(Q34123282)

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Mutations within the hMLH1 and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha

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Europe PubMed Central

PubMed publication ID

31 July 2017

Mutations within the hMLH1 and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

DNA mismatch repair

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based on heuristic

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author name string

Markus Räschle

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Patrick Dufner

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Giancarlo Marra

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Josef Jiricny

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

language of work or name

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publication date

10 April 2002

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Europe PubMed Central

PubMed publication ID

31 July 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

31 July 2017

277

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Europe PubMed Central

PubMed publication ID

31 July 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

21810-21820

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Replication errors: cha(lle)nging the genome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

DNA mismatch repair and genetic instability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Mismatch-, MutS-, MutL-, and Helicase II-dependent Unwinding from the Single-strand Break of an Incised Heteroduplex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

MutS and MutL Activate DNA Helicase II in a Mismatch-dependent Manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Molecular mechanisms of DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

DNA mismatch correction in a defined system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Dominant negative mutator mutations in the mutL gene of Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

An atypical topoisomerase II from Archaea with implications for meiotic recombination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

GHKL, an emergent ATPase/kinase superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Topoisomerase II drives DNA transport by hydrolyzing one ATP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Dimerization and N-terminal domain proximity underlie the function of the molecular chaperone heat shock protein 90

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Escherichia coli MutL loads DNA helicase II onto DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Mutation of a mutL homolog in hereditary colon cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

A hPMS2 mutant cell line is defective in strand-specific mismatch repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DMA mismatch repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Mismatch repair defects in cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Drastic genetic instability of tumors and normal tissues in Turcot syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Evidence for a recessive inheritance of Turcot's syndrome caused by compound heterozygous mutations within the PMS2 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Identifying the catalytic residue of the ATPase reaction of DNA gyrase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Functional analysis of hMLH1 variants and HNPCC-related mutations using a human expression system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Analysis of yeast MSH2-MSH6 suggests that the initiation of mismatch repair can be separated into discrete steps

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Structure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Mutations in the B subunit of Escherichia coli DNA gyrase that affect ATP-dependent reactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

ATP-dependent Assembly of a Ternary Complex Consisting of a DNA Mismatch and the Yeast MSH2-MSH6 and MLH1-PMS1 Protein Complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

DNA chain length dependence of formation and dynamics of hMutSalpha.hMutLalpha.heteroduplex complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Hydrolysis of ATP at Only One GyrB Subunit Is Sufficient to Promote Supercoiling by DNA Gyrase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

The Escherichia coli MutL protein physically interacts with MutH and stimulates the MutH-associated endonuclease activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

The importance of ATP binding and hydrolysis by hsp90 in formation and function of protein heterocomplexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

The MutL ATPase is required for mismatch repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Mediating mismatch repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Interaction of Escherichia coli MutS and MutL at a DNA mismatch

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108787200

21 January 2018

Identifiers

10.1074/JBC.M108787200

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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