(Q33788829)

29 July 2017

0 references

IL-15: a central regulator of celiac disease immunopathology (English)

1 reference

29 July 2017

Valérie Abadie

1

1 reference

29 July 2017

Bana Jabri

series ordinal

2

1 reference

29 July 2017

publication date

1 July 2014

1 reference

29 July 2017

published in

Immunological Reviews

1 reference

29 July 2017

volume

260

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29 July 2017

issue

1

1 reference

29 July 2017

page(s)

221-234

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Characterization of the IL-15 niche in primary and secondary lymphoid organs in vivo

29 July 2017

cites work

1 reference

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The biology of IL-15: implications for cancer therapy and the treatment of autoimmune disorders

28 July 2018

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Interleukin 15 primes natural killer cells to kill via NKG2D and cPLA2 and this pathway is active in psoriatic arthritis

28 July 2018

1 reference

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Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes

28 July 2018

1 reference

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Transcriptional regulation of IL-15 expression during hematopoiesis

28 July 2018

1 reference

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Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL-15Rα

28 July 2018

1 reference

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IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner

28 July 2018

1 reference

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Triggers and drivers of autoimmunity: lessons from coeliac disease

28 July 2018

1 reference

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Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-γ-producing cells

28 July 2018

1 reference

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Tofacitinib, a janus kinase inhibitor demonstrates efficacy in an IL-15 transgenic mouse model that recapitulates pathologic manifestations of celiac disease

28 July 2018

1 reference

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Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15

28 July 2018

1 reference

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Paracrine and transpresentation functions of IL-15 are mediated by diverse splice versions of IL-15Rα in human monocytes and dendritic cells

28 July 2018

1 reference

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Regulating the immune system via IL-15 transpresentation

28 July 2018

1 reference

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Identification of a potential physiological precursor of aberrant cells in refractory coeliac disease type II.

28 July 2018

1 reference

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Cutting edge: the role of IFN-α receptor and MyD88 signaling in induction of IL-15 expression in vivo

28 July 2018

1 reference

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Activation and inhibition of transglutaminase 2 in mice

28 July 2018

1 reference

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Cytokine network in psoriasis revisited

28 July 2018

1 reference

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European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease.

28 July 2018

1 reference

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IL-15 regulates homeostasis and terminal maturation of NKT cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use

28 July 2018

1 reference

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Potential celiac patients: a model of celiac disease pathogenesis.

28 July 2018

1 reference

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Enteropathy-associated T-cell lymphoma: clinical and histological findings from the international peripheral T-cell lymphoma project.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Integration of genetic and immunological insights into a model of celiac disease pathogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Role of IL-15 in immune-mediated and infectious diseases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Thymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

HLA-DQ2-restricted gluten-reactive T cells produce IL-21 but not IL-17 or IL-22.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Mucosal recovery and mortality in adults with celiac disease after treatment with a gluten-free diet

28 July 2018

1 reference

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Tissue-mediated control of immunopathology in coeliac disease

28 July 2018

1 reference

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Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes

28 July 2018

1 reference

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Secretion and biological activity of short signal peptide IL-15 is chaperoned by IL-15 receptor alpha in vivo

28 July 2018

1 reference

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High levels of proinflammatory cytokines, but not markers of tissue injury, in unaffected intestinal areas from patients with IBD

28 July 2018

1 reference

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New insights into the regulation of T cells by gamma(c) family cytokines

28 July 2018

1 reference

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Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15.

28 July 2018

1 reference

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Expression of IL-15RA or an IL-15/IL-15RA fusion on CD8+ T cells modifies adoptively transferred T-cell function in cis

28 July 2018

1 reference

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Dendritic cells drive memory CD8 T-cell homeostasis via IL-15 transpresentation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

IL-23/IL-17 immunity as a hallmark of Crohn's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

IL-15Ralpha chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Membrane bound IL-15 is increased on CD14 monocytes in early stages of MS.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Intracellular interaction of interleukin-15 with its receptor alpha during production leads to mutual stabilization and increased bioactivity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Survival in refractory coeliac disease and enteropathy-associated T-cell lymphoma: retrospective evaluation of single-centre experience

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Emerging cytokine targets in rheumatoid arthritis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Dendritic cells prime natural killer cells by trans-presenting interleukin 15

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Ito cells are liver-resident antigen-presenting cells for activating T cell responses

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Mechanisms of disease: immunopathogenesis of celiac disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

28 July 2018

1 reference

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IL-15/IL-15 receptor biology: a guided tour through an expanding universe

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Novel IL-15 isoforms generated by alternative splicing are expressed in the intestinal epithelium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Reprogramming of CTLs into natural killer-like cells in celiac disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Preclinical and phase I clinical trial of blockade of IL-15 using Mikbeta1 monoclonal antibody in T cell large granular lymphocyte leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Interleukin 15 controls the generation of the restricted T cell receptor repertoire of gamma delta intestinal intraepithelial lymphocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease.

