(Q33748196)

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Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

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Arnau Vina-Vilaseca

1

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Europe PubMed Central

PubMed publication ID

29 July 2017

Alexander Sorkin

2

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Europe PubMed Central

PubMed publication ID

29 July 2017

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publication date

5 January 2010

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Europe PubMed Central

PubMed publication ID

29 July 2017

number of pages

12

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

29 July 2017

285

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Europe PubMed Central

PubMed publication ID

29 July 2017

10

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Europe PubMed Central

PubMed publication ID

29 July 2017

7645-7656

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Europe PubMed Central

PubMed publication ID

29 July 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2844211/fullTextXML

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The HECT domain of the ubiquitin ligase Rsp5 contributes to substrate recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Physiological functions of the HECT family of ubiquitin ligases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Glucose-induced ubiquitylation and endocytosis of the yeast Jen1 transporter: role of lysine 63-linked ubiquitin chains

1 reference

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21 June 2018

Nedd4-2-mediated ubiquitination facilitates processing of surfactant protein-C

1 reference

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21 June 2018

K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Polyubiquitination by HECT E3s and the determinants of chain type specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Regulation of the RSP5 ubiquitin ligase by an intrinsic ubiquitin-binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interaction

1 reference

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21 June 2018

The role of Rsp5 ubiquitin ligase in regulation of diverse processes in yeast cells.

1 reference

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21 June 2018

Functional regulation of the epithelial Na+ channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Versatile role of the yeast ubiquitin ligase Rsp5p in intracellular trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Nedd4-2 induces endocytosis and degradation of proteolytically cleaved epithelial Na+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Regulation of receptors and transporters by ubiquitination: new insights into surprisingly similar mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Nedd4-2 catalyzes ubiquitination and degradation of cell surface ENaC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Proteasome-independent functions of ubiquitin in endocytosis and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Three ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Monoubiquitylation: a recurrent theme in membrane protein transport.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Role of ubiquitylation in cellular membrane transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Minireview: regulation of epithelial Na+ channel trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

E3 ubiquitin ligases as regulators of membrane protein trafficking and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Nedd4-2 isoforms differentially associate with ENaC and regulate its activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Role of Nedd4-2 and polyubiquitination in epithelial sodium channel degradation in untransfected renal A6 cells expressing endogenous ENaC subunits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Constitutive and protein kinase C-induced internalization of the dopamine transporter is mediated by a clathrin-dependent mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Polyubiquitin chains: polymeric protein signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Participation of the ubiquitin-conjugating enzyme UBE2E3 in Nedd4-2-dependent regulation of the epithelial Na+ channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Alternate promoters and variable splicing lead to hNedd4-2 isoforms with a C2 domain and varying number of WW domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Characterization of the interactions between Nedd4-2, ENaC, and sgk-1 using surface plasmon resonance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

The role of Nedd4/Nedd4-like dependant ubiquitylation in epithelial transport processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

The role of individual Nedd4-2 (KIAA0439) WW domains in binding and regulating epithelial sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Ubiquitin is required for sorting to the vacuole of the yeast general amino acid permease, Gap1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Ubiquitin Lys63 is involved in ubiquitination of a yeast plasma membrane protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844211

21 June 2018

Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.058990

21 January 2018

Substrate- and ubiquitin-dependent trafficking of the yeast siderophore transporter Sit1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.058990

21 January 2018

Enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.058990

21 January 2018

AMPK controls epithelial Na(+) channels through Nedd4-2 and causes an epithelial phenotype when mutated

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.058990

21 January 2018

Arrestin-like proteins mediate ubiquitination and endocytosis of the yeast metal transporter Smf1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.058990

21 January 2018

Affinity and specificity of interactions between Nedd4 isoforms and the epithelial Na+ channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.058990

21 January 2018

Post-translational regulation of EAAT2 function by co-expressed ubiquitin ligase Nedd4-2 is impacted by SGK kinases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.058990

21 January 2018

Molecular mechanisms of coupled monoubiquitination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.058990

21 January 2018

RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20051513

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ubiquitin-protein ligases Nedd4 and Nedd4-2 show similar ubiquitin-conjugating enzyme specificities

1 reference

https://pubmed.ncbi.nlm.nih.gov/20051513

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell Survival through Trk Neurotrophin Receptors Is Differentially Regulated by Ubiquitination

1 reference

https://pubmed.ncbi.nlm.nih.gov/20051513

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.058990

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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