(Q30448380)

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Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner

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Europe PubMed Central

PMC publication ID

9 November 2017

Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner (English)

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

author name string

Yong Li

1

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

Mihwa Choi

2

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

Kelly Suino

3

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

Amanda Kovach

4

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

Jennifer Daugherty

5

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

Steven A Kliewer

6

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

H Eric Xu

7

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Europe PubMed Central

PMC publication ID

9 November 2017

language of work or name

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publication date

23 June 2005

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

number of pages

6

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inferred from page(s)

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

PMC publication ID

9 November 2017

102

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

27

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

9505-9510

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Identification of liver receptor homolog-1 as a novel regulator of apolipoprotein AI gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Molecular mechanism for the potentiation of the transcriptional activity of human liver receptor homolog 1 by steroid receptor coactivator-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Activation of nuclear receptors: a perspective from structural genomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Structural basis for ligand-independent activation of the orphan nuclear receptor LRH-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

The small heterodimer partner interacts with the pregnane X receptor and represses its transcriptional activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

LXXLL-related motifs in Dax-1 have target specificity for the orphan nuclear receptors Ad4BP/SF-1 and LRH-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Liver receptor homolog 1 controls the expression of the scavenger receptor class B type I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Glucocorticoid signaling is perturbed by the atypical orphan receptor and corepressor SHP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Steroidogenic factor 1: an essential mediator of endocrine development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Characterization of the interaction between androgen receptor and a new transcriptional inhibitor, SHP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Liver receptor homologue-1 is expressed in the adrenal and can regulate transcription of 11 beta-hydroxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Function of steroidogenic factor 1 during development and differentiation of the reproductive system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

The orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Activation of the promoter of the orphan receptor SHP by orphan receptors that bind DNA as monomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Inhibition of estrogen receptor action by the orphan receptor SHP (short heterodimer partner)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

20 June 2018

Inhibition of Estrogen Receptor Action by the Orphan Receptor SHP (Short Heterodimer Partner)

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501204102

21 January 2018

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501204102

21 January 2018

Relative helix-forming tendencies of nonpolar amino acids

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501204102

21 January 2018

Expression and regulation of transcripts encoding two members of the NR5A nuclear receptor subfamily of orphan nuclear receptors, steroidogenic factor-1 and NR5A2, in equine ovarian cells during the ovulatory process

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501204102

21 January 2018

Redundant pathways for negative feedback regulation of bile acid production

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0501204102

21 January 2018

The nuclear xenobiotic receptor CAR: structural determinants of constitutive activation and heterodimerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1157103

26 November 2018

Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976031

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0501204102

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

2005PNAS..102.9505L

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 November 2017

ResearchGate publication ID

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