(Q33685190)

28 July 2017

title

A free-energy perturbation study of the binding of methotrexate to mutants of dihydrofolate reductase (English)

1 reference

28 July 2017

1 reference

U C Singh

1

1 reference

28 July 2017

S J Benkovic

series ordinal

2

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28 July 2017

language of work or name

English

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publication date

1 December 1988

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28 July 2017

number of pages

5

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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28 July 2017

volume

85

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28 July 2017

issue

24

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28 July 2017

page(s)

9519-9523

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Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=282785

Recent progress in the medicinal chemistry of 2,4-diaminopyrimidines

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=282785

Functional role of aspartic acid-27 in dihydrofolate reductase revealed by mutagenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=282785

Probing the salt bridge in the dihydrofolate reductase-methotrexate complex by using the coordinate-coupled free-energy perturbation method

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=282785

Evaluation of the importance of hydrophobic interactions in drug binding to dihydrofolate reductase.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=282785

Identification of the 1 H resonances of valine and leucine residues in dihydrofolate reductase by using a combination of selective deuteration and two-dimensional correlation spectroscopy

14 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/3200837

12 December 2020

inferred from PubMed ID database lookup

Dihydrofolate reductase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/3200837

12 December 2020

inferred from PubMed ID database lookup

Calculation of the relative change in binding free energy of a protein-inhibitor complex

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/3200837

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.85.24.9519

1 reference

release_fwaxcogecvez7b7ayjcuk2t6hu

28 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fwaxcogecvez7b7ayjcuk2t6hu

24 November 2022

mapped directly with Wikidata item

PMC publication ID

282785

1 reference

28 July 2017

1 reference