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Toll-like receptors: critical proteins linking innate and acquired immunity
scientific article (publication date: August 2001)
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title
Toll-like receptors: critical proteins linking innate and acquired immunity
(English)
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11477402
retrieved
30 April 2017
main subject
toll-like receptor
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author name string
Akira S
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1
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11477402
retrieved
30 April 2017
Takeda K
series ordinal
2
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PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11477402
retrieved
30 April 2017
Kaisho T
series ordinal
3
1 reference
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PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11477402
retrieved
30 April 2017
language of work or name
English
1 reference
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PubMed
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30 April 2017
publication date
August 2001
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PubMed
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retrieved
30 April 2017
published in
Nature Immunology
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11477402
retrieved
30 April 2017
volume
2
1 reference
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11477402
retrieved
30 April 2017
issue
8
1 reference
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11477402
retrieved
30 April 2017
page(s)
675-80
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stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11477402
retrieved
30 April 2017
cites work
Innate Immunity: The Virtues of a Nonclonal System of Recognition
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phylogenetic perspectives in innate immunity
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptors in the induction of the innate immune response
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
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Functional diversity of helper T lymphocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
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7 January 2021
based on heuristic
inferred from DOI database lookup
Toll signaling pathways in the innate immune response
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A family of human receptors structurally related to Drosophila Toll
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TLR6: A novel member of an expanding toll-like receptor family
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Toll-like receptor recognizes bacterial DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Toll-like receptors in human monocytes and dendritic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptor-2 mediates Treponema glycolipid and lipoteichoic acid-induced NF-kappaB translocation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Discrimination of bacterial lipoproteins by Toll-like receptor 6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: I kappa B alpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Causing a commotion in the blood: immunotherapy progresses from bacteria to bacterial DNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-PKcs is required for activation of innate immunity by immunostimulatory DNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The product of the tobacco mosaic virus resistance gene N: similarity to toll and the interleukin-1 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An innate sense of danger
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oligosaccharides of hyaluronan are potent activators of dendritic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phenotypic and Functional Maturation of Dendritic Cells Mediated by Heparan Sulfate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The extra domain A of fibronectin activates Toll-like receptor 4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Unresponsiveness of MyD88-deficient mice to endotoxin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NEMO/IKK gamma-deficient mice model incontinentia pigmenti.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JNK2 and IKKbeta are required for activating the innate response to viral infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The dendritic cell system and its role in immunogenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dendritic cells and the control of immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of dendritic cells in the induction and regulation of immunity to microbial infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dendritic cell regulation of TH1-TH2 development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulating the immune response with dendritic cells and their growth factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dendritic cell lineage, plasticity and cross-regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bacterial CpG-DNA triggers activation and maturation of human CD11c-, CD123+ dendritic cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endotoxin-induced maturation of MyD88-deficient dendritic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct CpG DNA and polyinosinic-polycytidylic acid double-stranded RNA, respectively, stimulate CD11c- type 2 dendritic cell precursors and CD11c+ dendritic cells to produce type I IFN
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of direct antimicrobial activity through mammalian toll-like receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F90609
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/90609
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11477402
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
627315
OpenCitations bibliographic resource ID
627315
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
627315
PubMed publication ID
11477402
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11477402
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
627315
ResearchGate publication ID
11866195
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