(Q29817187)

English

DJ-1alpha Dmel_CG6646

Protein found in Drosophila melanogaster

CG6646-PA
DJ-1alpha
DJ-1alpha-PA
CG6646 gene product from transcript CG6646-RA
DJ-1A

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No label defined

No description defined

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Statements

1 reference

25 May 2022

Protein/nucleic acid deglycase DJ-1

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/A1Z9J4

Class I glutamine amidotransferase-like

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/A1Z9J4

DJ-1/PfpI domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

protein deglycase activity

determination method or standard

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9J4&geneProductId=UniProtKB:A1Z9J4

determination method or standard

ISS

oxidoreductase activity, acting on peroxide as acceptor

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

ISS

cell component

intracellular anatomical structure

determination method or standard

1 reference

27 March 2018

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9J4&geneProductId=UniProtKB:A1Z9J4

determination method or standard

IEA

mitochondrion

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

IEA

nucleus

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

IBA

cytosol

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

IBA

biological process

response to oxidative stress

determination method or standard

3 references

8 April 2019

Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

IMP

retrieved

8 April 2019

stated in

Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

IMP

retrieved

8 April 2019

stated in

Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

IDA

phosphatidylinositol 3-kinase signaling

determination method or standard

IGI

1 reference

retrieved

8 April 2019

stated in

Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

IGI

dopamine metabolic process

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

IMP

mitochondrial ATP synthesis coupled electron transport

determination method or standard

IGI

1 reference

retrieved

8 April 2019

stated in

DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

IGI

regulation of protein kinase B signaling

determination method or standard

IGI

IMP

neuron cellular homeostasis

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

IMP

protein deglycation

determination method or standard

1 reference

27 March 2018

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9J4&geneProductId=UniProtKB:A1Z9J4

determination method or standard

IEA

protein deglycation, glyoxal removal

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

IBA

guanine deglycation, glyoxal removal

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9J4

determination method or standard

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/A1Z9J4

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

(Q29817187)

DJ-1alpha Dmel_CG6646

Statements

Identifiers

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