December 2020

Activation of microglial cells by PrP and beta-amyloid fragments raises intracellular calcium through L-type voltage sensitive calcium channels

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12 December 2020

beta-Amyloid Ca(2+)-channel hypothesis for neuronal death in Alzheimer disease

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12 December 2020

Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease

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12 December 2020

Amyloid beta-peptide induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells.

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12 December 2020

Human islet amyloid polypeptide at pharmacological levels inhibits insulin and phorbol ester-stimulated glucose transport in in vitro incubated human muscle strips.

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12 December 2020

Actions of neurotoxic beta-amyloid on calcium homeostasis and viability of PC12 cells are blocked by antioxidants but not by calcium channel antagonists

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12 December 2020

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

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12 December 2020

The protective effect of K+ channel openers on beta-amyloid induced cerebrovascular endothelial dysfunction.

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12 December 2020

17?-Estradiol attenuates oxidative impairment of synaptic Na+/K+-ATPase activity, glucose transport, and glutamate transport induced by amyloid ?-peptide and iron

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12 December 2020

Aβ25–35 induces rapid lysis of red blood cells: contrast with Aβ1–42 and examination of underlying mechanisms

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12 December 2020

Amyloid peptide channels: blockade by zinc and inhibition by Congo red (amyloid channel block).

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12 December 2020

Amyloid beta peptide 25-35 modulates hydrolysis of phosphoinositides by membrane phospholipase(s) C of adult brain cortex

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12 December 2020

Abnormal glutamate transport function in mutant amyloid precursor protein transgenic mice

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12 December 2020

Enhancement of (45)Ca(2+) influx and voltage-dependent Ca(2+) channel activity by beta-amyloid-(1-40) in rat cortical synaptosomes and cultured cortical neurons. Modulation by the proinflammatory cytokine interleukin-1beta

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12 December 2020

Amyloid beta protein-induced irreversible current in rat cortical neurones

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12 December 2020

Measurement of Na(+)-K+ pump current in isolated rabbit ventricular myocytes using the whole-cell voltage-clamp technique. Inhibition of the pump by oxidant stress.

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12 December 2020

Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death

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12 December 2020

Amylin and CGRP induce insulin resistance via a receptor distinct from cAMP-coupled CGRP receptor

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12 December 2020

Structure of beta-crystallite assemblies formed by Alzheimer beta-amyloid protein analogues: analysis by x-ray diffraction.

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12 December 2020

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12 December 2020

A redox O2 sensor modulates the SR Ca2+ countercurrent through voltage- and Ca(2+)-dependent Cl- channels.

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12 December 2020

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

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12 December 2020

Amyloid beta protein (1-40) forms calcium-permeable, Zn2+-sensitive channel in reconstituted lipid vesicles

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12 December 2020

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

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12 December 2020

Glutamate Transporter Alterations in Alzheimer Disease Are Possibly Associated with Abnormal APP Expression

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12 December 2020

Membrane perturbation by the neurotoxic Alzheimer amyloid fragment beta 25-35 requires aggregation and beta-sheet formation.

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12 December 2020

A beta peptides and calcium influence secretion of the amyloid protein precursor from chick sympathetic neurons in culture

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12 December 2020

Alzheimer's disease amyloid beta-protein forms Zn(2+)-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons

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12 December 2020

Molecular mechanisms of memory and the pathophysiology of Alzheimer's disease

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12 December 2020

Amylin-mediated inhibition of insulin-stimulated glucose transport in skeletal muscle

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12 December 2020

Oxidative stress and Alzheimer disease

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12 December 2020

Identifiers

DOI

10.1023/A:1010932603406

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Dimensions Publication ID

1 August 2017

1047577348

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