(Q33760802)

29 July 2017

title

HapX positively and negatively regulates the transcriptional response to iron deprivation in Cryptococcus neoformans (English)

1 reference

29 July 2017

HapX Positively and Negatively Regulates the Transcriptional Response to Iron Deprivation in Cryptococcus neoformans (English)

1 reference

10.1371/JOURNAL.PPAT.1001209

DOI

https://api.crossref.org/works/10.1371/JOURNAL.PPAT.1001209

uroporphyrinogen decarboxylase, putative

19 November 2024

main subject

0 references

porphobilinogen deaminase

0 references

Transcriptional activator HAP2, putative

0 references

CCAAT-binding transcription factor HapX

0 references

fungal Zn(2)-Cys(6) binuclear cluster domain-containing protein, putative

0 references

coproporphyrinogen-III oxidase

0 references

transcriptional activator, putative

0 references

transcriptional activator hap5

0 references

uroporphyrinogen-III synthase, putative

0 references

uroporphyrinogen decarboxylase

0 references

hypothetical protein

0 references

Putative Zn(II)2Cys6 transcription factor

0 references

Putative Zn(II)2Cys6 transcription factor

0 references

CCAAT-binding transcription factor HapX

0 references

Transcriptional activator HAP2, putative

0 references

coproporphyrinogen III oxidase

0 references

transcriptional activator

0 references

transcriptional activator, variant

0 references

transcriptional activator hap5

0 references

porphobilinogen deaminase

0 references

uroporphyrinogen-III synthase

0 references

Cryptococcus neoformans

1 reference

3

Guanggan Hu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21124817

19 November 2024

4

Joyce Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21124817

19 November 2024

8

James W. Kronstad

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21124817

19 November 2024

author name string

Won Hee Jung

1

1 reference

29 July 2017

Sanjay Saikia

2

1 reference

29 July 2017

Carlen Ka-Yin Fung

5

1 reference

29 July 2017

Cletus D'Souza

6

1 reference

29 July 2017

Rick White

7

1 reference

29 July 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21124817

19 November 2024

publication date

24 November 2010

1 reference

full work available at URL

29 July 2017

https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1001209&type=printable

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21124817

https://europepmc.org/articles/PMC2991262

19 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21124817

https://europepmc.org/articles/PMC2991262?pdf=render

19 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21124817

http://dx.plos.org/10.1371/journal.ppat.1001209

19 November 2024

1 reference

10.1371/JOURNAL.PPAT.1001209

DOI

https://api.crossref.org/works/10.1371/JOURNAL.PPAT.1001209

19 November 2024

1 reference

29 July 2017

volume

6

1 reference

29 July 2017

issue

11

1 reference

29 July 2017

page(s)

e1001209

1 reference

Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

24 November 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States

21 June 2018

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Interaction of Cryptococcus neoformans Rim101 and protein kinase A regulates capsule.

21 June 2018

1 reference

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21 June 2018

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The CCAAT-binding complex coordinates the oxidative stress response in eukaryotes

21 June 2018

1 reference

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Regulatory diversity of TUP1 in Cryptococcus neoformans

21 June 2018

1 reference

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Iron acquisition and transcriptional regulation

21 June 2018

1 reference

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Role of ferroxidases in iron uptake and virulence of Cryptococcus neoformans.

21 June 2018

1 reference

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Both Php4 function and subcellular localization are regulated by iron via a multistep mechanism involving the glutaredoxin Grx4 and the exportin Crm1.

21 June 2018

1 reference

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Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

21 June 2018

1 reference

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Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans

21 June 2018

1 reference

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SreA-mediated iron regulation in Aspergillus fumigatus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Iron availability and infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Candida albicans ferric reductases are differentially regulated in response to distinct forms of iron limitation by the Rim101 and CBF transcription factors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Iron source preference and regulation of iron uptake in Cryptococcus neoformans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Key function for the CCAAT-binding factor Php4 to regulate gene expression in response to iron deficiency in fission yeast.

21 June 2018

1 reference

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Yap5 is an iron-responsive transcriptional activator that regulates vacuolar iron storage in yeast

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Iron and fungal pathogenesis: a case study with Cryptococcus neoformans.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Interaction of HapX with the CCAAT-binding complex--a novel mechanism of gene regulation by iron

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

A link between virulence and homeostatic responses to hypoxia during infection by the human fungal pathogen Cryptococcus neoformans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Heme acquisition by hemophores

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Iron regulation of the major virulence factors in the AIDS-associated pathogen Cryptococcus neoformans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

A transcription factor cascade involving Fep1 and the CCAAT-binding factor Php4 regulates gene expression in response to iron deficiency in the fission yeast Schizosaccharomyces pombe

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Staphylococcus aureus redirects central metabolism to increase iron availability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

The Aspergillus fumigatus siderophore biosynthetic gene sidA, encoding L-ornithine N5-oxygenase, is required for virulence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Coordinated remodeling of cellular metabolism during iron deficiency through targeted mRNA degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Iron and microbial infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Cryptococcus neoformans capsule biosynthesis and regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Regulatory networks affected by iron availability in Candida albicans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Using the gene ontology for microarray data mining: a comparison of methods and application to age effects in human prefrontal cortex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Induction of Capsule Growth inCryptococcus neoformansby Mammalian Serum and CO2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

A yeast under cover: the capsule of Cryptococcus neoformans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Molecular mechanisms of iron uptake in fungi

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

A PCR-based strategy to generate integrative targeting alleles with large regions of homology.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Variance stabilization applied to microarray data calibration and to the quantification of differential expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

T-Coffee: A novel method for fast and accurate multiple sequence alignment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Ferrous iron uptake in Cryptococcus neoformans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

A yeast sterol auxotroph ( erg 25) is rescued by addition of azole antifungals and reduced levels of heme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

Biochemical studies of phenoloxidase and utilization of catecholamines in Cryptococcus neoformans.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

The HAP2 subunit of yeast CCAAT transcriptional activator contains adjacent domains for subunit association and DNA recognition: model for the HAP2/3/4 complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991262

The emergence of Cryptococcus gattii in British Columbia and the Pacific Northwest.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001209

Regulation of cryptococcal capsular polysaccharide by iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001209

Iron-regulated transcription and capsule formation in the fungal pathogen Cryptococcus neoformans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001209

Novel regulatory function for the CCAAT-binding factor in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001209

Metabolites released by Cryptococcus neoformans var. neoformans and var. gattii differentially affect human neutrophil function

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001209

The iron- and cAMP-regulated gene SIT1 influences ferrioxamine B utilization, melanization and cell wall structure in Cryptococcus neoformans

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21124817

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Discordant regulation of phenoloxidase and capsular polysaccharide in Cryptococcus neoformans

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21124817

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Double-joint PCR: a PCR-based molecular tool for gene manipulations in filamentous fungi

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21124817

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PPAT.1001209

1 reference

29 July 2017

1 reference

29 July 2017

1 reference