(Q30728811)

26 June 2017

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title

Gene-trap mutagenesis: past, present and beyond (English)

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26 June 2017

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Stanford WL

1

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26 June 2017

Cohn JB

series ordinal

2

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26 June 2017

Cordes SP

series ordinal

3

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26 June 2017

publication date

1 October 2001

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26 June 2017

published in

Nature Reviews Genetics

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26 June 2017

volume

2

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26 June 2017

issue

10

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26 June 2017

page(s)

756-768

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Mouse models of human disease. Part I: techniques and resources for genetic analysis in mice

26 June 2017

cites work

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7 January 2021

Mouse models of human disease. Part II: recent progress and future directions

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7 January 2021

Hypervariable yellow (Ahvy), a new murine agouti mutation: Ahvy displays the largest variation in coat color phenotypes of all known agouti alleles

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7 January 2021

Neomorphic agouti mutations in obese yellow mice

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7 January 2021

Chlorambucil effectively induces deletion mutations in mouse germ cells

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7 January 2021

Specific-locus test shows ethylnitrosourea to be the most potent mutagen in the mouse

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7 January 2021

Capitalizing on large-scale mouse mutagenesis screens

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7 January 2021

Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus

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7 January 2021

Spontaneous germ line virus infection and retroviral insertional mutagenesis in eighteen transgenic Srev lines of mice

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7 January 2021

High frequency germline acquisition of ecotropic MuLV proviruses in SWR/J-RF/J hybrid mice

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7 January 2021

Introduction of a rabbit beta-globin gene into the mouse germ line

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7 January 2021

Integration and Stable Germ Line Transmission of Genes Injected into Mouse Pronuclei

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7 January 2021

Microinjection of cloned retroviral genomes into mouse zygotes: integration and expression in the animal.

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7 January 2021

The human beta-globin gene and a functional viral thymidine kinase gene in developing mice.

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7 January 2021

Targetted correction of a mutant HPRT gene in mouse embryonic stem cells

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7 January 2021

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

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7 January 2021

Targeted oncogene activation by site-specific recombination in transgenic mice

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7 January 2021

Tissue- and site-specific DNA recombination in transgenic mice

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7 January 2021

Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice

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7 January 2021

An SV40 “enhancer trap” incorporates exogenous enhancers or generates enhancers from its own sequences

1 reference

7 January 2021

Detection in situ of genomic regulatory elements in Drosophila

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7 January 2021

Transgenes as probes for active chromosomal domains in mouse development

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7 January 2021

A transgene containing lacZ inserted into the dystonia locus is expressed in neural tube.

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7 January 2021

Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes.

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7 January 2021

Enhancer trap integrations in mouse embryonic stem cells give rise to staining patterns in chimaeric embryos with a high frequency and detect endogenous genes

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7 January 2021

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice

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7 January 2021

Selective disruption of genes expressed in totipotent embryonal stem cells

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7 January 2021

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer

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7 January 2021

A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice

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7 January 2021

Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector

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7 January 2021

Gene trapping--a preface

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7 January 2021

An efficient gene-trap method using poly A trap vectors and characterization of gene-trap events

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7 January 2021

A new strategy of gene trapping in ES cells using 3'RACE

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7 January 2021

Efficient poly A trap approach allows the capture of genes specifically active in differentiated embryonic stem cells and in mouse embryos.

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7 January 2021

Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells

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7 January 2021

Functional genomics in mice by tagged sequence mutagenesis

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7 January 2021

Capturing genes encoding membrane and secreted proteins important for mouse development

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7 January 2021

Gene-trap-based target site for cre-mediated transgenic insertion

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7 January 2021

Loops, lineage, and leukemia

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7 January 2021

Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN

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7 January 2021

Genetic ablation: targeted expression of a toxin gene causes microphthalmia in transgenic mice.

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7 January 2021

Reversible immortalization of mammalian cells mediated by retroviral transfer and site-specific recombination

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7 January 2021

Functional analysis of secreted and transmembrane proteins critical to mouse development.

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7 January 2021

Defining brain wiring patterns and mechanisms through gene trapping in mice.

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7 January 2021

Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism

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7 January 2021

Generation of lymphohematopoietic cells from embryonic stem cells in culture

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7 January 2021

Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression

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7 January 2021

Endoderm-specific gene expression in embryonic stem cells differentiated to embryoid bodies.

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7 January 2021

Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells

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7 January 2021

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells

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7 January 2021

A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis

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7 January 2021

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

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7 January 2021

Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells

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7 January 2021

In vitro preselection of gene-trapped embryonic stem cell clones for characterizing novel developmentally regulated genes in the mouse

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7 January 2021

A gene trap strategy for identifying the gene expressed in the embryonic nervous system

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7 January 2021

An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro.

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7 January 2021

Aquarius, a novel gene isolated by gene trapping with an RNA-dependent RNA polymerase motif

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7 January 2021

Genes expressed after retinoic acid-mediated differentiation of embryoid bodies are likely to be expressed during embryo development.

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7 January 2021

An induction gene trap for identifying a homeoprotein-regulated locus.

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7 January 2021

Analysis of lipopolysaccharide-response genes in B-lineage cells demonstrates that they can have differentiation stage-restricted expression and contain SH2 domains.

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7 January 2021

Identification of genes induced by factor deprivation in hematopoietic cells undergoing apoptosis using gene-trap mutagenesis and site-specific recombination

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7 January 2021

Gene trapping identifies inhibitors of oncogenic transformation. The tissue inhibitor of metalloproteinases-3 (TIMP3) and collagen type I alpha2 (COL1A2) are epidermal growth factor-regulated growth repressors

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7 January 2021

Identification of a series of transforming growth factor beta-responsive genes by retrovirus-mediated gene trap screening

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7 January 2021

Gene trapping methods for the identification and functional analysis of cell surface proteins in mice

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7 January 2021

Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice

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7 January 2021

Sequence interpretation. Functional annotation of mouse genome sequences

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7 January 2021

An LDL-receptor-related protein mediates Wnt signalling in mice

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7 January 2021

Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice

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7 January 2021

A gene trap vector system for identifying transcriptionally responsive genes.

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7 January 2021

Creation of genome-wide protein expression libraries using random activation of gene expression

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7 January 2021

Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity

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7 January 2021

Insertion of retrovirus into the first intron of alpha 1(I) collagen gene to embryonic lethal mutation in mice

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7 January 2021

Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 locus leads to early embryonic death

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7 January 2021

Evidence for the stochastic integration of gene trap vectors into the mouse germline

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7 January 2021

Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

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7 January 2021

Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells

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7 January 2021

P-element-mediated enhancer detection: a versatile method to study development in Drosophila.

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7 January 2021

P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila

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7 January 2021

Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector

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7 January 2021

Organ-dependent regulation of a plant promoter isolated from rice by 'promoter-trapping' in tobacco

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7 January 2021

Technical advance: a high throughput system for transposon tagging and promoter trapping in tomato

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7 January 2021

A large-scale insertional mutagenesis screen in zebrafish

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7 January 2021

Identifiers

DOI

10.1038/35093548

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Dimensions Publication ID

26 June 2017

1039795303

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