(Q33799828)

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Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing

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Europe PubMed Central

PubMed publication ID

29 July 2017

Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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inferred from title

reactive oxygen species

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based on heuristic

inferred from title

tumor angiogenesis

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author name string

Hye Jin Jung

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Joong Sup Shim

2

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Europe PubMed Central

PubMed publication ID

29 July 2017

Jiyong Lee

3

1 reference

Europe PubMed Central

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29 July 2017

Young Mi Song

4

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Europe PubMed Central

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29 July 2017

Ki Chung Park

5

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Europe PubMed Central

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29 July 2017

Seung Hoon Choi

6

1 reference

Europe PubMed Central

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29 July 2017

Nam Doo Kim

7

1 reference

Europe PubMed Central

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29 July 2017

Jeong Hyeok Yoon

8

1 reference

Europe PubMed Central

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29 July 2017

Paul T Mungai

9

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Europe PubMed Central

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29 July 2017

Paul T Schumacker

10

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29 July 2017

Ho Jeong Kwon

11

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29 July 2017

language of work or name

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publication date

9 February 2010

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Europe PubMed Central

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29 July 2017

Journal of Biological Chemistry

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Europe PubMed Central

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29 July 2017

285

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Europe PubMed Central

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29 July 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

11584-11595

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

HIF-1alpha: a valid therapeutic target for tumor therapy

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28 July 2018

Membrane potential greatly enhances superoxide generation by the cytochrome bc1 complex reconstituted into phospholipid vesicles

1 reference

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28 July 2018

Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide

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28 July 2018

Rapid identification of a protein binding partner for the marine natural product kahalalide F by using reverse chemical proteomics.

1 reference

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28 July 2018

A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation

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28 July 2018

A semiquinone intermediate generated at the Qo site of the cytochrome bc1 complex: importance for the Q-cycle and superoxide production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Gene expression profiling reveals potential biomarkers of human hepatocellular carcinoma

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Mitochondrial metabolism of reactive oxygen species.

1 reference

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28 July 2018

A new curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Targeting HIF-1 for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Production of reactive oxygen species by mitochondria: central role of complex III.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

A deletion in the human QP-C gene causes a complex III deficiency resulting in hypoglycaemia and lactic acidosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Chemical genomics-based target identification and validation of anti-angiogenic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Large scale domain movement in cytochrome bc(1): a new device for electron transfer in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Structure and function of cytochrome bc complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Up-regulation of vascular endothelial growth factor in response to glucose deprivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Electron transfer by domain movement in cytochrome bc1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Terpestacin, a new syncytium formation inhibitor from Arthrinium sp.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Cloning and sequencing of a cDNA for human mitochondrial ubiquinone-binding protein of complex III

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

The protonmotive Q cycle. Energy transduction by coupling of proton translocation to electron transfer by the cytochrome bc1 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

The role of angiogenesis in tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

28 July 2018

Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.087809

21 January 2018

Chemical genetics resulting from a passion for synthetic organic chemistry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.087809

21 January 2018

Enantioselective synthesis of (-)-terpestacin and (-)-fusaproliferin: clarification of optical rotational measurements and absolute configurational assignments establishes a homochiral structural series

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.087809

21 January 2018

Development of anangiogenesis-focused cDNA chip and validation of its functionality.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.087809

21 January 2018

Silibinin inhibits hypoxia-inducible factor-1alpha and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.087809

21 January 2018

Baicalein suppresses hypoxia-induced HIF-1alpha protein accumulation and activation through inhibition of reactive oxygen species and PI 3-kinase/Akt pathway in BV2 murine microglial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.087809

21 January 2018

The mechanism of mitochondrial superoxide production by the cytochrome bc1 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.087809

21 January 2018

Isolation and characterisation of the linked genes APA2 and QCR7, coding for Ap4A phosphorylase II and the 14 kDa subunit VII of the mitochondrial bc1-complex in the yeast Kluyveromyces lactis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.087809

21 January 2018

The C-terminus of the 14-kDa subunit of ubiquinol-cytochrome-c oxidoreductase of the yeast Saccharomyces cerevisiae is involved in the assembly of a functional enzyme.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.087809

21 January 2018

Mutational analysis of BRAF and K-ras in gastric cancers: absence of BRAF mutations in gastric cancers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.087809

21 January 2018

Purification and biochemical properties of glutathione S-transferase from Lactuca sativa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

30 October 2018

Mutations in respiratory chain complexes and human diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

30 October 2018

Osteoblast expression of vascular endothelial growth factor is modulated by the extracellular microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857036

30 October 2018

Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enantioselective synthesis of (-)-terpestacin and structural revision of siccanol using catalytic stereoselective fragment couplings and macrocyclizations

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-angiogenic activity of terpestacin, a bicyclo sesterterpene from Embellisia chlamydospora

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug target validation and identification of secondary drug target effects using DNA microarrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.087809

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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