(Q28556322)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P21272

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

RNA polymerase II core promoter sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

DNA-binding transcription repressor activity, RNA polymerase II-specific

1 reference

14 February 2019

The CCAAT enhancer-binding protein (C/EBP)beta and Nrf1 interact to regulate dentin sialophosphoprotein (DSPP) gene expression during odontoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

C/EBP DNA-binding activity is upregulated by a glucocorticoid-dependent mechanism in septic muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

chromatin binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

DNA-binding transcription factor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

1 reference

14 February 2019

protein binding

3 references

14 February 2019

Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

Identification of heterogeneous nuclear ribonucleoprotein K (hnRNP K) as a repressor of C/EBPbeta-mediated gene activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

transcription factor binding

3 references

14 February 2019

Downregulation of cytochromes P450 in growth-stimulated rat hepatocytes: role of c-Myc induction and impaired C/EBP binding to DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

Transcriptional Co-activators CREB-binding protein/p300 increase chondrocyte Cd-rap gene expression by multiple mechanisms including sequestration of the repressor CCAAT/enhancer-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

kinase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

histone acetyltransferase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

glucocorticoid receptor binding

1 reference

14 February 2019

Association of the glucocorticoid receptor with STAT3, C/EBPbeta, and the hormone-responsive element within the rat haptoglobin gene promoter during the acute phase response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

protein homodimerization activity

CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

histone deacetylase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

ubiquitin-like protein ligase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

protein heterodimerization activity

CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

condensed chromosome, centromeric region

cell component

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

C/EBP DNA-binding activity is upregulated by a glucocorticoid-dependent mechanism in septic muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

nuclear matrix

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

Acute-phase-dependent binding affinity of C/EBPbeta from the nuclear extract and nuclear matrix towards the hormone response element of the alpha2-macroglobulin gene in rat hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

Solubility partitioning of C/EBPbeta on the rat hepatocyte nuclear matrix by hydrophobic interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

CHOP-C/EBP complex

1 reference

14 February 2019

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

RNA polymerase II transcription regulator complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

negative regulation of transcription by RNA polymerase II

biological process

1 reference

14 February 2019

The CCAAT enhancer-binding protein (C/EBP)beta and Nrf1 interact to regulate dentin sialophosphoprotein (DSPP) gene expression during odontoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

liver development

1 reference

14 February 2019

Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

embryonic placenta development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

14 February 2019

Acute-phase-dependent binding affinity of C/EBPbeta from the nuclear extract and nuclear matrix towards the hormone response element of the alpha2-macroglobulin gene in rat hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

IC

memory

1 reference

14 February 2019

Transthyretin: a key gene involved in the maintenance of memory capacities during aging

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

1 reference

14 February 2019

neuron differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

response to lipopolysaccharide

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

mammary gland epithelial cell proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

negative regulation of neuron apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

fat cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

positive regulation of osteoblast differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

negative regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

positive regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

positive regulation of inflammatory response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

brown fat cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

mammary gland epithelial cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

positive regulation of biomineral tissue development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

cellular response to lipopolysaccharide

1 reference

14 February 2019

Alzheimer amyloid-beta peptides block the activation of C/EBPbeta and C/EBPdelta in glial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

cellular response to amino acid stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

cellular response to interleukin-1

1 reference

14 February 2019

Alzheimer amyloid-beta peptides block the activation of C/EBPbeta and C/EBPdelta in glial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

cellular response to organic cyclic compound

1 reference

14 February 2019

Pro-bone and antifat effects of green tea and its polyphenol, epigallocatechin, in rat mesenchymal stem cells in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

regulation of odontoblast differentiation

1 reference

14 February 2019

The CCAAT enhancer-binding protein (C/EBP)beta and Nrf1 interact to regulate dentin sialophosphoprotein (DSPP) gene expression during odontoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

positive regulation of sodium-dependent phosphate transport

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

regulation of dendritic cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21272

Basic-leucine zipper domain

has part(s)

1 reference

InterPro Release 71.0