(Q28371622)

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Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and -independent pathways in ovarian cancer cells

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Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and -independent pathways in ovarian cancer cells (English)

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based on heuristic

inferred from title

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based on heuristic

inferred from title

apoptotic process

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based on heuristic

inferred from title

Hidenori Ichijō

object named as

H Ichijo

7

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author name string

T H Wang

1

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D M Popp

2

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H S Wang

3

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M Saitoh

4

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J G Mural

5

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D C Henley

6

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J Wimalasena

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language of work or name

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publication date

19 March 1999

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Journal of Biological Chemistry

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274

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12

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8208-16

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Microtubules and actin filaments: dynamic targets for cancer chemotherapy

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

p53-independent apoptosis induced by paclitaxel through an indirect mechanism

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Taxane-mediated gene induction is independent of microtubule stabilization: induction of transcription regulators and enzymes that modulate inflammation and apoptosis

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Inactivation of Bcl-2 by phosphorylation

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Taxol induces tyrosine phosphorylation of Shc and its association with Grb2 in murine RAW 264.7 cells

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Sounding the alarm: protein kinase cascades activated by stress and inflammation

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

AP-1 function and regulation

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Fas-ligand: privilege and peril

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Regulation of ceramide production and apoptosis

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Human epithelial ovarian cancer cell steroid secretion and its control by gonadotropins

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Three distinct signalling responses by murine fibroblasts to genotoxic stress

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Rho GTPases and the Actin Cytoskeleton

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx

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https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

ASK1 is essential for JNK/SAPK activation by TRAF2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Distinct roles for cyclin-dependent kinases in cell cycle control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

A role for JNK/SAPK in proliferation, but not apoptosis, of IL-3-dependent cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

The JUN kinase/stress-activated protein kinase pathway is required for epidermal growth factor stimulation of growth of human A549 lung carcinoma cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Activation of the JNK pathway is essential for transformation by the Met oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Caspases and caspase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Therapeutic intervention and signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

A Farnesyltransferase Inhibitor Induces Tumor Regression in Transgenic Mice Harboring Multiple Oncogenic Mutations by Mediating Alterations in Both Cell Cycle Control and Apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Commitment and effector phases of the physiological cell death pathway elucidated with respect to Bcl-2 caspase, and cyclin-dependent kinase activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Taxol-mediated augmentation of CD95 ligand-induced apoptosis of human malignant glioma cells: association with bcl-2 phosphorylation but neither activation of p53 nor G2/M cell cycle arrest

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Phosphorylation of Bcl-2 protein and association with p21Ras in Ras-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Angiotensin Type 2 Receptor Dephosphorylates Bcl-2 by Activating Mitogen-activated Protein Kinase Phosphatase-1 and Induces Apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Bcl-2 phosphorylation required for anti-apoptosis function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Ordering the cell death pathway. Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.12.8208

21 January 2018

Identifiers

10.1074/JBC.274.12.8208

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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