(Q34185013)

31 July 2017

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title

Pharmacokinetics and pharmacodynamics of cannabinoids (English)

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31 July 2017

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Franjo Grotenhermen

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31 July 2017

publication date

1 January 2003

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Clinical Pharmacokinetics

31 July 2017

published in

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31 July 2017

volume

42

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31 July 2017

issue

4

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31 July 2017

page(s)

327-360

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Cannabidiol, a non-psychoactive component of cannabis and its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats

31 July 2017

cites work

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12 December 2020

Neuropsychological performance in long-term cannabis users

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12 December 2020

Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs

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12 December 2020

Endocannabinoids and fatty acid amides in cancer, inflammation and related disorders

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12 December 2020

Comparison of effects of marihuana cigarettes of three different potencies

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12 December 2020

(R)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability

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12 December 2020

Urinary excretion half-life of 11-nor-9-carboxy-delta9-tetrahydrocannabinol in humans

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12 December 2020

Blood cannabinoids. II. Models for the prediction of time of marijuana exposure from plasma concentrations of delta 9-tetrahydrocannabinol (THC) and 11-nor-9-carboxy-delta 9-tetrahydrocannabinol (THCCOOH)

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12 December 2020

Cannabis, cognition, and residual confounding

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12 December 2020

Identification of (-)-delta 9-6a,10a-trans-tetrahydrocannabinol and two of its metabolites in rats by use of combination gas chromatography-mass spectrometry and mass fragmentography

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12 December 2020

Interaction between delta-9-tetrahydrocannabinol and indomethacin

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12 December 2020

Actions of cannabis constituents on enzymes of arachidonate metabolism: anti-inflammatory potential

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12 December 2020

A major metabolite of delta 1-tetrahydrocannabinol reduces its cataleptic effect in mice

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12 December 2020

Anti-edema and analgesic properties of delta9-tetrahydrocannabinol (THC)

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12 December 2020

Antibacterial activity of Δ9-tetrahydrocannabinol and cannabidiol

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12 December 2020

3H-delta9-tetrahydrocannabinol distribution in pregnant dogs and their fetuses

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12 December 2020

Cannabinoid compounds in South African Cannabis sativa L

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12 December 2020

Tetrahydrocannabinol for tremor in multiple sclerosis

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12 December 2020

A comparison of the ocular and central effects of delta 9-tetrahydrocannabinol and cannabigerol

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12 December 2020

'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance.

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12 December 2020

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

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12 December 2020

Effect of cannabidiol pretreatment on the kinetics of tetrahydrocannabinol metabolites in mouse brain.

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12 December 2020

Identification in human urine of delta 9-tetrahydrocannabinol-11-oic acid glucuronide: a tetrahydrocannabinol metabolite.

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12 December 2020

Effects of smoking marijuana on brain perfusion and cognition.

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12 December 2020

Bidirectional control of airway responsiveness by endogenous cannabinoids

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12 December 2020

Control of the cell survival/death decision by cannabinoids

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12 December 2020

Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS.

1 reference

12 December 2020

Cytochrome P-450 isozymes involved in the oxidative metabolism of delta 9-tetrahydrocannabinol by liver microsomes of adult female rats

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12 December 2020

Pharmacology of cannabinoid CB1 and CB2 receptors.

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12 December 2020

Cannabinoid inhibition of capsaicin-sensitive sensory neurotransmission in the rat mesenteric arterial bed.

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12 December 2020

Concentration-effect relationship of delta-9-tetrahydrocannabiol and prediction of psychotropic effects after smoking marijuana

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12 December 2020

Cannabis: pharmacology and toxicology in animals and humans

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12 December 2020

The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain

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12 December 2020

The effect of orally and rectally administered delta 9-tetrahydrocannabinol on spasticity: a pilot study with 2 patients

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12 December 2020

The tetrahydrocannabinol and tetrahydrocannabinolic acid content of cannabis products

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12 December 2020

Enhancement of brain [3H]flunitrazepam binding and analgesic activity of synthetic cannabimimetics

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12 December 2020

Mechanisms of endocannabinoid inactivation: biochemistry and pharmacology.

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12 December 2020

Pharmacological evaluation of aerosolized cannabinoids in mice

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12 December 2020

Bronchodilator effect of delta1-tetrahydrocannabinol

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12 December 2020

Self-catalyzed inactivation of cytochrome P-450 during microsomal metabolism of cannabidiol

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12 December 2020

11-hydroxy- 9 -tetrahydrocannabinol: pharmacology, disposition, and metabolism of a major metabolite of marihuana in man.

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12 December 2020

The effects of cannabinoids on the pharmacokinetics of indinavir and nelfinavir

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12 December 2020

Open label evaluation of cannabidiol in dystonic movement disorders

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12 December 2020

Functional role for cannabinoids in respiratory stability during sleep

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12 December 2020

Comparison of acute oral toxicity of cannabinoids in rats, dogs and monkeys

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12 December 2020

GC/MS and EMIT analyses for delta 9-tetrahydrocannabinol metabolites in plasma and urine of human subjects

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12 December 2020

The Metabolism of Δ9-Tetrahydrocannabinol and Related Cannabinoids in Man

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12 December 2020

Marijuana effect and delta-9-tetrahydrocannabinol plasma level

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12 December 2020

Complex pharmacology of natural cannabinoids: evidence for partial agonist activity of delta9-tetrahydrocannabinol and antagonist activity of cannabidiol on rat brain cannabinoid receptors

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12 December 2020

Cannabinoid pharmacology

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12 December 2020

Plasma and brain levels of delta 6-THC and seven monooxygenated metabolites correlated to the cataleptic effect in the mouse

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12 December 2020

Binding of (+)- and (minus)-delta-1-tetrahydrocannabinols and (minus)-7-hydroxy-delta-1-tetrahydrocannabinol to blood cells and plasma proteins in man

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12 December 2020

Observational analysis of feeding induced by Delta9-THC and anandamide

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12 December 2020

Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response

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12 December 2020

Effects of tetrahydrocannabinol on melatonin secretion in man.

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12 December 2020

Cannabinoids inhibit pre- and postjunctionally sympathetic neurotransmission in rat mesenteric arteries.

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12 December 2020

Analgesic Effect of Delta‐9‐Tetrahydrocannabinol

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12 December 2020

Effects of cannabinoids (marijuana) on taste intensity and hedonic ratings and salivary flow of adults

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12 December 2020

Characterization of the lipophilicity of natural and synthetic analogs of delta 9-tetrahydrocannabinol and its relationship to pharmacological potency.

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12 December 2020

Enhancement of Anandamide Formation in the Limbic Forebrain and Reduction of Endocannabinoid Contents in the Striatum of Δ9-Tetrahydrocannabinol-Tolerant Rats

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12 December 2020

Cannabinoids decrease the K(+) M-current in hippocampal CA1 neurons.

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12 December 2020

Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease

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12 December 2020

Stability, transfer and absorption of cannabinoid constituents of cannabis (hashish) during smoking

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12 December 2020

Antagonism of marihuana effects by indomethacin in humans

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12 December 2020

Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation

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12 December 2020

Pharmacology of cannabinoid receptor ligands.

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12 December 2020

Behavioral and biochemical effects of chronic ? 9-tetrahydrocannabinol in rats

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12 December 2020

Time course for the induction and maintenance of tolerance to Delta(9)-tetrahydrocannabinol in mice

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12 December 2020

Antiemetic efficacy of levonantradol compared to delta-9-tetrahydrocannabinol for chemotherapy-induced nausea and vomiting.

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12 December 2020

Effects of marihuana on sleeping states

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12 December 2020

Determination and characterization of a cannabinoid receptor in rat brain

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12 December 2020

Central and peripheral cannabinoid modulation of gastrointestinal transit in physiological states or during the diarrhoea induced by croton oil.

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12 December 2020

Ocular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol

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12 December 2020

Topical Δ9-tetrahydrocannabinol in hypertensive glaucomas

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12 December 2020

Cytoskeletal organization following cannabinoid treatment in undifferentiated and differentiated PC12 cells

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12 December 2020

Changes in human spermatozoa associated with high dose marihuana smoking

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12 December 2020

Triggering myocardial infarction by marijuana

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12 December 2020

Comparison of the subjective effects of Delta(9)-tetrahydrocannabinol and marijuana in humans.

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12 December 2020

Tobacco and cannabis smoking cessation can lead to intoxication with clozapine or olanzapine

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12 December 2020

Endocannabinoids control spasticity in a multiple sclerosis model

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12 December 2020

Clinical pharmacokinetics of escalating i.v. doses of dexanabinol (HU-211), a neuroprotectant agent, in normal volunteers

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12 December 2020

Determination of delta 1-tetrahydrocannabinol in human fat biopsies from marihuana users by gas chromatography-mass spectrometry

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12 December 2020

Whole-body autoradiography of 1-tetrahydrocannabinol and 1(6)-tetrahydrocannabinol in mouse. Pharmacokinetic aspects of 1-tetrahydrocannabinol and its metabolites

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12 December 2020

Distribution of marihuana in monkey brain and concomitant behavioural effects

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12 December 2020

Performance-based testing for drugs of abuse: dose and time profiles of marijuana, amphetamine, alcohol, and diazepam

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12 December 2020

Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors

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12 December 2020

Pharmacokinetics of nabilone, a psychotropically active 9-ketocannabinoid, in the dog. Utilization of quantitative selected ion monitoring and deuterium labeling

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12 December 2020

Recent clinical experience with dronabinol

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12 December 2020

Cannabinoid agonists inhibit the activation of 5-HT3 receptors in rat nodose ganglion neurons

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12 December 2020

Long-retained metabolites of delta9- and delta8-tetrahydrocannabinols identified as novel fatty acid conjugates

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12 December 2020

Nabilone in the treatment of multiple sclerosis.

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12 December 2020

Distribution of tritiated-1 delta 9tetrahydrocannabinol in rat tissues after inhalation

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12 December 2020

Pharmacokinetics and metabolism of delta 1-tetrahydrocannabinol and other cannabinoids with emphasis on man.

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12 December 2020

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial

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12 December 2020

Abuse potential of dronabinol (Marinol).

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12 December 2020

Long-term efficacy and safety of dronabinol for acquired immunodeficiency syndrome-associated anorexia

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12 December 2020

Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapy-induced nausea and vomiting

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12 December 2020

Metabolic studies of delta-9-tetrahydrocannabinol in cancer patients

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12 December 2020

Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.

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12 December 2020

Species specificity in the metabolism of nabilone. Relationship between toxicity and metabolic routes

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12 December 2020

Loss of cannabinoid-stimulated guanosine 5'-O-(3-[(35)S]Thiotriphosphate) binding without receptor down-regulation in brain regions of anandamide-tolerant rats

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12 December 2020

Effects of chronic exposure to delta9-tetrahydrocannabinol on cannabinoid receptor binding and mRNA levels in several rat brain regions

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12 December 2020

Cannabinoid CB(1) receptor upregulation in a rat model of chronic neuropathic pain

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12 December 2020

Cannabinoids, hippocampal function and memory

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12 December 2020

Effective treatment of Tourette's syndrome with marijuana.

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12 December 2020

Cannabis substitution. An adjunctive therapeutic tool in the treatment of alcoholism

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12 December 2020

Motor actions of cannabinoids in the basal ganglia output nuclei

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12 December 2020

Blood cannabinoids. I. Absorption of THC and formation of 11-OH-THC and THCCOOH during and after smoking marijuana

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12 December 2020

Delta-9-Tetrahydrocannabinol: Localization in Body Fat

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12 December 2020

Stability of 9-Tetrahydrocannabinol (THC), 11-Hydroxy-THC, and 11-Nor-9-carboxy-THC in Blood and Plasma

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12 December 2020

The use of cannabis as a mood stabilizer in bipolar disorder: anecdotal evidence and the need for clinical research

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12 December 2020

Psychoactive cannabinoids reduce gastrointestinal propulsion and motility in rodents.

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12 December 2020

The cannabinoids as potential antiepileptics

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12 December 2020

Stereochemical effects of 11-OH-delta 8-THC-dimethylheptyl in mice and dogs

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12 December 2020

Brain levels of 1 -tetrahydrocannabinol and its metabolites in mice--correlation with behaviour, and the effect of the metabolic inhibitors SKF 525A and piperonyl butoxide

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12 December 2020

Effects of Dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease

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12 December 2020

Rectal bioavailability of delta-9-tetrahydrocannabinol from the hemisuccinate ester in monkeys

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12 December 2020

The cannabinoid acids: nonpsychoactive derivatives with therapeutic potential

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12 December 2020

The stability of cannabis and its preparations on storage

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12 December 2020

Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects

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12 December 2020

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

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12 December 2020

Pain modulation by release of the endogenous cannabinoid anandamide

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12 December 2020

Effect of repeated administration of 11-hydroxy-delta 8-tetrahydrocannabinol, an active metabolite of delta 8-tetrahydrocannabinol, on the hepatic microsomal drug-metabolizing enzyme system of mice

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12 December 2020

Binding of δ1-tetrahydrocannabinol to human plasma proteins

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12 December 2020

Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands.

