(Q33717685)

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Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 July 2017

Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

author name string

Brandon M Stell

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Stephen G Brickley

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

C Y Tang

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Mark Farrant

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Istvan Mody

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

language of work or name

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publication date

17 November 2003

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

100

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

14439-14444

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

A neurosteroid anesthetic, alphaxalone, inhibits nicotinic acetylcholine receptors in cultured bovine adrenal chromaffin cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Gain modulation from background synaptic input

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Pharmacological characterization of a novel cell line expressing human alpha(4)beta(3)delta GABA(A) receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

The human gamma-aminobutyric acid A receptor delta (GABRD) gene: molecular characterisation and tissue-specific expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Receptors with different affinities mediate phasic and tonic GABA(A) conductances in hippocampal neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Selective modulation of tonic and phasic inhibitions in dentate gyrus granule cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Enhanced neurosteroid potentiation of ternary GABA(A) receptors containing the delta subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

In vivo monitoring of amino acids by direct sampling of brain extracellular fluid at ultralow flow rates and capillary electrophoresis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Pre-menstrual steroids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Paradoxical reduction of synaptic inhibition by vigabatrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

alpha4beta3delta GABA(A) receptors characterized by fluorescence resonance energy transfer-derived measurements of membrane potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Structural determinants of fast desensitization and desensitization-deactivation coupling in GABAa receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Targeted disruption of the GABA(A) receptor delta subunit gene leads to an up-regulation of gamma 2 subunit-containing receptors in cerebellar granule cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

GABAA Receptors Containing the α4‐Subunit: Prevalence, Distribution, Pharmacology, and Subunit Architecture In Situ

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Development of action potential-dependent and independent spontaneous GABAA receptor-mediated currents in granule cells of postnatal rat cerebellum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Ligand-gated ion channel subunit partnerships: GABAA receptor alpha6 subunit gene inactivation inhibits delta subunit expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Long-term depression in hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Which GABAA-receptor subtypes really occur in the brain?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Nonvesicular release of neurotransmitter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Neuroactive steroid modulation of GABAA receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

In vivo determination of extracellular concentration of amino acids in the rat hippocampus. A method based on brain dialysis and computerized analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Regional distribution and extracellular levels of amino acids in rat central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Cerebellar GABAA receptor selective for a behavioural alcohol antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Neurosteroids act on recombinant human GABAA receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Cloning, pharmacological characteristics and expression pattern of the rat GABAA receptor alpha 4 subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Neurosteroids: endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

Neuroactive steroids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

21 June 2018

GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Tonic and spillover inhibition of granule cells control information flow through cerebellar cortex

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Multiple modes of GABAergic inhibition of rat cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

GABA(A) receptor changes in delta subunit-deficient mice: altered expression of alpha4 and gamma2 subunits in the forebrain

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Neurosteroids: 3 alpha-hydroxy-5 alpha-pregnan-20-one and its precursors in the brain, plasma, and steroidogenic glands of male and female rats

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Prevention of the stress-induced increase in the concentration of neuroactive steroids in rat brain by long-term administration of mirtazapine but not of fluoxetine

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Nicotine-induced changes in cerebrocortical neuroactive steroids and plasma corticosterone concentrations in the rat.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Effects of a naturally occurring neurosteroid on GABAA IPSCs during development in rat hippocampal or cerebellar slices

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

GABA(A) receptor delta subunit deletion prevents neurosteroid modulation of inhibitory synaptic currents in cerebellar neurons.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Neuroactive steroids induce GABA(A) receptor-mediated depolarizing postsynaptic potentials in hippocampal CA1 pyramidal cells of the rat.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Vigabatrin induces tonic inhibition via GABA transporter reversal without increasing vesicular GABA release.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Alpha1 and alpha6 subunits specify distinct desensitization, deactivation and neurosteroid modulation of GABA(A) receptors containing the delta subunit

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Altered receptor subtypes in the forebrain of GABA(A) receptor delta subunit-deficient mice: recruitment of gamma 2 subunits.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Decreased GABAA-receptor clustering results in enhanced anxiety and a bias for threat cues

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Intact sorting, targeting, and clustering of gamma-aminobutyric acid A receptor subtypes in hippocampal neurons in vitro

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

Shunting inhibition modulates neuronal gain during synaptic excitation.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

The interaction between neuroactive steroids and the σ1 receptor function: behavioral consequences and therapeutic opportunities

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2435457100

21 January 2018

GABA uptake regulates cortical excitability via cell type-specific tonic inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

30 October 2018

Neurosteroid modulation of GABA IPSCs is phosphorylation dependent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

30 October 2018

Delta subunit inhibits neurosteroid modulation of GABAA receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

30 October 2018

Properties of putative cerebellar gamma-aminobutyric acid A receptor isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

30 October 2018

Neurosteroids modulate calcium currents in hippocampal CA1 neurons via a pertussis toxin-sensitive G-protein-coupled mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283610

30 October 2018

Modulation of native and recombinant GABAA receptors by endogenous and synthetic neuroactive steroids

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic integration in a model of cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.2435457100

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

2003PNAS..10014439S

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

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