28 July 2018

1 reference

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Immunomodulatory dendritic cells in intestinal lamina propria.

28 July 2018

1 reference

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Refractory coeliac disease

28 July 2018

1 reference

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Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Targeting the interleukin-15/interleukin-15 receptor system in inflammatory autoimmune diseases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Distinct cell types control lymphoid subset development by means of IL-15 and IL-15 receptor alpha expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Transregulation of memory CD8 T-cell proliferation by IL-15Rα+ bone marrow–derived cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

TCR specificity dictates CD94/NKG2A expression by human CTL.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Structural basis for gluten intolerance in celiac sprue

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

A role for IL-15 in driving the onset of spontaneous autoimmune thyroiditis?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Reduced expression of Bcl-2 in CD8+ T cells deficient in the IL-15 receptor alpha-chain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Interleukin-15 prevents mouse mast cell apoptosis through STAT6-mediated Bcl-xL expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

IL-15 drives the specific migration of CD94+ and TCR-gammadelta+ intraepithelial lymphocytes in organ cultures of treated celiac patients.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Role of interferon alpha in promoting T helper cell type 1 responses in the small intestine in coeliac disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Interleukin 15: biology and relevance to human disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma. French Coeliac Disease Study Group.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Interleukin-15 and its impact on neutrophil function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

T cells orchestrate intestinal mucosal shape and integrity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Autoantibodies to tissue transglutaminase as predictors of celiac disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

The 5' untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Translational efficiency is up-regulated by alternative exon in murine IL-15 mRNA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse-human rheumatoid arthritis model In vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Abnormal intestinal intraepithelial lymphocytes in refractory sprue

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

A potential role for interleukin-15 in the regulation of human natural killer cell survival

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Detection of IL-12, IL-13, and IL-15 messenger ribonucleic acid in the thyroid of patients with autoimmune thyroid disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Intestinal epithelial cells both express and respond to interleukin 15

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Interleukin (IL) 15/IL-T production by the adult T-cell leukemia cell line HuT-102 is associated with a human T-cell lymphotrophic virus type I region /IL-15 fusion message that lacks many upstream AUGs that normally attenuates IL-15 mRNA translatio

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Interleukin-2-induced tyrosine phosphorylation of Shc proteins correlates with factor-dependent T cell proliferation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Expression of relB is required for the development of thymic medulla and dendritic cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Cellular infiltrate of jejunal biopsies in adult coeliac disease (ACD) in relation to gluten withdrawal

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

28 July 2018

1 reference

Selective expansion of intraepithelial lymphocytes expressing the HLA-E–specific natural killer receptor CD94 in celiac disease

21 January 2018

1 reference

NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment

21 January 2018

1 reference

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

21 January 2018

1 reference

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

21 January 2018

1 reference

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

21 January 2018

1 reference

Distinct pathways involving the FK506-binding proteins 12 and 12.6 underlie IL-2-versus IL-15-mediated proliferation of T cells

21 January 2018

1 reference

Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain

21 January 2018

1 reference

IL-15/IL-15Ralpha-mediated avidity maturation of memory CD8+ T cells.

21 January 2018

1 reference

No Requirement of Trans Presentations of IL-15 for Human CD8 T Cell Proliferation

21 January 2018

1 reference

Circulating IL-15 exists as heterodimeric complex with soluble IL-15Rα in human and mouse serum

21 January 2018

1 reference

Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain

21 January 2018

1 reference

IL-15Rα of Radiation-Resistant Cells Is Necessary and Sufficient for Thymic Invariant NKT Cell Survival and Functional Maturation

21 January 2018

1 reference

Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development

21 January 2018

1 reference

Dendritic cells support the in vivo development and maintenance of NK cells via IL-15 trans-presentation.

21 January 2018

1 reference

Hepatic interleuklin 15 (IL-15) expression: implications for local NK/NKT cell homeostasis and development

21 January 2018

1 reference

Macrophage- and dendritic-cell-derived interleukin-15 receptor alpha supports homeostasis of distinct CD8+ T cell subsets

21 January 2018

1 reference

MyD88-dependent signaling for IL-15 production plays an important role in maintenance of CD8 alpha alpha TCR alpha beta and TCR gamma delta intestinal intraepithelial lymphocytes.

