(Q34271106)

1 August 2017

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title

The contribution of mitochondria to common disorders (English)

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1 August 2017

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https://api.crossref.org/works/10.1016/J.YMGME.2003.08.009

23 March 2024

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https://api.crossref.org/works/10.1016/J.YMGME.2003.08.009

23 March 2024

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https://api.crossref.org/works/10.1016/J.YMGME.2003.08.009

23 March 2024

author name string

Gregory M. Enns

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14567954

23 March 2024

language of work or name

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1 September 2003

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full work available at URL

1 August 2017

https://api.elsevier.com/content/article/PII:S109671920300177X?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.YMGME.2003.08.009

https://api.elsevier.com/content/article/PII:S109671920300177X?httpAccept=text/plain

23 March 2024

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https://api.crossref.org/works/10.1016/J.YMGME.2003.08.009

Molecular Genetics and Metabolism

23 March 2024

published in

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1 August 2017

volume

80

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1 August 2017

issue

1-2

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1 August 2017

page(s)

11-26

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Mitochondrial defects in neurodegenerative disease

1 August 2017

cites work

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Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress

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Advanced glycation end products contribute to amyloidosis in Alzheimer disease

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Oxidative damage in Alzheimer's

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Transfer of beta-amyloid precursor protein gene using adenovirus vector causes mitochondrial abnormalities in cultured normal human muscle

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Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons

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Evidence for physiological down-regulation of brain oxidative phosphorylation in Alzheimer's disease

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Use of cytoplasmic hybrid cell lines for elucidating the role of mitochondrial dysfunction in Alzheimer's disease and Parkinson's disease

7 January 2021

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Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

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Marked changes in mitochondrial DNA deletion levels in Alzheimer brains

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Mitochondrial DNA sequence analysis of four Alzheimer's and Parkinson's disease patients.

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Point mutations of the mtDNA control region in normal and neurodegenerative human brains

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α-Synuclein in Lewy bodies

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Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases.

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Mitochondrial Polymorphisms Significantly Reduce the Risk of Parkinson Disease

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Reactive oxygen-mediated protein oxidation in aging and disease

7 January 2021

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An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

7 January 2021

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Friedreich ataxia: from GAA triplet-repeat expansion to frataxin deficiency

7 January 2021

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Deficit of in vivo mitochondrial ATP production in patients with Friedreich ataxia

7 January 2021

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Frataxin expression rescues mitochondrial dysfunctions in FRDA cells

7 January 2021

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Glutathione in blood of patients with Friedreich's ataxia.

7 January 2021

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Spinocerebellar ataxias due to mitochondrial defects

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Autism: a mitochondrial disorder?

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Mitochondrial dysfunction in patients with hypotonia, epilepsy, autism, and developmental delay: HEADD syndrome

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Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion

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Mitochondrial function in normal and diabetic beta-cells

7 January 2021

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Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

7 January 2021

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Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA

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Molecular and clinical aspects of mitochondrial diabetes mellitus

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Peripheral blood mitochondrial DNA content is inversely correlated with insulin secretion during hyperglycemic clamp studies in healthy young men.

7 January 2021

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Increased expression of mitochondrial-encoded genes in skeletal muscle of humans with diabetes mellitus

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Oxidative DNA damage in diabetes mellitus: its association with diabetic complications

7 January 2021

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Oxidative damage to mitochondrial DNA and its relationship to diabetic complications

7 January 2021

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Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell

7 January 2021

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Glucokinase as pancreatic beta cell glucose sensor and diabetes gene

7 January 2021

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Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells

7 January 2021

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7 January 2021

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Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line, MIN6.

7 January 2021

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Ca(2+)- and GTP-dependent exocytosis in mouse pancreatic beta-cells involves both common and distinct steps.

7 January 2021

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Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis.