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12 December 2020

Delta-9-tetrahydrocannabinol delays the gastric emptying of solid food in humans: a double-blind, randomized study

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12 December 2020

[Psychotropic drugs. II. Determination of cannabinoids in Cannabis sativa L. and in cannabis products with high pressure liquid chromatography (HPLC)]

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12 December 2020

Temporal indication of marijuana use can be estimated from plasma and urine concentrations of delta9-tetrahydrocannabinol, 11-hydroxy-delta9-tetrahydrocannabinol, and 11-nor-delta9-tetrahydrocannabinol-9-carboxylic acid

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12 December 2020

Physiologic disposition of nabilone, a cannabinol derivative, in man

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12 December 2020

Metabolites of cannabidiol identified in human urine

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12 December 2020

Cognitive functioning of long-term heavy cannabis users seeking treatment

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12 December 2020

2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain

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12 December 2020

Assessment of Tolerance to Immunosuppressive Activity of Δ9-Tetrahydrocannabinoll in Rats

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12 December 2020

Leptin-regulated endocannabinoids are involved in maintaining food intake

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12 December 2020

Nabilone increases choreatic movements in Huntington's disease

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12 December 2020

Urinary metabolites of delta 1-tetrahydrocannabinol in man

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12 December 2020

Elevated endogenous cannabinoids in schizophrenia

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12 December 2020

Evidence that cannabidiol does not significantly alter the pharmacokinetics of tetrahydrocannabinol in man

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12 December 2020

Functional Role of High-Affinity Anandamide Transport, as Revealed by Selective Inhibition

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12 December 2020

Evidence for a cannabinoid receptor in sea urchin sperm and its role in blockade of the acrosome reaction

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12 December 2020

[Results of a standardized survey on the medical use of cannabis products in the German-speaking area].

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12 December 2020

Induction and genetic regulation of mouse hepatic cytochrome P450 by cannabidiol

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12 December 2020

Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide

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12 December 2020

Clinical studies of cannabis tolerance and dependence

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12 December 2020

Chronic cannabinoid, CP-55,940, administration alters biotransformation in the rat.

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12 December 2020

Cardiovascular effects of prolonged delta-9-tetrahydrocannabinol ingestion

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12 December 2020

Treatment of Tourette's syndrome with delta-9-tetrahydrocannabinol

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12 December 2020

Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac

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12 December 2020

Characterization of the butyl homologues of Δ1-tetrahydrocannabinol, cannabinol and cannabidiol in samples of cannabis by combined gas chromatography and mass spectrometry

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12 December 2020

Randomised, double-blind, placebo-controlled trial to assess the potential of cannabinoid receptor stimulation in the treatment of dystonia

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12 December 2020

Metabolism of delta 9-tetrahydrocannabinol by cytochrome P450 isozymes purified from hepatic microsomes of monkeys

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12 December 2020

Determination of delta 9-tetrahydrocannabinol levels in brain tissue using high-performance liquid chromatography with electrochemical detection

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12 December 2020

Effects of delta-9-tetrahydrocannabinol on delayed match to sample performance in rats: alterations in short-term memory associated with changes in task specific firing of hippocampal cells

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12 December 2020

Further studies on the antinociceptive effects of delta 6-THC-7-oic acid

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12 December 2020

Comparison of 3H- and 125I-Radioimmunoassay and Gas Chromatography/Mass Spectrometry for the Determination of 9-Tetrahydrocannabinol and Cannabinoids in Blood and Serum

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12 December 2020

Potency trends of delta9-THC and other cannabinoids in confiscated marijuana from 1980-1997.

