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English
Tumor metastasis: mechanistic insights and clinical challenges
scientific article (publication date: August 2006)
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scholarly article
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review article
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Europe PubMed Central
title
Tumor metastasis: mechanistic insights and clinical challenges
(English)
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stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16892035
retrieved
30 April 2017
main subject
tumor metastasis
1 reference
based on heuristic
inferred from title
author name string
Steeg PS
series ordinal
1
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16892035
retrieved
30 April 2017
language of work or name
English
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16892035
retrieved
30 April 2017
publication date
August 2006
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16892035
retrieved
30 April 2017
published in
Nature Medicine
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16892035
retrieved
30 April 2017
volume
12
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16892035
retrieved
30 April 2017
issue
8
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16892035
retrieved
30 April 2017
page(s)
895-904
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16892035
retrieved
30 April 2017
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High expression of PRL-3 promotes cancer cell motility and liver metastasis in human colorectal cancer: a predictive molecular marker of metachronous liver and lung metastases
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Vascular endothelial growth factor expression promotes the growth of breast cancer brain metastases in nude mice
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Transforming growth factor-beta facilitates breast carcinoma metastasis by promoting tumor cell survival
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Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis
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7 January 2021
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A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth
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based on heuristic
inferred from DOI database lookup
DAP kinase links the control of apoptosis to metastasis
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The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer.
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Inhibition of anchorage-independent growth and lung metastasis of A549 lung carcinoma cells by IkappaBbeta
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inferred from DOI database lookup
Granulocytes mediates the Fas-L-associated apoptosis during lung metastasis of melanoma that determines the metastatic behaviour
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Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression
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Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1.
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based on heuristic
inferred from DOI database lookup
Metastasis-suppressed C8161 melanoma cells arrest in lung but fail to proliferate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metastasis suppressors alter the signal transduction of cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metastasis suppressor pathways--an evolving paradigm.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RhoGDI2 is an invasion and metastasis suppressor gene in human cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A molecular signature of metastasis in primary solid tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic background is an important determinant of metastatic potential.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene expression profiles of primary breast tumors maintained in distant metastases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular portraits of human breast tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pathogenesis of cancer metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Time distribution of the recurrence risk for breast cancer patients undergoing mastectomy: Further support about the concept of tumor dormancy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship between disease-free interval and survival in patients with recurrent melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dissecting the metastatic cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic significance of micrometastatic tumour cells in bone marrow of colorectal cancer patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Self-renewal and solid tumor stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stem cells, cancer, and cancer stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prospective identification of tumorigenic breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Therapeutic implications of cancer stem cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumour stem cells and drug resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selection with melphalan or paclitaxel (Taxol) yields variants with different patterns of multidrug resistance, integrin expression and in vitro invasiveness
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gefitinib (ZD1839, Iressa) in non-small-cell lung cancer: a review of clinical trials from a daily practice perspective.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epidermal growth factor receptor overexpression results in increased tumor cell motility in vivo coordinately with enhanced intravasation and metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of insulin receptor substrate 2 in mammary tumor metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antimetastatic effect of salvicine on human breast cancer MDA-MB-435 orthotopic xenograft is closely related to Rho-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-metastatic properties of RGD-peptidomimetic agents S137 and S247.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of alpha-difluoromethylornithine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low-dose irradiation and short-exposure suboptimal-dose paclitaxel adversely modulate metastatic potential of squamous carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Magnesium deficiency inhibits primary tumor growth but favors metastasis in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Maintenance therapy to suppress micrometastasis: the new challenge for adjuvant cancer treatment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Imaging angiogenesis: applications and potential for drug development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protease-activated quantum dot probes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The design of clinical trials for new molecularly targeted compounds: progress and new initiatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase I trial design for solid tumor studies of targeted, non-cytotoxic agents: theory and practice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM1469
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NM1469
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16892035
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1507324
Dimensions Publication ID
1020800104
0 references
OpenCitations bibliographic resource ID
1507324
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1507324
PubMed publication ID
16892035
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16892035
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1507324
ResearchGate publication ID
6895093
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