(Q34214364)

31 July 2017

title

Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo (English)

1 reference

31 July 2017

Dongtao Ni Li

1

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31 July 2017

Stephen P Matthews

2

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31 July 2017

Antony N Antoniou

3

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31 July 2017

Daniela Mazzeo

4

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31 July 2017

Colin Watts

5

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31 July 2017

language of work or name

English

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publication date

14 July 2003

1 reference

Journal of Biological Chemistry

31 July 2017

number of pages

11

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based on heuristic

inferred from page(s)

published in

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31 July 2017

volume

278

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31 July 2017

issue

40

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31 July 2017

page(s)

38980-38990

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Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase

31 July 2017

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Molecular characterization of a vacuolar processing enzyme related to a putative cysteine proteinase of Schistosoma mansoni

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Primary structures of Sm31/32 diagnostic proteins of Schistosoma mansoni and their identification as proteases

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Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

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An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.

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Control of antigen presentation by a single protease cleavage site

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Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP.

21 January 2018

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Cathepsin S and an asparagine-specific endoprotease dominate the proteolytic processing of human myelin basic protein in vitro

21 January 2018

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A closer look at proteolysis and MHC-class-II-restricted antigen presentation.

21 January 2018

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Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone.

21 January 2018

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Activation of progelatinase A by mammalian legumain, a recently discovered cysteine proteinase

21 January 2018

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Prothymosin alpha is processed to thymosin alpha 1 and thymosin alpha 11 by a lysosomal asparaginyl endopeptidase

21 January 2018

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Identification of human asparaginyl endopeptidase (legumain) as an inhibitor of osteoclast formation and bone resorption

21 January 2018

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Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice

21 January 2018

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Activation of Arabidopsis vacuolar processing enzyme by self-catalytic removal of an auto-inhibitory domain of the C-terminal propeptide

21 January 2018

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Identification of a cDNA encoding an active asparaginyl endopeptidase of Schistosoma mansoni and its expression in Pichia pastoris

21 January 2018

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Autocatalytic activation of human legumain at aspartic acid residues

21 January 2018

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Activation of human prolegumain by cleavage at a C-terminal asparagine residue

21 January 2018

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High Levels of Recombinant CYP3A4 Expression in Chinese Hamster Ovary Cells Are Modulated by Coexpressed Human P450 Reductase and Hemin Supplementation

21 January 2018

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

21 January 2018

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Gene amplification and drug resistance in cultured murine cells.

21 January 2018

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Direct demonstration of binding of a lysosomal enzyme, alpha-L-iduronidase, to receptors on cultured fibroblasts

21 January 2018

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Autocatalytic processing of recombinant human procathepsin L. Contribution of both intermolecular and unimolecular events in the processing of procathepsin L in vitro

21 January 2018

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Autocatalytic processing of recombinant human procathepsin B is a bimolecular process

21 January 2018

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Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells.

21 January 2018

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Multiple functional proteins are produced by cleaving Asn-Gln bonds of a single precursor by vacuolar processing enzyme

21 January 2018

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Substrate specificity of schistosome versus human legumain determined by P1-P3 peptide libraries

21 January 2018

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Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion

21 January 2018

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Crystal structure of the wild-type human procathepsin B at 2.5 Å resolution reveals the native active site of a papain-like cysteine protease zymogen

21 January 2018

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The crystal structure of human procathepsin K

21 January 2018

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Mammalian caspases: structure, activation, substrates, and functions during apoptosis

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A unified model for apical caspase activation

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Regulation of human separase by securin binding and autocleavage

21 January 2018

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Sequential autolytic processing activates the zymogen of Arg-gingipain

21 January 2018

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The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli

21 January 2018

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Activation of lysosomal function during dendritic cell maturation

21 January 2018

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Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells

21 January 2018

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MHC Class II Expression Is Regulated in Dendritic Cells Independently of Invariant Chain Degradation

21 January 2018

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Antigen-specific interaction between T and B cells

21 January 2018

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The two cysteine endopeptidases of legume seeds: purification and characterization by use of specific fluorometric assays

21 January 2018

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Asparaginyl endopeptidase activity in adult Schistosoma mansoni

21 January 2018

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Processing creates the self

21 January 2018

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Vacuolar processing enzyme is self-catalytically activated by sequential removal of the C-terminal and N-terminal propeptides

21 January 2018

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Colorimetric and fluorimetric microplate assays for legumain and a staining reaction for detection of the enzyme after electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305930200

Identification of internal autoproteolytic cleavage sites within the prosegments of recombinant procathepsin B and procathepsin S. Contribution of a plausible unimolecular autoproteolytic event for the processing of zymogens belonging to the papain

21 January 2018

1 reference

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Pig kidney legumain: an asparaginyl endopeptidase with restricted specificity.

21 January 2018

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Transport of peptide-MHC class II complexes in developing dendritic cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M305930200

1 reference

31 July 2017

1 reference