(Q34279143)

1 August 2017

title

Selected reaction monitoring-based proteomics: workflows, potential, pitfalls and future directions (English)

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1 August 2017

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1

Paola Picotti

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1 August 2017

2

Ruedi Aebersold

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1 August 2017

publication date

30 May 2012

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1 August 2017

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1 August 2017

volume

9

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1 August 2017

issue

6

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1 August 2017

page(s)

555-566

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Options and considerations when selecting a quantitative proteomics strategy

1 August 2017

cites work

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Protein biomarker discovery and validation: the long and uncertain path to clinical utility

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Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma

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Stable isotope labeling by amino acids in cell culture for quantitative proteomics

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Computational prediction of proteotypic peptides for quantitative proteomics

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Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise

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12 December 2020

Global analysis of protein expression in yeast

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12 December 2020

MRMer, an interactive open source and cross-platform system for data extraction and visualization of multiple reaction monitoring experiments

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12 December 2020

Differential multisite phosphorylation of the trehalose-6-phosphate synthase gene family in Arabidopsis thaliana: a mass spectrometry-based process for multiparallel peptide library phosphorylation analysis

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Characterizing the connectivity of poly-ubiquitin chains by selected reaction monitoring mass spectrometry

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MRMaid, the web-based tool for designing multiple reaction monitoring (MRM) transitions

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An integrated mass spectrometric and computational framework for the analysis of protein interaction networks

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A database of mass spectrometric assays for the yeast proteome

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A support vector machine model for the prediction of proteotypic peptides for accurate mass and time proteomics.

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12 December 2020

In-depth proteomics of ovarian cancer ascites: combining shotgun proteomics and selected reaction monitoring mass spectrometry.

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12 December 2020

Unique ion signature mass spectrometry, a deterministic method to assign peptide identity.

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12 December 2020

Increased Selectivity, Analytical Precision, and Throughput in Targeted Proteomics

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12 December 2020

Stoichiometry Determination of the MP1−p14 Complex Using a Novel and Cost-Efficient Method To Produce an Equimolar Mixture of Standard Peptides

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12 December 2020

Quantification of beta-catenin signaling components in colon cancer cell lines, tissue sections, and microdissected tumor cells using reaction monitoring mass spectrometry

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12 December 2020

Protein Standard Absolute Quantification (PSAQ) for improved investigation of staphylococcal food poisoning outbreaks

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12 December 2020

A computational approach toward label-free protein quantification using predicted peptide detectability.

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12 December 2020

Comprehensive quantitative analysis of central carbon and amino‐acid metabolism in Saccharomyces cerevisiae under multiple conditions by targeted proteomics

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12 December 2020

Comparative evaluation of current peptide production platforms used in absolute quantification in proteomics

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12 December 2020

Scoring proteomes with proteotypic peptide probes

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Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry

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An automated and multiplexed method for high throughput peptide immunoaffinity enrichment and multiple reaction monitoring mass spectrometry-based quantification of protein biomarkers

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12 December 2020

Quantitation of human glutathione S-transferases in complex matrices by liquid chromatography/tandem mass spectrometry with signature peptides

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12 December 2020

ATAQS: A computational software tool for high throughput transition optimization and validation for selected reaction monitoring mass spectrometry

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12 December 2020

Targeted data extraction of the MS/MS spectra generated by data-independent acquisition: a new concept for consistent and accurate proteome analysis

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12 December 2020

Differential secreted proteome approach in murine model for candidate biomarker discovery in colon cancer

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12 December 2020

The implications of proteolytic background for shotgun proteomics

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12 December 2020

The evolving role of mass spectrometry in cancer biomarker discovery

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12 December 2020

Targeted quantitative analysis of Streptococcus pyogenes virulence factors by multiple reaction monitoring

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12 December 2020

Combination of improved (18)O incorporation and multiple reaction monitoring: a universal strategy for absolute quantitative verification of serum candidate biomarkers of liver cancer

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12 December 2020

Use of an immunoaffinity-mass spectrometry-based approach for the quantification of protein biomarkers from serum samples of lung cancer patients

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12 December 2020

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

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12 December 2020

Quantification of thyroglobulin, a low-abundance serum protein, by immunoaffinity peptide enrichment and tandem mass spectrometry

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12 December 2020

A guide to the Proteomics Identifications Database proteomics data repository

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12 December 2020

Mass spectrometric quantitation of peptides and proteins using Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA).

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12 December 2020

Preferentially increased nitration of alpha-synuclein at tyrosine-39 in a cellular oxidative model of Parkinson's disease.

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12 December 2020

The fundamental flaws of immunoassays and potential solutions using tandem mass spectrometry

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12 December 2020

The human plasma proteome: history, character, and diagnostic prospects

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12 December 2020

Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry

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12 December 2020

Triple quadrupole mass spectrometry for direct mixture analysis and structure elucidation

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12 December 2020

Effect of Collision Energy Optimization on the Measurement of Peptides by Selected Reaction Monitoring (SRM) Mass Spectrometry

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12 December 2020

Multiple reaction monitoring cubed for protein quantification at the low nanogram/milliliter level in nondepleted human serum

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12 December 2020

Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

1 reference

12 December 2020

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor

1 reference

12 December 2020

Assay development for the determination of phosphorylation stoichiometry using multiple reaction monitoring methods with and without phosphatase treatment: application to breast cancer signaling pathways

1 reference

12 December 2020

Targeted quantitation of site-specific cysteine oxidation in endogenous proteins using a differential alkylation and multiple reaction monitoring mass spectrometry approach

1 reference

12 December 2020

Enhanced sensitivity for selected reaction monitoring mass spectrometry-based targeted proteomics using a dual stage electrodynamic ion funnel interface.

