(Q28588821)

31 January 2017

title

Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy (English)

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hypertrophic cardiomyopathy

31 January 2017

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GOA release 2020-03-11

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1 reference

J. C. Tardiff

1

1 reference

31 January 2017

T. E. Hewett

2

1 reference

31 January 2017

B. M. Palmer

3

1 reference

31 January 2017

C. Olsson

4

1 reference

31 January 2017

S. M. Factor

5

1 reference

31 January 2017

R. L. Moore

6

1 reference

31 January 2017

J. Robbins

7

1 reference

31 January 2017

L. A. Leinwand

8

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31 January 2017

language of work or name

English

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publication date

1 August 1999

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Journal of Clinical Investigation

31 January 2017

published in

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31 January 2017

volume

104

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31 January 2017

issue

4

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31 January 2017

page(s)

469–481

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Troponin T: genetics, properties and function

31 January 2017

cites work

1 reference

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A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy

17 March 2017

1 reference

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Diastolic dysfunction and altered energetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy

17 March 2017

1 reference

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Expression of a mutant (Arg92Gln) human cardiac troponin T, known to cause hypertrophic cardiomyopathy, impairs adult cardiac myocyte contractility

17 March 2017

1 reference

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Sudden death due to troponin T mutations

17 March 2017

1 reference

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Codon 102 of the cardiac troponin T gene is a putative hot spot for mutations in familial hypertrophic cardiomyopathy

17 March 2017

1 reference

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Altered cardiac troponin T in vitro function in the presence of a mutation implicated in familial hypertrophic cardiomyopathy

17 March 2017

1 reference

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A mouse model of familial hypertrophic cardiomyopathy

17 March 2017

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Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere

17 March 2017

1 reference

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Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy

17 March 2017

1 reference

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Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

17 March 2017

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

17 March 2017

2 references

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17 March 2017

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Functional analyses of troponin T mutations that cause hypertrophic cardiomyopathy: insights into disease pathogenesis and troponin function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408522

Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy.

29 September 2017

1 reference

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Dominant-negative effect of a mutant cardiac troponin T on cardiac structure and function in transgenic mice

29 September 2017

1 reference

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Functional analysis of the mutations in the human cardiac beta-myosin that are responsible for familial hypertrophic cardiomyopathy. Implication for the clinical outcome

29 September 2017

1 reference

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Expression and functional assessment of a truncated cardiac troponin T that causes hypertrophic cardiomyopathy. Evidence for a dominant negative action

29 September 2017

1 reference

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Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy

29 September 2017

1 reference

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Thin filament-mediated regulation of cardiac contraction

29 September 2017

1 reference

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Familial hypertrophic cardiomyopathy: a genetic model of cardiac hypertrophy

29 September 2017

1 reference

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Hypertrophic cardiomyopathy — pathology and pathogenesis

29 September 2017

1 reference

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Hypertrophic cardiomyopathy. Interrelations of clinical manifestations, pathophysiology, and therapy (1).

29 September 2017

1 reference

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Hypertrophic cardiomyopathy: current views on etiology, pathophysiology, and management

29 September 2017

1 reference

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Ultrastructural features of degenerated cardiac muscle cells in patients with cardiac hypertrophy

29 September 2017

1 reference

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Hypertrophy, pathology, and molecular markers of cardiac pathogenesis.

29 September 2017

1 reference

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The role of cytoskeletal proteins in cardiomyopathies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408522

Various hypertrophic stimuli induce distinct phenotypes in cardiomyocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408522

Low power, type II errors, and other statistical problems in recent cardiovascular research

3 June 2018

1 reference

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Characterization of the mouse beta maj globin transcription termination region: a spacing sequence is required between the poly(A) signal sequence and multiple downstream termination elements

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408522

Heterologous expression of a cardiomyopathic myosin that is defective in its actin interaction

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408522

Early morphologic changes in cat heart muscle cells after acute coronary artery occlusion

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408522

Contractile deactivation and uncoupling of crossbridges. Effects of 2,3-butanedione monoxime on mammalian myocardium

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408522

Ischemic myocardial mitochondrial function and ultrastructural change--influence of regional myocardial blood flow

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408522

Ca2+-sensitizing effects of the mutations at Ile-79 and Arg-92 of troponin T in hypertrophic cardiomyopathy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408522

Transgenic remodeling of the regulatory myosin light chains in the mammalian heart

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408522

Electron microscopic investigation of endomyocardial biopsy samples in hypertrophy and cardiomyopathy. A semiquantitative study in 48 patients

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408522

Morphometric comparison of mitochondria and myofibrils of cardiomyocytes between hypertrophic and dilated cardiomyopathies

27 November 2018

1 reference

12 December 2020

Regional left ventricular mechanics in hypertrophic cardiomyopathy

1 reference

12 December 2020

Comparison of normal, hypodynamic, and hyperdynamic mouse hearts using isolated work-performing heart preparations

1 reference

12 December 2020

Hypertension alters rapid cooling contractures in single rat cardiocytes

1 reference

12 December 2020

The in vitro motility activity of beta-cardiac myosin depends on the nature of the beta-myosin heavy chain gene mutation in hypertrophic cardiomyopathy

1 reference

12 December 2020

Method for isolation of adult mouse cardiac myocytes for studies of contraction and microfluorimetry

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI6067

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