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12 December 2020

Tetrahydrocannabinol for treatment of chronic pain

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12 December 2020

Metabolism of tetrahydrocannabinol in frequent and infrequent marijuana users

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12 December 2020

Health aspects of cannabis

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12 December 2020

Metabolism of delta 9 -tetrahydrocannabinol by lung and liver homogenates of rats treated with methylcholanthrene

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12 December 2020

On the metabolism of tritium-labelled Δ1-tetrahydrocannabinol in the rabbit

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12 December 2020

Recent advances in the metabolism of cannabinoids

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12 December 2020

Delta-9-Tetrahydrocannabinol: Metabolism and Disposition in Long-Term Marihuana Smokers

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12 December 2020

In vitro metabolism of tetrahydrocannabinol by rhesus monkey liver and human liver

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12 December 2020

Plasma delta-9-tetrahydrocannabinol concentrations and clinical effects after oral and intravenous administration and smoking

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12 December 2020

Cannabidiol interferes with the effects of Δ9-tetrahydrocannabinol in man

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12 December 2020

Improvement of memory in rodents by the selective CB1 cannabinoid receptor antagonist, SR 141716.

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12 December 2020

Comparative in vitro metabolism of the cannabinoids

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12 December 2020

Randomised clinical trial of levonantradol and chlorpromazine in the prevention of radiotherapy-induced vomiting

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12 December 2020

Excretion patterns of cannabinoid metabolites after last use in a group of chronic users

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12 December 2020

Nicotine and cannabinoids as adjuncts to neuroleptics in the treatment of Tourette syndrome and other motor disorders

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12 December 2020

The analgesic properties of delta-9-tetrahydrocannabinol and codeine

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12 December 2020

Differential effects on cognitive functioning in 9- to 12-year olds prenatally exposed to cigarettes and marihuana

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12 December 2020

Relationship between plasma delta-9-tetrahydrocannabinol concentration and pharmacologic effects in man

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12 December 2020

Blockade of effects of smoked marijuana by the CB1-selective cannabinoid receptor antagonist SR141716.

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12 December 2020

Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation

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12 December 2020

Fetal disposition of delta 9-tetrahydrocannabinol (THC) during late pregnancy in the rhesus monkey

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12 December 2020

Marijuana for intractable hiccups

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12 December 2020

Fate of 14C-delta1-THC in rat plasma after intravenous injection and smoking.

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12 December 2020

Metabolism of Δ1-tetrahydrocannabinol by the isolated perfused dog lung. Comparison with in vitro liver metabolism

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12 December 2020

Development of behavioral tolerance to delta 9-THC without alteration of cannabinoid receptor binding or mRNA levels in whole brain

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12 December 2020

Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat.

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12 December 2020

The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation.

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12 December 2020

Effect of marihuana on intraocular and blood pressure in glaucoma.

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12 December 2020

Clinical effects and plasma levels of ?9-Tetrahydrocannabinol (?9-THC) in heavy and light users of cannabis

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12 December 2020

Pharmacokinetics, metabolism and drug-abuse potential of nabilone

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12 December 2020

Gastric antisecretory role and immunohistochemical localization of cannabinoid receptors in the rat stomach

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12 December 2020

The safety and pharmacokinetics of single-agent and combination therapy with megestrol acetate and dronabinol for the treatment of HIV wasting syndrome. The DATRI 004 Study Group. Division of AIDS Treatment Research Initiative

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12 December 2020

Metabolism, disposition, and kinetics of delta-9-tetrahydrocannabinol in men and women

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12 December 2020

Some features of Cannabis plants grown in the United Kingdom from seeds of known origin

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12 December 2020

Characterization of cytochrome P450 3A inactivation by cannabidiol: possible involvement of cannabidiol-hydroxyquinone as a P450 inactivator

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12 December 2020

Alcohol and marijuana: effects on epilepsy and use by patients with epilepsy

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12 December 2020

Human Placental Transfer of Cannabinoids

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12 December 2020

Delta-9-THC in the treatment of spasticity associated with multiple sclerosis

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12 December 2020

Synergistic interactions of endogenous opioids and cannabinoid systems

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12 December 2020

Stereospecific effects of (-)- and (+)-7-hydroxy-delta-6-tetrahydrocannabinol-dimethylheptyl on the immune system of mice

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12 December 2020

Dronabinol versus megestrol acetate versus combination therapy for cancer-associated anorexia: a North Central Cancer Treatment Group study

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12 December 2020

Different cannabinoids exhibit different pharmacological and toxicological properties

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12 December 2020

Receptor-independent effects of natural cannabinoids in rat peritoneal mast cells in vitro

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12 December 2020

Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations

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12 December 2020

Hu 210: a potent tool for investigations of the cannabinoid system.

