(Q33193594)

English

High Affinity Agonistic Metal Ion Binding Sites within the Melanocortin 4 Receptor Illustrate Conformational Change of Transmembrane Region 3

scientific article published on September 30, 2003

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Europe PubMed Central

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23 July 2017

High Affinity Agonistic Metal Ion Binding Sites within the Melanocortin 4 Receptor Illustrate Conformational Change of Transmembrane Region 3 (English)

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10.1074/JBC.M307683200

https://api.crossref.org/works/10.1074/JBC.M307683200

17 March 2024

transmembrane protein

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1 reference

10.1074/JBC.M307683200

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17 March 2024

1 reference

10.1074/JBC.M307683200

https://api.crossref.org/works/10.1074/JBC.M307683200

17 March 2024

Helgi B. Schiöth

8

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Helgi B Schiöth

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Europe PubMed Central

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23 July 2017

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Janis Klovins

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14523020

17 March 2024

Robert Fredriksson

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Robert Fredriksson

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14523020

17 March 2024

Davids Fridmanis

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Davids Fridmanis

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17 March 2024

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Tatjana Haitina

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23 July 2017

Malin C. Lagerström

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14523020

17 March 2024

Maria K. Ling

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Europe PubMed Central

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17 March 2024

Magnus M. Berglund

7

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17 March 2024

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publication date

30 September 2003

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23 July 2017

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http://www.jbc.org/content/278/51/51521.full.pdf

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17 March 2024

https://api.elsevier.com/content/article/PII:S0021925820754153?httpAccept=text/xml

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10.1074/JBC.M307683200

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17 March 2024

https://api.elsevier.com/content/article/PII:S0021925820754153?httpAccept=text/plain

1 reference

10.1074/JBC.M307683200

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17 March 2024

https://syndication.highwire.org/content/doi/10.1074/jbc.M307683200

1 reference

10.1074/JBC.M307683200

https://api.crossref.org/works/10.1074/JBC.M307683200

17 March 2024

Journal of Biological Chemistry

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Europe PubMed Central

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23 July 2017

278

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Europe PubMed Central

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23 July 2017

51

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Europe PubMed Central

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23 July 2017

51521-51526

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Metal-ion sites as structural and functional probes of helix-helix interactions in 7TM receptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Construction of a high affinity zinc switch in the kappa-opioid receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

One melanocortin 4 and two melanocortin 5 receptors from zebrafish show remarkable conservation in structure and pharmacology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Molecular determinants of ligand binding to the human melanocortin-4 receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Molecular determinants of human melanocortin-4 receptor responsible for antagonist SHU9119 selective activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Metal ion-mediated agonism and agonist enhancement in melanocortin MC1 and MC4 receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Interaction of metal ions with carboxylic and carboxamide groups in protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Association of feather colour with constitutively active melanocortin 1 receptors in chicken

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Modeling of the three-dimensional structure of the human melanocortin 1 receptor, using an automated method and docking of a rigid cyclic melanocyte-stimulating hormone core peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

The Role of a Conserved Region of the Second Intracellular Loop in AT1 Angiotensin Receptor Activation and Signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Mutagenesis and modelling of the alpha(1b)-adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Rhodopsin mutants that bind but fail to activate transducin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Projection structure of rhodopsin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Partial agonism through a zinc-Ion switch constructed between transmembrane domains III and VII in the tachykinin NK(1) receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Melanocortins and reproduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307683200

21 January 2018

Structural Biology of Zinc

8

1 reference

10.1074/JBC.M307683200

https://api.crossref.org/works/10.1074/JBC.M307683200

17 March 2024

Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): evaluation in vitro and in vivo.

11

1 reference

10.1074/JBC.M307683200

https://api.crossref.org/works/10.1074/JBC.M307683200

17 March 2024

Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants

15

1 reference

10.1074/JBC.M307683200

https://api.crossref.org/works/10.1074/JBC.M307683200

17 March 2024

Molecular Pharmacology

24

57

890

author name string

Alewijnse

publication date

2000

1 reference

10.1074/JBC.M307683200

https://api.crossref.org/works/10.1074/JBC.M307683200

17 March 2024

Molecular Pharmacology

25

57

219

author name string

Scheer

publication date

2000

1 reference

10.1074/JBC.M307683200

https://api.crossref.org/works/10.1074/JBC.M307683200

17 March 2024

Identifying conformational changes with site-directed spin labeling

31

1 reference

10.1074/JBC.M307683200

https://api.crossref.org/works/10.1074/JBC.M307683200

17 March 2024

Identifiers

10.1074/JBC.M307683200

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

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