(Q28679171)

6 February 2017

title

Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways (English)

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6 February 2017

main subject

4',5-dihydroxydiclofenac

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ChEBI release 2020-05-28

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ChEBI release 2020-05-28

R. Bort

1

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6 February 2017

K. Macé

2

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6 February 2017

A. Boobis

3

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6 February 2017

M. J. Gómez-Lechón

4

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6 February 2017

A. Pfeifer

5

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6 February 2017

J. Castell

6

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6 February 2017

language of work or name

English

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publication date

1 September 1999

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6 February 2017

published in

Biochemical Pharmacology

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6 February 2017

volume

58

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6 February 2017

issue

5

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6 February 2017

page(s)

787–796

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Diclofenac induced hepatitis. 3 cases with features of autoimmune chronic active hepatitis

6 February 2017

cites work

1 reference

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7 January 2021

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Oxidation of diclofenac to reactive intermediates by neutrophils, myeloperoxidase, and hypochlorous acid

7 January 2021

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Cytochrome P450TB (CYP2C): a major monooxygenase catalyzing diclofenac 4'-hydroxylation in human liver

7 January 2021

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Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes

7 January 2021

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Culture of human hepatocytes from small surgical liver biopsies. Biochemical characterization and comparison with in vivo

7 January 2021

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Simian virus 40 large tumor antigen-immortalized normal human liver epithelial cells express hepatocyte characteristics and metabolize chemical carcinogens

7 January 2021

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Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450- expressing human liver cell lines

7 January 2021

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7 January 2021

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Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens

7 January 2021

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7 January 2021

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7 January 2021

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Interaction of sulfaphenazole derivatives with human liver cytochromes P450 2C: molecular origin of the specific inhibitory effects of sulfaphenazole on CYP 2C9 and consequences for the substrate binding site topology of CYP 2C9

7 January 2021

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7 January 2021

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Evaluation of triacetyloleandomycin, alpha-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450.

7 January 2021

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Validation and use of cloned, expressed human drug-metabolizing enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactions

7 January 2021

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Pharmacokinetics and Metabolism of the Anti-Inflammatory Agent Voltaren

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(99)00167-7

0 references

1 reference