1 reference

12 December 2020

Multiple reaction monitoring of mTRAQ-labeled peptides enables absolute quantification of endogenous levels of a potential cancer marker in cancerous and normal endometrial tissues

1 reference

12 December 2020

PHOSIDA 2011: the posttranslational modification database

1 reference

12 December 2020

High-throughput generation of selected reaction-monitoring assays for proteins and proteomes

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12 December 2020

Rapid optimization of MRM-MS instrument parameters by subtle alteration of precursor and product m/z targets

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12 December 2020

Progress in miniaturization of protein arrays--a step closer to high-density nanoarrays

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12 December 2020

Expediting the development of targeted SRM assays: using data from shotgun proteomics to automate method development

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12 December 2020

Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS

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12 December 2020

Cancer genetics-guided discovery of serum biomarker signatures for diagnosis and prognosis of prostate cancer

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12 December 2020

Determination of protein stoichiometry within protein complexes using absolute quantification and multiple reaction monitoring

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12 December 2020

A novel strategy for quantitative proteomics using isotope-coded protein labels

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12 December 2020

Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks

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12 December 2020

Methods for Peptide and Protein Quantitation by Liquid Chromatography-Multiple Reaction Monitoring Mass Spectrometry

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12 December 2020

Global absolute quantification of a proteome: Challenges in the deployment of a QconCAT strategy.

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12 December 2020

Building consensus spectral libraries for peptide identification in proteomics

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12 December 2020

Synthetic peptide arrays for pathway-level protein monitoring by liquid chromatography-tandem mass spectrometry

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12 December 2020

Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution

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12 December 2020

Selected reaction monitoring for quantitative proteomics: a tutorial

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12 December 2020

Developing multiplexed assays for troponin I and interleukin-33 in plasma by peptide immunoaffinity enrichment and targeted mass spectrometry

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12 December 2020

Stable isotopic labeling in proteomics

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12 December 2020

Quantitative analysis of an aberrant glycoform of TIMP1 from colon cancer serum by L-PHA-enrichment and SISCAPA with MRM mass spectrometry

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12 December 2020

Mutant proteins as cancer-specific biomarkers

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12 December 2020

Evaluation of blood collection tubes using selected reaction monitoring MS: implications for proteomic biomarker studies

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12 December 2020

A modified "cross-talk" between histone H2B Lys-120 ubiquitination and H3 Lys-79 methylation.

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12 December 2020

Immunofluorescence and enzyme immunomicroscopy methods

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12 December 2020

Targeted label-free quantitative analysis of secretory proteins from adipocytes in response to oxidative stress

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12 December 2020

Strategic use of immunoprecipitation and LC/MS/MS for trace-level protein quantification: myosin light chain 1, a biomarker of cardiac necrosis

1 reference

12 December 2020

Quantification of C-reactive protein in the serum of patients with rheumatoid arthritis using multiple reaction monitoring mass spectrometry and 13C-labeled peptide standards

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12 December 2020

Libraries of Specific Assays Covering Whole Proteomes: From Yeast to Man

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12 December 2020

A quantitative study of the effects of chaotropic agents, surfactants, and solvents on the digestion efficiency of human plasma proteins by trypsin

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12 December 2020

Zeptosens' protein microarrays: a novel high performance microarray platform for low abundance protein analysis

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12 December 2020

Perspectives of targeted mass spectrometry for protein biomarker verification

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12 December 2020

Collision energy optimization of b- and y-ions for multiple reaction monitoring mass spectrometry

1 reference

12 December 2020

Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry

1 reference

12 December 2020

Increased throughput for low-abundance protein biomarker verification by liquid chromatography/tandem mass spectrometry

1 reference

12 December 2020

Understanding, improving and using green fluorescent proteins

1 reference

12 December 2020

Clinical quantitation of prostate-specific antigen biomarker in the low nanogram/milliliter range by conventional bore liquid chromatography-tandem mass spectrometry (multiple reaction monitoring) coupling and correlation with ELISA tests

1 reference

12 December 2020

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

1 reference

12 December 2020

Quantitative mass spectrometric multiple reaction monitoring assays for major plasma proteins

1 reference

12 December 2020

mProphet: automated data processing and statistical validation for large-scale SRM experiments

1 reference

12 December 2020

Multiple reaction monitoring as a method for identifying protein posttranslational modifications.

1 reference

12 December 2020

Targeted proteomics using selected reaction monitoring reveals the induction of specific terpene synthases in a multi-level study of methyl jasmonate-treated Norway spruce (Picea abies).

1 reference

12 December 2020

Selected ion fragmentation with a tandem quadrupole mass spectrometer

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Crossref

https://api.crossref.org/works/10.1038%2FNMETH.2015

7 January 2021

inferred from DOI database lookup

Multiple reaction monitoring in mass spectrometry/mass spectrometry for direct analysis of complex mixtures

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNMETH.2015

7 January 2021

inferred from DOI database lookup

Protein significance analysis in selected reaction monitoring (SRM) measurements

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNMETH.2015

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NMETH.2015

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Dimensions Publication ID

1 August 2017

1012911207

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