(Q33716122)

28 July 2017

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title

Protein tyrosine kinase inhibitors as novel therapeutic agents (English)

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28 July 2017

Levitzki A

1

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28 July 2017

publication date

1 May 1999

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Pharmacology & Therapeutics

28 July 2017

published in

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28 July 2017

volume

82

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28 July 2017

issue

2-3

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28 July 2017

page(s)

231-239

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PDGF-receptor tyrosine kinase blocker AG1295 selectively attenuates smooth muscle cell growth in vitro and reduces neointimal formation after balloon angioplasty in swine

28 July 2017

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Suppression of experimental autoimmune encephalomyelitis by tyrphostin AG-556

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Tyrosine kinase inhibitors. 8. An unusually steep structure-activity relationship for analogues of 4-(3-bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a potent inhibitor of the epidermal growth factor receptor

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7 January 2021

RETRACTED: Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class

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The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

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The inhibition of EGF-dependent proliferation of keratinocytes by tyrphostin tyrosine kinase blockers

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A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

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Tyrphostins. 5. Potent inhibitors of platelet-derived growth factor receptor tyrosine kinase: structure-activity relationships in quinoxalines, quinolines, and indole tyrphostins

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Tyrphostins IV--highly potent inhibitors of EGF receptor kinase. Structure-activity relationship study of 4-anilidoquinazolines

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Controlled delivery of a tyrphostin inhibits intimal hyperplasia in a rat carotid artery injury model

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7 January 2021

Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

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7 January 2021

Crystal structure of the tyrosine kinase domain of the human insulin receptor

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7 January 2021

Inhibition of cellular ras prevents smooth muscle cell proliferation after vascular injury in vivo

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7 January 2021

Protein tyrosine phosphorylation mediates TNF-induced endothelial-neutrophil adhesion in vitro

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7 January 2021

Phosphorylation site-specific inhibition of platelet-derived growth factor beta-receptor autophosphorylation by the receptor blocking tyrphostin AG1296.

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Signal-transduction therapy. A novel approach to disease management

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7 January 2021

Targeting signal transduction for disease therapy

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7 January 2021

Tyrosine kinase inhibition: an approach to drug development

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7 January 2021

Tyrosine kinase inhibition ameliorates the hyperdynamic state and decreases nitric oxide production in cirrhotic rats with portal hypertension and ascites

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7 January 2021

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

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7 January 2021

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

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7 January 2021

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases

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7 January 2021

Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors

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7 January 2021

Epidermal‐Growth‐Factor‐Dependent Activation of the Src‐Family Kinases

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7 January 2021

Specific Inhibition of Insulin-Like Growth Factor-1 and Insulin Receptor Tyrosine Kinase Activity and Biological Function by Tyrphostins

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7 January 2021

The pathogenesis of atherosclerosis--an update

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7 January 2021

The pathogenesis of atherosclerosis (first of two parts)

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7 January 2021

Tyrphostin AG 556 improves survival and reduces multiorgan failure in canine Escherichia coli peritonitis.

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7 January 2021

Crystal structure of the Src family tyrosine kinase Hck

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7 January 2021

Tyrosine kinase inhibitors. 9. Synthesis and evaluation of fused tricyclic quinazoline analogues as ATP site inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor

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7 January 2021

4-(Phenylamino)pyrrolopyrimidines: potent and selective, ATP site directed inhibitors of the EGF-receptor protein tyrosine kinase

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7 January 2021

Late administration of a lipophilic tyrosine kinase inhibitor prevents lipopolysaccharide and Escherichia coli-induced lethal toxicity

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7 January 2021

Epidermal growth factor receptor tyrosine kinase. Investigation of catalytic mechanism, structure-based searching and discovery of a potent inhibitor

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7 January 2021

Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors

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7 January 2021

10.1016/S0163-7258(98)00066-7

Identifiers

DOI

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28 July 2017

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