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12 December 2020

Biphasic Effects of Anandamide

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12 December 2020

Marihuana Smoking and Intraocular Pressure

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12 December 2020

Evaluation of intramuscular levonantradol and placebo in acute postoperative pain

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12 December 2020

Biological aspects of cannabis use

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12 December 2020

Delta-9-tetrahydrocannabinol differentially suppresses cisplatin-induced emesis and indices of motor function via cannabinoid CB(1) receptors in the least shrew

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12 December 2020

Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain

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12 December 2020

Presence of Δ9-Tetrahydrocannabinol in Human Milk

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12 December 2020

Antitumor effects of ajulemic acid (CT3), a synthetic non-psychoactive cannabinoid

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12 December 2020

Short-Term Effects of Smoked Marihuana on Left Ventricular Function in Man

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12 December 2020

The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation

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12 December 2020

Effects of tetrahydrocannabinol on arterial and intraocular hypertension

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12 December 2020

Profiles of delta 9-tetrahydrocannabinol metabolites in urine of marijuana users: preliminary observations by high performance liquid chromatography-radioimmunoassay

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12 December 2020

Suppressive Effect of -9-Tetrahydrocannabinol on Herpes Simplex Virus Infectivity In Vitro

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12 December 2020

Antiemetics in patients receiving chemotherapy for cancer: a randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine

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12 December 2020

Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot study

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12 December 2020

The role of the placenta in variability of fetal exposure to cocaine and cannabinoids: a twin study

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12 December 2020

Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors augments cAMP accumulation in striatal neurons: evidence for a Gs linkage to the CB1 receptor.

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12 December 2020

Involvement of CYP2C in the metabolism of cannabinoids by human hepatic microsomes from an old woman

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12 December 2020

Interactions of delta 1-tetrahydrocannabinol with cannabinol and cannabidiol following oral administration in man. Assay of cannabinol and cannabidiol by mass fragmentography

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12 December 2020

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

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12 December 2020

Observations on the effects of four weeks of heavy marihuana smoking on group interaction and individual behavior

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12 December 2020

Antagonism to the actions of platelet activating factor by a nonpsychoactive cannabinoid

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12 December 2020

Acute cardiovascular fatalities following cannabis use.

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12 December 2020

Physiochemical properties, solubility, and protein binding of delta9-tetrahydrocannabinol

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12 December 2020

Structure-activity relationships in cannabinoids

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12 December 2020

Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors.

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12 December 2020

Delta-9-tetrahydrocannabinol. Temporal correlation of the psychologic effects and blood levels after various routes of administration

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12 December 2020

Plasma delta-9-tetrahydrocannabinol in pregnant sheep and fetus after inhalation of smoke from a marijuana cigarette

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12 December 2020

Evidence for the presence of CB1 cannabinoid receptors on peripheral neurones and for the existence of neuronal non-CB1 cannabinoid receptors

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12 December 2020

Gas chromatographic and mass spectrometric studies on the metabolism and pharmacokinetics of Δ1-tetrahydrocannabinol in the rabbit

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12 December 2020

Tolerance Develops to the Disruptive Effects of Δ 9 -Tetrahydrocannabinol on Primate Menstrual Cycle

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12 December 2020

Towards cannabinoid drugs--revisited.

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12 December 2020

Plasma concentrations of delta-9-tetrahydrocannabinol in dams and fetuses following acute or multiple prenatal dosing in rats.

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12 December 2020

Pharmacokinetics and disposition of cannabinoids.

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12 December 2020

Evidence for a new G protein-coupled cannabinoid receptor in mouse brain.

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12 December 2020

Metabolism and distribution of cannabinoids in rats after different methods of administration

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12 December 2020

Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors

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12 December 2020

Cardiovascular actions of cannabinoids and their generation during shock

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12 December 2020

Further urinary metabolites of delta 1-tetrahydrocannabinol in man

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12 December 2020

The passage of 14C-delta-9-tetrahydrocannabinol into the milk of lactating squirrel monkeys

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12 December 2020

Cannabis use and cognitive decline in persons under 65 years of age.

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12 December 2020

Systemic Absorption of Δ9-Tetrahydrocannabinol after Ophthalmic Administration to the Rabbit

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12 December 2020

Pharmacokinetics of delta 9-tetrahydrocannabinol in rabbits following single or multiple intravenous doses

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12 December 2020

Low doses of anandamides inhibit pharmacological effects of delta 9-tetrahydrocannabinol

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12 December 2020

Behavioral pharmacokinetics of marijuana

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12 December 2020

Treatment of Human Spasticity with Δ9-Tetrahydrocannabinol

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12 December 2020

Effect of cannabinoids on spasticity and ataxia in multiple sclerosis

1 reference

12 December 2020

Inhibition of cyclosporine and tetrahydrocannabinol metabolism by cannabidiol in mouse and human microsomes

1 reference

12 December 2020

Laboratory detection of marijuana use. Experience with a photometric immunoassay to measure urinary cannabinoids

1 reference

12 December 2020

Kinetic study of smoking marijuana

1 reference

12 December 2020

Identification in hashish of tetrahydrocannabinol, cannabidiol and cannabinol analogues with a methyl side-chain

1 reference

12 December 2020

Interactions in man of delta-9-tetrahydrocannabinol; II. Cannabinol and cannabidiol

1 reference

12 December 2020

An efficient new cannabinoid antiemetic in pediatric oncology

1 reference

12 December 2020

Single dose kinetics of deuterium labelled Δ1-tetrahydrocannabinol in heavy and light cannabis users

1 reference

12 December 2020

Cannabis, tobacco, and caffeine use modify the blood pressure reactivity protection of ascorbic acid.

1 reference

12 December 2020

Acute and subacute interactions between delta9-tetrahydrocannabinol and other drugs in the rat

1 reference

12 December 2020

Boron trifluoride etherate on silica-A modified Lewis acid reagent (VII). Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells

1 reference

12 December 2020

3H-Δ9-tetrahydrocannabinol, 3H-cannabinol and 3H-cannabidiol: Penetration and regional distribution in rat brain

1 reference

12 December 2020

Acute effects of smoked marijuana and oral delta9-tetrahydrocannabinol on specific airway conductance in asthmatic subjects

1 reference

12 December 2020

Controlled clinical trial of cannabidiol in Huntington's disease

1 reference

12 December 2020

Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol of asthmatic patients

1 reference

12 December 2020

The pharmacological activity of the fatty acid conjugate 11-palmitoyloxy-delta 9-tetrahydrocannabinol

1 reference

12 December 2020

Safety, tolerability, and efficacy of orally administered cannabinoids in MS.

1 reference

12 December 2020

Changes in the cannabinoid receptor binding, G protein coupling, and cyclic AMP cascade in the CNS of rats tolerant to and dependent on the synthetic cannabinoid compound CP55,940

1 reference

12 December 2020

[Active principals of the cannabis and the pharmacology of the cannabinols.]

1 reference

12 December 2020

Do Plasma Concentrations of Δ9-Tetrahydrocannabinol Reflect the Degree of Intoxication?

1 reference

12 December 2020

Cannabidiol and delta 9-tetrahydrocannabinol metabolism. In vitro comparison of mouse and rat liver crude microsome preparations

1 reference

12 December 2020

Intravenous Injection in Man of Δ 9 -Tetrahydrocannabinol and 11-OH-Δ 9 -Tetrahydrocannabinol

1 reference

12 December 2020

Tolerance and disposition of tetrahydrocannabinol in man

1 reference

12 December 2020

Terminal elimination plasma half-life of delta 1-tetrahydrocannabinol (delta 1-THC) in heavy users of marijuana.

1 reference

12 December 2020

Inhibitory effect of the cannabinoid receptor agonist WIN 55,212-2 on pentagastrin-induced gastric acid secretion in the anaesthetized rat.

1 reference

12 December 2020

Urinary excretion half-life of delta 1-tetrahydrocannabinol-7-oic acid in heavy marijuana users after smoking

1 reference

12 December 2020

Forensic aspects of the metabolism and excretion of cannabinoids following oral ingestion of cannabis resin

1 reference

12 December 2020

Treatment of Tourette's syndrome with Delta 9-tetrahydrocannabinol (THC): a randomized crossover trial

1 reference

12 December 2020

Cannabinoid patterns in seedlings of Cannabis sativa L. and their use in the determination of chemical race

1 reference

12 December 2020

Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation.

1 reference

12 December 2020

Marihuana as a therapeutic agent for muscle spasm or spasticity

1 reference

12 December 2020

10.2165/00003088-200342040-00003

Identifiers

DOI

1 reference

Dimensions Publication ID

31 July 2017

1038321199

0 references

1 reference