7 January 2021

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Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

7 January 2021

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Glutamate is not a messenger in insulin secretion

7 January 2021

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Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene

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Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

7 January 2021

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Diabetes, oxidative stress, and antioxidants: a review

7 January 2021

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Glucose Down-regulates the Expression of the Peroxisome Proliferator-activated Receptor-α Gene in the Pancreatic β-Cell

7 January 2021

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beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors

7 January 2021

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Molecular targets of a human HNF1 alpha mutation responsible for pancreatic beta-cell dysfunction

7 January 2021

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Glutamine:fructose-6-phosphate aminotransferase enzyme activity is necessary for the induction of TGF-beta1 and fibronectin expression in mesangial cells

7 January 2021

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High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells

7 January 2021

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Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

7 January 2021

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Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

7 January 2021

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Identification of the mechanism for the inhibition of Na+,K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2

7 January 2021

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Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response

7 January 2021

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Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.

7 January 2021

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Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?

7 January 2021

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Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

7 January 2021

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Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

7 January 2021

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The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway

7 January 2021

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Mutations in SDHC cause autosomal dominant paraganglioma, type 3.

7 January 2021

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Germ-line mutations in nonsyndromic pheochromocytoma

7 January 2021

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Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

7 January 2021

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A role for mitochondrial enzymes in inherited neoplasia and beyond

7 January 2021

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The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid

7 January 2021

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N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells

7 January 2021

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N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro

7 January 2021

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Prevention of PC12 Cell Death byN-Acetylcysteine Requires Activation of the Ras Pathway

7 January 2021

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Reduction of lower motor neuron degeneration in wobbler mice by N-acetyl-L-cysteine

7 January 2021

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Therapeutic potential of N-acetylcysteine in age-related mitochondrial neurodegenerative diseases

7 January 2021

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The pharmacokinetics and pharmaco-dynamics of Procysteine in amyotrophic lateral sclerosis

7 January 2021

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Assessment of DNA base oxidation and glutathione level in patients with type 2 diabetes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.08.009

Effect of oxidative stress on glutathione pathway in red blood cells from patients with insulin-dependent diabetes mellitus

7 January 2021

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Insulin and glucagon regulation of glutathione S-transferase expression in primary cultured rat hepatocytes

7 January 2021

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Effects of alpha lipoic acid, ascorbic acid-6-palmitate, and fish oil on the glutathione, malonaldehyde, and fatty acids levels in erythrocytes of streptozotocin induced diabetic male rats

7 January 2021

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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

7 January 2021

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Sequential inactivation of reactive oxygen species by combined overexpression of SOD isoforms and catalase in insulin-producing cells

7 January 2021

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Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts

7 January 2021

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Impaired ascorbic acid metabolism in streptozotocin-induced diabetic rats

7 January 2021

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Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus

7 January 2021

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Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators

7 January 2021

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Glucose-induced changes in protein kinase C and nitric oxide are prevented by vitamin E

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.08.009

Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.08.009

Could coenzyme Q10 and L-carnitine be a treatment for diabetes secondary to 3243 mutation of mtDNA?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.08.009

A case of diabetic amyotrophy associated with 3243 mitochondrial tRNA(leu; UUR) mutation and successful therapy with coenzyme Q10

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.08.009

Diabetes mellitus associated with 3243 mitochondrial tRNALeu(UUR) mutation: Clinical features and coenzyme Q10 treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.08.009

The effects of coenzyme Q10 treatment on maternally inherited diabetes mellitus and deafness, and mitochondrial DNA 3243 (A to G) mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.08.009

Correction of pancreatic beta-cell dysfunction with coenzyme Q(10) in a patient with mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes syndrome and diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.08.009

Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.08.009

High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy. A randomized double-blind comparison

7 January 2021

1 reference

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Protective actions of YM737, a new glutathione analog, against cerebral ischemia in rats

7 January 2021

series ordinal

134

1 reference

https://api.crossref.org/works/10.1016/J.YMGME.2003.08.009

23 March 2024

Identifiers

1 reference

1 August 2017

1 reference