(Q33966875)

English

The DDE motif in RAG-1 is contributed in trans to a single active site that catalyzes the nicking and transesterification steps of V(D)J recombination

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Europe PubMed Central

PubMed publication ID

30 July 2017

The DDE motif in RAG-1 is contributed in trans to a single active site that catalyzes the nicking and transesterification steps of V(D)J recombination (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Swanson PC

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

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publication date

1 January 2001

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

21

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

449-458

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Trans catalysis in Tn5 transposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Three-dimensional structure of the Tn5 synaptic complex transposition intermediate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Tn5: A molecular window on transposition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Integrating DNA: transposases and retroviral integrases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

A dimer of the lymphoid protein RAG1 recognizes the recombination signal sequence and the complex stably incorporates the high mobility group protein HMG2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

A RAG1 and RAG2 tetramer complex is active in cleavage in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

DNA hairpin opening mediated by the RAG1 and RAG2 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Hairpin coding end opening is mediated by RAG1 and RAG2 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Distinct Roles of RAG1 and RAG2 in Binding the V(D)J Recombination Signal Sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Assembly of a 12/23 Paired Signal Complex: A Critical Control Point in V(D)J Recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

The same two monomers within a MuA tetramer provide the DDE domains for the strand cleavage and strand transfer steps of transposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

RAG-1 and RAG-2-Dependent Assembly of Functional Complexes with V(D)J Recombination Substrates in Solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Stimulation of V(D)J cleavage by high mobility group proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

The Tn7 transposase is a heteromeric complex in which DNA breakage and joining activities are distributed between different gene products.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Initiation of V(D)J recombination in vitro obeying the 12/23 rule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Characterization of broken DNA molecules associated with V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

The V(D)J recombination activating gene, RAG-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

Structural aspects of a higher order nucleoprotein complex: induction of an altered DNA structure at the Mu-host junction of the Mu type 1 transpososome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

28 July 2018

The RAG proteins and V(D)J recombination: complexes, ends, and transposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

Organization and dynamics of the Mu transpososome: recombination by communication between two active sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

Rejoining of DNA by the RAG1 and RAG2 Proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

Similarities between initiation of V(D)J recombination and retroviral integration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

Tn10 and IS10 transposition and chromosome rearrangements: mechanism and regulation in vivo and in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

V(D)J recombination: signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

Initiation of V(D)J recombination in a cell-free system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

Bacterial transposases and retroviral integrases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86595

29 October 2018

The three chemical steps of Tn10/IS10 transposition involve repeated utilization of a single active site

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hairpin formation in Tn5 transposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The RAG1/RAG2 complex constitutes a 3' flap endonuclease: implications for junctional diversity in V(D)J and transpositional recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant circle PCR and recombination PCR for site-specific mutagenesis without PCR product purification

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ragtime jumping

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VDJ recombination: a transposase goes to work

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tn10 transposition via a DNA hairpin intermediate

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

1 reference

https://pubmed.ncbi.nlm.nih.gov/11134333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.21.2.449-458.2001

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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