(Q30499663)

17 October 2017

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome (English)

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17 October 2017

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1 reference

7

Ricardo E Dolmetsch

1 reference

17 October 2017

6

Joachim Hallmayer

1 reference

17 October 2017

Masayuki Yazawa

1

1 reference

17 October 2017

Brian Hsueh

series ordinal

2

1 reference

17 October 2017

Xiaolin Jia

series ordinal

3

1 reference

17 October 2017

Anca M. Pasca

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21307850

24 November 2024

Jonathan A. Bernstein

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21307850

24 November 2024

language of work or name

English

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publication date

9 February 2011

1 reference

full work available at URL

17 October 2017

https://europepmc.org/articles/pmc3077925?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21307850

https://europepmc.org/articles/PMC3077925

24 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21307850

https://europepmc.org/articles/PMC3077925?pdf=render

24 November 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21307850

http://www.nature.com/articles/nature09855.pdf

24 November 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/NATURE09855

http://www.nature.com/articles/nature09855

24 November 2024

1 reference

https://api.crossref.org/works/10.1038/NATURE09855

24 November 2024

1 reference

17 October 2017

471

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17 October 2017

7337

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17 October 2017

230-234

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describes a project that uses

17 October 2017

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Patient-specific induced pluripotent stem-cell models for long-QT syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Roscovitine binds to novel L-channel (CaV1.2) sites that separately affect activation and inactivation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Functional cardiomyocytes derived from human induced pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

The Timothy syndrome mutation of cardiac CaV1.2 (L-type) channels: multiple altered gating mechanisms and pharmacological restoration of inactivation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Proarrhythmic defects in Timothy syndrome require calmodulin kinase II.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Generation of pluripotent stem cells from adult mouse liver and stomach cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Clinical practice. Long-QT syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Mutation of an A-kinase-anchoring protein causes long-QT syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Induced pluripotent stem cell lines derived from human somatic cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Roscovitine, a cyclin-dependent kinase inhibitor, affects several gating mechanisms to inhibit cardiac L-type (Ca(V)1.2) calcium channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Genetics of acquired long QT syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Cardiotoxicity of new antihistamines and cisapride

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Sudden death due to cardiac arrhythmias

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Functional embryonic cardiomyocytes after disruption of the L-type alpha1C (Cav1.2) calcium channel gene in the mouse.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Formation of junctions involved in excitation-contraction coupling in skeletal and cardiac muscle.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

The long QT syndrome. A review of recent molecular genetic and physiologic discoveries

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

Ion Channels in Cardiac Cell Membranes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077925

TRIC channels are essential for Ca2+ handling in intracellular stores.

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE09855

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE09855

Wnt3a-induced mesoderm formation and cardiomyogenesis in human embryonic stem cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21307850

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Journal of Clinical Investigation

25

118

2246

M Brunner

2008

1 reference

https://api.crossref.org/works/10.1038/NATURE09855

24 November 2024

Identifiers

DOI

10.1038/NATURE09855

1 reference

Dimensions Publication ID

17 October 2017

0 references

1 reference

17 October 2017

1 reference