21 January 2018

1 reference

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

21 January 2018

1 reference

Control of homeostasis of CD8+ memory T cells by opposing cytokines.

21 January 2018

1 reference

Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells

21 January 2018

1 reference

Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

21 January 2018

1 reference

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

21 January 2018

1 reference

Cutting edge: murine dendritic cells require IL-15R alpha to prime NK cells

21 January 2018

1 reference

Interleukin-15 improves cytotoxicity of natural killer cells via up-regulating NKG2D and cytotoxic effector molecule expression as well as STAT1 and ERK1/2 phosphorylation

21 January 2018

1 reference

Intraepithelial lymphocytes in celiac disease immunopathology

21 January 2018

1 reference

IL-15 Does Not Affect IEL Development in the Thymus but Regulates Homeostasis of Putative Precursors and Mature CD8 + IELs in the Intestine

21 January 2018

1 reference

Trans-presentation of IL-15 by intestinal epithelial cells drives development of CD8alphaalpha IELs.

21 January 2018

1 reference

IL-15 modulates the balance between Bcl-2 and Bim via a Jak3/1-PI3K-Akt-ERK pathway to promote CD8αα+ intestinal intraepithelial lymphocyte survival

21 January 2018

1 reference

Enforced expression of Bcl-2 partially restores cell numbers but not functions of TCRgammadelta intestinal intraepithelial T lymphocytes in IL-15-deficient mice.

21 January 2018

1 reference

Interleukin 15 is a potent stimulant of intraepithelial lymphocytes

21 January 2018

1 reference

Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease

21 January 2018

1 reference

Interleukin-15 expression affects homeostasis and function of B cells through NK cell-derived interferon-gamma.

21 January 2018

1 reference

Follicular dendritic cells produce IL-15 that enhances germinal center B cell proliferation in membrane-bound form

21 January 2018

1 reference

Survival adjustment of mature dendritic cells by IL-15.

21 January 2018

1 reference

The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis

21 January 2018

1 reference

Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis

21 January 2018

1 reference

IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate

21 January 2018

1 reference

Production of interleukin-7 and interleukin-15 by fibroblast-like synoviocytes from patients with rheumatoid arthritis

21 January 2018

1 reference

The role of IL-15 in central nervous system disorders

21 January 2018

1 reference

Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model

21 January 2018

1 reference

IL-15 is elevated in serum patients with type 1 diabetes mellitus

21 January 2018

1 reference

Possible involvement of the interleukin-15 and interleukin-15 receptor system in a heightened state of lamina propria B cell activation and differentiation in patients with inflammatory bowel disease.

21 January 2018

1 reference

21 January 2018

1 reference

Interleukin 15 mediates epithelial changes in celiac disease

21 January 2018

1 reference

Specificity of tissue transglutaminase explains cereal toxicity in celiac disease

21 January 2018

1 reference

Extracellular transglutaminase 2 is catalytically inactive, but is transiently activated upon tissue injury

21 January 2018

1 reference

Peripheral deletion of antigen-reactive T cells in oral tolerance.

21 January 2018

1 reference

Mesenteric lymph nodes at the center of immune anatomy

21 January 2018

1 reference

Interleukin 15 and CD4⁺ T cells cooperate to promote small intestinal enteropathy in response to dietary antigen.

21 January 2018

1 reference

CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis.

21 January 2018

1 reference

Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis

21 January 2018

1 reference

CD4+ CD25+ T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis

21 January 2018

1 reference

Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease.

21 January 2018

1 reference

Expression and functional characterization of FOXP3+ CD4+ regulatory T cells in ulcerative colitis

21 January 2018

1 reference

Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia

21 January 2018

1 reference

Inhibition of TGF-β Signaling by IL-15: A New Role for IL-15 in the Loss of Immune Homeostasis in Celiac Disease

21 January 2018

1 reference

IL-15 renders conventional lymphocytes resistant to suppressive functions of regulatory T cells through activation of the phosphatidylinositol 3-kinase pathway

21 January 2018

1 reference

IL-15 Interferes With Suppressive Activity of Intestinal Regulatory T Cells Expanded in Celiac Disease

21 January 2018

1 reference

A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease.

21 January 2018

1 reference

Interleukin 21 up-regulates perforin-mediated cytotoxic activity of human intra-epithelial lymphocytes.

21 January 2018

1 reference

IL-15 positively regulates IL-21 production in celiac disease mucosa.

