(Q31530974)

2 July 2017

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title

DNA methylation: past, present and future directions (English)

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2 July 2017

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Robertson KD

1

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2 July 2017

Jones PA

series ordinal

2

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2 July 2017

language of work or name

English

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publication date

1 March 2000

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2 July 2017

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2 July 2017

volume

21

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2 July 2017

issue

3

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2 July 2017

page(s)

461-467

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The essentials of DNA methylation

2 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Cytosine methylation and the fate of CpG dinucleotides in vertebrate genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Role for DNA methylation in genomic imprinting

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Transcription of IAP endogenous retroviruses is constrained by cytosine methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21 WAF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

DNA methylation and genetic instability in colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

DNA hypomethylation leads to elevated mutation rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Demethylation of DNA by purified chick embryo 5-methylcytosine-DNA glycosylase requires both protein and RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

A mammalian protein with specific demethylase activity for mCpG DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Multiple new phenotypes induced in and 3T3 cells treated with 5-azacytidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Altering gene expression with 5-azacytidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Cancer epigenetics comes of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Effects of DNA methylation on DNA-binding proteins and gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Inactive chromatin spreads from a focus of methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

CpG islands in vertebrate genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Suppression of intestinal neoplasia by DNA hypomethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

The CpG dinucleotide and human genetic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hot spot in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

5-Methylcytosine is not a mutation hot spot in nondividing Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

High frequency mutagenesis by a DNA methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

A mutant HpaII methyltransferase functions as a mutator enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Purification of PCNA as a nucleotide excision repair protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

p53 function and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Hypermethylation of telomere-like foldbacks at codon 12 of the human c-Ha-ras gene and the trinucleotide repeat of the FMR-1 gene of fragile X.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

How does DNA methylation repress transcription?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Targeting chromatin disruption: Transcription regulators that acetylate histones

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Baculovirus-mediated expression and characterization of the full-length murine DNA methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Mechanistic aspects of genome-wide demethylation in the preimplantation mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

The p16INK4a/CDKN2A tumor suppressor and its relatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.3.461

21 January 2018

Identifiers

DOI

10.1093/CARCIN/21.3.461

1 reference

release_rfauvq7ydrd4nnzers3nbsvtqi

2 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rfauvq7ydrd4nnzers3nbsvtqi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference