(Q28295415)

Protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform

GOA release 2020-03-11

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Journal of Biological Chemistry

GOA release 2020-03-11

1

W Hsu

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author name string

L Zeng

series ordinal

2

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F Costantini

series ordinal

3

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language of work or name

English

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publication date

5 February 1999

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published in

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volume

274

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issue

6

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page(s)

3439-45

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cites work

Basic processes underlying Agrobacterium-mediated DNA transfer to plant cells

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The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

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Lessons learned, promises kept: a biologist's eye view of the Genome Project

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GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits

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EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins

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Wnt signaling: a common theme in animal development

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RGS proteins and signaling by heterotrimeric G proteins

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Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis

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The dishevelled protein is modified by wingless signaling in Drosophila

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Signal transduction through beta-catenin and specification of cell fate during embryogenesis

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

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β-catenin is a target for the ubiquitin–proteasome pathway

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

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LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic.

21 January 2018

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Activation of Siamois by the Wnt pathway

21 January 2018

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

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Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin.

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

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Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription

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Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

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Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

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alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure

21 January 2018

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The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

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Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region

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A novel genetic system to detect protein-protein interactions

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The structure and regulation of protein phosphatases

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Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

21 January 2018

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Role of protein phosphatase 2A in Drosophila development.

21 January 2018

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Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila.

21 January 2018

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Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A.

21 January 2018

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The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.

21 January 2018

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Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Protein phosphatase 2A is a critical regulator of protein kinase C zeta signaling targeted by SV40 smallt to promote cell growth and NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Serine/threonine protein phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Regulation by tumour antigens defines a role for PP2A in signal transduction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Regulation of protein phosphatase 2A by direct interaction with casein kinase 2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Analysis of Dishevelled signalling pathways during Xenopus development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Genetic analysis of mutations at the fused locus in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Wnt-3a regulates somite and tailbud formation in the mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439

Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3439