21 January 2018

1 reference

Plasmacytoid dendritic cells are scarcely represented in the human gut mucosa and are not recruited to the celiac lesion

21 January 2018

1 reference

Onset of coeliac disease during treatment with interferon for chronic hepatitis C.

21 January 2018

1 reference

Effects of IFN-α as a signal-3 cytokine on human naïve and antigen-experienced CD8(+) T cells

21 January 2018

1 reference

IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation

21 January 2018

1 reference

CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

CD4+CD25bright T cells in human intestinal lamina propria as regulatory cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

Death deflected: IL-15 inhibits TNF-alpha-mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL-15Ralpha chain

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066219

IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation

30 October 2018

1 reference

12 December 2020

Serum antibodies to gliadin in coeliac disease after gluten withdrawal

1 reference

12 December 2020

Interleukin‐15 preferentially promotes the growth of intestinal intraepithelial lymphocytes bearing γδ T cell receptor in mice

1 reference

12 December 2020

Differential intracellular trafficking, secretion and endosomal localization of two IL-15 isoforms

1 reference

12 December 2020

IL-15 converts human intestinal intraepithelial lymphocytes to CD94 producers of IFN-gamma and IL-10, the latter promoting Fas ligand-mediated cytotoxicity

1 reference

12 December 2020

Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells

1 reference

12 December 2020

Increased numbers of interleukin-15-expressing cells in active ulcerative colitis

1 reference

12 December 2020

Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms

1 reference

12 December 2020

Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls

1 reference

12 December 2020

Interleukin-15 inhibits spontaneous apoptosis in human eosinophils via autocrine production of granulocyte macrophage-colony stimulating factor and nuclear factor-kappaB activation

1 reference

12 December 2020

Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease

1 reference

12 December 2020

Tissue transglutaminase autoantibody enzyme-linked immunosorbent assay in detecting celiac disease

1 reference

12 December 2020

IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

1 reference

12 December 2020

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

1 reference

12 December 2020

Proinflammatory interferon-gamma--inducing monokines (interleukin-12, interleukin-18, interleukin-15)--serum profile in patients with systemic lupus erythematosus

1 reference

12 December 2020

Homeostasis of V alpha 14i NKT cells

1 reference

12 December 2020

IL-15 is elevated in sera of patients with relapsing-remitting multiple sclerosis

1 reference

12 December 2020

IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4+ T Lymphocytes

1 reference

12 December 2020

Coeliac disease: a histological follow-up study

1 reference

12 December 2020

Rotavirus and celiac disease: clues to the pathogenesis and perspectives on prevention

1 reference

12 December 2020

CD4+NKG2D+ T Cells in Crohn’s Disease Mediate Inflammatory and Cytotoxic Responses Through MICA Interactions

1 reference

12 December 2020

Evidence for the role of interferon-alfa production by dendritic cells in the Th1 response in celiac disease

1 reference

12 December 2020

Increasing prevalence of coeliac disease over time

1 reference

12 December 2020

Characterization of FOXP3+CD4+ regulatory T cells in Crohn's disease

1 reference

12 December 2020

Inhibitory effect of dietary n-3 polyunsaturated fatty acids to intestinal IL-15 expression is associated with reduction of TCRalphabeta+CD8alpha+CD8beta-intestinal intraepithelial lymphocytes

1 reference

12 December 2020

Interleukin 21 contributes to the mucosal T helper cell type 1 response in coeliac disease

1 reference

12 December 2020

Elevated expression of transmembrane IL-15 in immune cells correlates with the development of murine lupus: a potential target for immunotherapy against SLE

1 reference

12 December 2020

Interleukin-15 and its soluble receptor mediate the response to infliximab in patients with Crohn's disease

1 reference

12 December 2020

Immunoregulatory pathways are active in the small intestinal mucosa of patients with potential celiac disease

1 reference

12 December 2020

IL-15 is highly expressed in inflammatory bowel disease and regulates local T cell-dependent cytokine production

1 reference

12 December 2020

Colonic expression and synthesis of interleukin 13 and interleukin 15 in inflammatory bowel disease

1 reference

12 December 2020

Serum interleukin-15 is elevated in systemic lupus erythematosus

1 reference

12 December 2020

Functional CD4+CD25high regulatory T cells are enriched in the colonic mucosa of patients with active ulcerative colitis and increase with disease activity

1 reference

12 December 2020

Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis

1 reference

12 December 2020

IgA antigliadin antibodies: a marker of mucosal damage in childhood coeliac disease

1 reference

12 December 2020

Identifiers

DOI

10.1111/IMR.12191

1 reference

29 July 2017

1 reference

29 July 2017

1 reference