(Q33647307)

28 July 2017

title

GSK4112, a Small Molecule Chemical Probe for the Cell Biology of the Nuclear Heme Receptor Rev-erbα (English)

1 reference

14 June 2024

1 reference

9

Timothy M. Willson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20677822

14 June 2024

author name string

Daniel Grant

1

1 reference

28 July 2017

Lei Yin

2

1 reference

28 July 2017

Shree Joshi

7

1 reference

28 July 2017

Jon L. Collins

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20677822

14 June 2024

Derek J. Parks

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20677822

14 June 2024

Lisa A. Orband-Miller

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20677822

14 June 2024

G. Bruce Wisely

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20677822

14 June 2024

Mitchell A. Lazar

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20677822

14 June 2024

William J. Zuercher

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20677822

14 June 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20677822

14 June 2024

publication date

1 October 2010

1 reference

28 July 2017

15 October 2010

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20677822

full work available at URL

14 June 2024

https://pubs.acs.org/doi/pdf/10.1021/cb100141y

1 reference

14 June 2024

1 reference

28 July 2017

volume

5

1 reference

28 July 2017

issue

10

1 reference

28 July 2017

page(s)

925-932

1 reference

Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism

28 July 2017

cites work

1

1 reference

Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta

14 June 2024

2

1 reference

Structural insight into the constitutive repression function of the nuclear receptor Rev-erbbeta

14 June 2024

4

1 reference

Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways

14 June 2024

5

1 reference

Identification of Rev-erbalpha as a physiological repressor of apoC-III gene transcription

14 June 2024

6

1 reference

Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors

14 June 2024

7

1 reference

Glucose-6-phosphatase catalytic subunit gene family

14 June 2024

8

1 reference

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

14 June 2024

9

1 reference

Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines

14 June 2024

10

1 reference

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

14 June 2024

11

1 reference

Circadian rhythms: mechanisms and therapeutic implications

14 June 2024

12

1 reference

The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

14 June 2024

13

1 reference

The nuclear receptor superfamily: the second decade

14 June 2024

14

1 reference

The Drosophila nuclear receptor e75 contains heme and is gas responsive

14 June 2024

15

1 reference

Drosophila nuclear receptor E75 is a thiolate hemoprotein.

14 June 2024

16

1 reference

Nuclear receptors homo sapiens Rev-erbbeta and Drosophila melanogaster E75 are thiolate-ligated heme proteins which undergo redox-mediated ligand switching and bind CO and NO.

14 June 2024

17

1 reference

Ligand modulation of REV-ERBalpha function resets the peripheral circadian clock in a phasic manner

14 June 2024

18

1 reference

Oxygen therapeutics: can we tame haemoglobin?

14 June 2024

19

1 reference

Non-specific inhibition of human cytochrome P450-catalyzed reactions by hemin

14 June 2024

20

1 reference

Selection, application, and validation of a set of molecular descriptors for nuclear receptor ligands.

14 June 2024

21

1 reference

The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene

14 June 2024

22

1 reference

The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeat

14 June 2024

23

1 reference

Physiological significance of a peripheral tissue circadian clock

14 June 2024

24

1 reference

Negative feedback maintenance of heme homeostasis by its receptor, Rev-erbalpha

14 June 2024

25

1 reference

The art of the chemical probe

14 June 2024

26

1 reference

Regulation of adipogenesis by natural and synthetic REV-ERB ligands.

14 June 2024

27

1 reference

Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha

14 June 2024

28

1 reference

14 June 2024

Identifiers

DOI

10.1021/CB100141Y

1 reference

28 July 2017

1 reference