(Q33604129)

28 July 2017

1 reference

title

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer (English)

1 reference

28 July 2017

1 reference

R J DeBerardinis

1

1 reference

28 July 2017

T Cheng

series ordinal

2

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28 July 2017

language of work or name

English

0 references

publication date

2 November 2009

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28 July 2017

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28 July 2017

volume

29

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28 July 2017

issue

3

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28 July 2017

page(s)

313-324

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Mechanisms of cancer cachexia

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Control of mammalian gene expression by amino acids, especially glutamine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Bidirectional transport of amino acids regulates mTOR and autophagy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Interorgan ammonia trafficking in liver disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Is cancer a disease of abnormal cellular metabolism? New angles on an old idea

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Tumor cell metabolism: cancer's Achilles' heel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Brick by brick: metabolism and tumor cell growth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Metabolic regulation of manganese superoxide dismutase expression via essential amino acid deprivation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

The x(c)- cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Molecular mechanisms contributing to glutamine-mediated intestinal cell survival

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Immune and cell modulation by amino acids

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Hypoxia upregulates amino acid transport in a human neuroblastoma cell line

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glutamine, insulin and glucocorticoids regulate glutamine synthetase expression in C2C12 myotubes, Hep G2 hepatoma cells and 3T3 L1 adipocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Amino acid limitation induces expression of ATF5 mRNA at the post-transcriptional level

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Molecular mechanisms of renal ammonia transport.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glutamine or glucose starvation in hybridoma cultures induces death receptor and mitochondrial apoptotic pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

p53 regulates mitochondrial respiration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glutamine pretreatment reduces IL-8 production in human intestinal epithelial cells by limiting IkappaBalpha ubiquitination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glutathione in cancer biology and therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Oxidative stress is not required for the induction of apoptosis upon glutamine starvation of Sp2/0-Ag14 hybridoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Molecular pathways leading to cancer cachexia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Pyruvate kinase type M2 and its role in tumor growth and spreading

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Expression of angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 is highly responsive to ambient glutamine availability: role of nuclear factor-kappaB and activating protein-1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Akt stimulates aerobic glycolysis in cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Cancer metabolism: facts, fantasy, and fiction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

On respiratory impairment in cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Targeting HIF-1 for cancer therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glucocorticoid induced expression of glutamine synthetase in hepatoma cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glutamate signalling in non-neuronal tissues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Inhibition of glutaminase expression by antisense mRNA decreases growth and tumourigenicity of tumour cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Determination of glutamine in muscle protein facilitates accurate assessment of proteolysis and de novo synthesis-derived endogenous glutamine production

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glutamine deprivation induces the expression of GADD45 and GADD153 primarily by mRNA stabilization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Therapeutic considerations of L-glutamine: a review of the literature

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Induction of gadd153 mRNA by nutrient deprivation is overcome by glutamine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

c-Myc transactivation of LDH-A: implications for tumor metabolism and growth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

L-glutamine and L-asparagine stimulate ODC activity and proliferation in a porcine jejunal enterocyte line

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Mitochondrial metabolism of glutamine and glutamate and its physiological significance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glutaminase activities and growth rates of rat hepatomas.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glutamine metabolism in lymphocytes: its biochemical, physiological and clinical importance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glutamine metabolism in the avian host bearing transplantable hepatomatous growth induced by MC-29 virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glutamine and glucose metabolism during thymocyte proliferation. Pathways of glutamine and glutamate metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Enzymic and metabolic adaptations in the gastrocnemius, plantaris and soleus muscles of hypocaloric rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Relevance of glutamine metabolism to tumor cell growth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Aerobic glycolysis during lymphocyte proliferation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Antisense glutaminase inhibition modifies the O-GlcNAc pattern and flux through the hexosamine pathway in breast cancer cells.

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

The effect of glutamine on radiation-induced organ damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Hypoxia regulates glutamate metabolism and membrane transport in rat PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Metabotropic glutamate receptors: new targets for the control of tumor growth?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Metabotropic glutamate receptor subtype-1 is essential for in vivo growth of melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Inhibition of glutaminase expression increases Sp1 phosphorylation and Sp1/Sp3 transcriptional activity in Ehrlich tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Glutamate release promotes growth of malignant gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Ketone body, glucose, lactic acid, and amino acid utilization by tumors in vivo in fasted rats

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Glucose metabolism in cachectic patients with colorectal cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Ammonia uptake in inactive muscles during exercise in humans

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809806

Intracellular free amino acid concentration in human muscle tissue

30 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Influence of progressive tumor growth on glutamine metabolism in skeletal muscle and kidney

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Nutrition needs of mammalian cells in tissue culture

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Adaptive cellular mechanisms in response to glutamine-starvation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Glutamine-enriched diets support muscle glutamine metabolism without stimulating tumor growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Effect of anaerobiosis and addition of keto acids on glutamine utilization by Ehrlich ascites-tumor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

The effect of tumour bearing on skeletal muscle glutamine metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

über den Stoffwechsel der Carcinomzelle

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.358

The proportionality of glutaminase content to growth rate and morphology of rat neoplasms

31 March 2020

1 reference

12 December 2020

Amino acid, glucose, and lactic acid utilization in vivo by rat tumors

1 reference

12 December 2020

Contribution by host tissues to circulating glutamine in mice inoculated with Ehrlich ascites tumor cells

1 reference

12 December 2020

L-glutamine stimulates intestinal cell proliferation and activates mitogen-activated protein kinases

1 reference

12 December 2020

Glycolytic activity in vivo of the mouse Ehrlich ascites tumor

1 reference

12 December 2020

Identifiers

DOI

10.1038/ONC.2009.358

1 reference

Dimensions Publication ID

28 July 2017

1041066726

0 references

Fatcat ID

release_xo5yxfnzsfegbpiwbow3ioj5ai

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xo5yxfnzsfegbpiwbow3ioj5ai

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2809806

1 reference

28 July 2017

1 reference