(Q29615030)

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Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

scientific article (publication date: August 2002)

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Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia (English)

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12204532

30 April 2017

chronic myeloid leukemia

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author name string

Shah NP

1

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12204532

30 April 2017

Nicoll JM

2

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12204532

30 April 2017

Nagar B

3

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12204532

30 April 2017

Gorre ME

4

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12204532

30 April 2017

Paquette RL

5

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12204532

30 April 2017

Kuriyan J

6

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12204532

30 April 2017

Sawyers CL

7

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30 April 2017

language of work or name

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30 April 2017

publication date

August 2002

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30 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12204532

30 April 2017

2

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12204532

30 April 2017

2

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30 April 2017

117-25

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12204532

30 April 2017

An activating mutation in the ATP binding site of the ABL kinase domain.

1 reference

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7 January 2021

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Roots of clinical resistance to STI-571 cancer therapy

1 reference

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7 January 2021

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High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance

1 reference

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Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

1 reference

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7 January 2021

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Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

1 reference

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7 January 2021

based on heuristic

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Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

1 reference

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Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

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bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

1 reference

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SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

1 reference

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based on heuristic

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Role of alpha1 acid glycoprotein in the in vivo resistance of human BCR-ABL(+) leukemic cells to the abl inhibitor STI571

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900096-X

7 January 2021

based on heuristic

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Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900096-X

7 January 2021

based on heuristic

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Ph(+) acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900096-X

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Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

1 reference

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Alpha1-acid glycoprotein expressed in the plasma of chronic myeloid leukemia patients does not mediate significant in vitro resistance to STI571.

1 reference

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based on heuristic

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Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia

1 reference

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Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

1 reference

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Functional interaction between DNA-PK and c-Abl in response to DNA damage

1 reference

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Increase in mutant frequencies in mice expressing the BCR-ABL activated tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900096-X

7 January 2021

based on heuristic

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Chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900096-X

7 January 2021

based on heuristic

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Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900096-X

7 January 2021

based on heuristic

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Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900096-X

7 January 2021

based on heuristic

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Interaction between ATM protein and c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900096-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900096-X

7 January 2021

based on heuristic

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BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900096-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900096-X

7 January 2021

based on heuristic

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c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900096-X

7 January 2021

based on heuristic

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