(Q28579792)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Matthew P. Jacobson

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

9

Diane L Barber

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

6

John Condeelis

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Christian Frantz

1

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Gabriela Barreiro

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Xiaoming Chen

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Robert Eddy

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Mark J S Kelly

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

24 November 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

published in

Journal of Cell Biology

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

183

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

5

2 references

31 January 2017

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17 January 2020

page(s)

865-879

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

Positive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cells

17 January 2020

cites work

1 reference

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The Amber biomolecular simulation programs

17 March 2017

1 reference

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Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics

17 March 2017

1 reference

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Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

17 March 2017

1 reference

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Solution structure of human cofilin: actin binding, pH sensitivity, and relationship to actin-depolymerizing factor

17 March 2017

1 reference

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Cellular motility driven by assembly and disassembly of actin filaments

17 March 2017

1 reference

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Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin

17 March 2017

1 reference

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Cofilin produces newly polymerized actin filaments that are preferred for dendritic nucleation by the Arp2/3 complex

17 March 2017

1 reference

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The Nck-interacting kinase (NIK) phosphorylates the Na+-H+ exchanger NHE1 and regulates NHE1 activation by platelet-derived growth factor

17 March 2017

1 reference

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Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Actin filaments are severed by both native and recombinant dictyostelium cofilin but to different extents

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission

17 March 2017

1 reference

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Localized depolymerization of the major sperm protein cytoskeleton correlates with the forward movement of the cell body in the amoeboid movement of nematode sperm

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Human actin depolymerizing factor mediates a pH-sensitive destruction of actin filaments

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy

17 March 2017

1 reference

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Regulation of actin filament assembly by Arp2/3 complex and formins

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

A hierarchical approach to all-atom protein loop prediction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

The ARP2/3 complex: an actin nucleator comes of age

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Exploring protein native states and large-scale conformational changes with a modified generalized born model

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Novel procedure for modeling ligand/receptor induced fit effects.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Protein complexes regulating Arp2/3-mediated actin assembly.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Stimulation of actin polymerization by filament severing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Targeting of the FYVE domain to endosomal membranes is regulated by a histidine switch

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Rac regulation of chemotaxis and morphogenesis in Dictyostelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Cofilin promotes actin polymerization and defines the direction of cell motility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Two phases of actin polymerization display different dependencies on PI(3,4,5)P3 accumulation and have unique roles during chemotaxis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Uniform cAMP stimulation of Dictyostelium cells induces localized patches of signal transduction and pseudopodia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Polarised migration: cofilin holds the front.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

ADF/cofilin and actin dynamics in disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Importance of free actin filament barbed ends for Arp2/3 complex function in platelets and fibroblasts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Spatial regulation of actin dynamics: a tropomyosin-free, actin-rich compartment at the leading edge

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Regulation of movement speed by intracellular pH during Dictyostelium discoideum chemotaxis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

How is actin polymerization nucleated in vivo?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Intracellular pH modulation of ADF/cofilin proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Phosphorylation of ADF/cofilin abolishes EGF-induced actin nucleation at the leading edge and subsequent lamellipod extension

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Na+/H+ exchanger-dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Polarization of Na(+)/H(+) and Cl(-)/HCO (3)(-) exchangers in migrating renal epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Phosphorylation of Ser-3 of cofilin regulates its essential function on actin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Syk tyrosine kinase is required for immunoreceptor tyrosine activation motif-dependent actin assembly

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Fluorescent actin filaments move on myosin fixed to a glass surface

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Identification of actin nucleation activity and polymerization inhibitor in ameboid cells: their regulation by chemotactic stimulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

pH regulates the polymerization of actin in the sea urchin egg cortex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Polymerization of actin. IV. Role of Ca++ and H+ in the assembly of actin and in membrane fusion in the acrosomal reaction of echinoderm sperm

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

A proposed mechanism for cell polarization with no external cues

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Role of phosphatidylinositol 3' kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

The competitive interaction of actin and PIP2 with actophorin is based on overlapping target sites: design of a gain-of-function mutant

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Effect of inhibitors of Na+/H+-exchange and gastric H+/K+ ATPase on cell volume, intracellular pH and migration of human polymorphonuclear leucocytes.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Interactions of ADF/cofilin, Arp2/3 complex, capping protein and profilin in remodeling of branched actin filament networks

3 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200804161

In vitro activity differences between proteins of the ADF/cofilin family define two distinct subgroups

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200804161

Integrin alpha(IIb)beta3 signals lead cofilin to accelerate platelet actin dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200804161

Mapping the Phosphoinositide-Binding Site on Chick Cofilin Explains How PIP2 Regulates the Cofilin-Actin Interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200804161

Cdc42 and PI(4,5)P2-induced actin assembly in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200804161

The effect of two actin depolymerizing factors (ADF/cofilins) on actin filament turnover : pH sensitivity of F-actin binding by human ADF, but not of Acanthamoeba actophorin

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200804161

Constant pH molecular dynamics in generalized Born implicit solvent

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200804161

Initiation of cofilin activity in response to EGF is uncoupled from cofilin phosphorylation and dephosphorylation in carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200804161

Backbone and sidechain 1H, 13C and 15N resonance assignments of human cofilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200804161

ADF/Cofilin Controls Cell Polarity during Fibroblast Migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200804161

Chemotaxis in the Absence of PIP3 Gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200804161

Identification of Yeast Cofilin Residues Specific for Actin Monomer and PIP2Binding†

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200804161

Inhibition of the interactions of cofilin, destrin, and deoxyribonuclease I with actin by phosphoinositides.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592832

Regulation of the Ascaris major sperm protein (MSP) cytoskeleton by intracellular pH

27 November 2018

1 reference

12 December 2020

Actin polymerization, calcium-transients, and phospholipid metabolism in human neutrophils after stimulation with interleukin-8 and N-formyl peptide

1 reference

12 December 2020

Oscillatory increases in alkalinity anticipate growth and may regulate actin dynamics in pollen tubes of lily

1 reference

12 December 2020

EGF stimulates an increase in actin nucleation and filament number at the leading edge of the lamellipod in mammary adenocarcinoma cells

1 reference

12 December 2020

Effect of phospholipase C-gamma overexpression on PDGF-induced second messengers and mitogenesis

1 reference

12 December 2020

[33] Assays for actin sliding movement over myosin-coated surfaces

1 reference

12 December 2020

Uncoupling actin filament fragmentation by cofilin from increased subunit turnover

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200804161

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029335%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

2 references