(Q28264943)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

0 references

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

James J Foti

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Babho Devadoss

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Jonathan A Winkler

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

James J Collins

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

1 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

336

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

6079

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

315-319

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis

29 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

A common mechanism of cellular death induced by bactericidal antibiotics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles

20 March 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1219192

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1219192

Isolation of an E. coli Strain with a Mutation affecting DNA Polymerase

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1219192

Fix the antibiotics pipeline.

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Critical amino acids in human DNA polymerases eta and kappa involved in erroneous incorporation of oxidized nucleotides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

29 September 2017

Magic spot: (p) ppGpp

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

The nucleotide pool is a significant target for oxidative stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Mechanisms of formation, genotoxicity, and mutation of guanine oxidation products

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Clinical relevance of bacteriostatic versus bactericidal mechanisms of action in the treatment of Gram-positive bacterial infections

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Evolution of a molecular switch: universal bacterial GTPases regulate ribosome function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

The beta clamp targets DNA polymerase IV to DNA and strongly increases its processivity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Molecular mechanisms that confer antibacterial drug resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Protein oxidation in response to increased transcriptional or translational errors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Mutants of Escherichia coli with increased fidelity of DNA replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Lethal oxidative damage and mutagenesis are generated by iron in delta fur mutants of Escherichia coli: protective role of superoxide dismutase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Hydroxyl radical scavengers inhibit lymphocyte mitogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Radiation and hydrogen peroxide induced free radical damage to DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

The mutT defect does not elevate chromosomal fragmentation in Escherichia coli because of the surprisingly low levels of MutM/MutY-recognized DNA modifications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

Constraints on energy deposition and target size of multiply damaged sites associated with DNA double-strand breaks

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357493

A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates.

2 June 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1219192

Assessing the metabolic function of the MutT 8-oxodeoxyguanosine triphosphatase in Escherichia coli by nucleotide pool analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1219192

Dual hydrolysis of diphosphate and triphosphate derivatives of oxidized deoxyadenosine by Orf17 (NtpA), a MutT-type enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1219192

Effects of overexpression and antisense RNA expression of Orf17, a MutT-type enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1219192

Counteraction by MutT protein of transcriptional errors caused by oxidative damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1219192

Stoking the antibiotic pipeline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1219192

Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1219192

Enhancing the "A-rule" of translesion DNA synthesis: promutagenic DNA synthesis using modified nucleoside triphosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1219192

UmuD(2) inhibits a non-covalent step during DinB-mediated template slippage on homopolymeric nucleotide runs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1219192

Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1219192

A bacterial G protein-mediated response to replication arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1219192

The Influence of Oxygen on the Yield of DNA Double-Strand Breaks in X-Irradiated Escherichia coli K-12

21 January 2018

1 reference

12 December 2020

Hydrogen peroxide kills Staphylococcus aureus by reacting with staphylococcal iron to form hydroxyl radical

1 reference

12 December 2020

Potential of Escherichia coli GTP cyclohydrolase II for hydrolyzing 8-oxo-dGTP, a mutagenic substrate for DNA synthesis

1 reference

12 December 2020

Overproduction of Escherichia coli DNA polymerase DinB (Pol IV) inhibits replication fork progression and is lethal

1 reference

12 December 2020

Identifiers

DOI

10.1126/SCIENCE.1219192

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

22517853

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22517853%20AND%20SRC:MED&resulttype=core&format=json