(Q28205055)

7 January 2021

When is a lipid kinase not a lipid kinase? When it is a protein kinase

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7 January 2021

The genetic defect in ataxia-telangiectasia

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7 January 2021

The DNA-dependent protein kinase

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7 January 2021

Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling

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7 January 2021

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

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7 January 2021

Enhanced phosphorylation of p53 by ATM in response to DNA damage

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7 January 2021

Substrate specificities and identification of putative substrates of ATM kinase family members

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7 January 2021

Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase

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7 January 2021

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

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7 January 2021

Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.

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7 January 2021

Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity

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7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

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7 January 2021

Murine scid cells complement ataxia-telangiectasia cells and show a normal post-irradiation response of DNA synthesis

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7 January 2021

Intact G2-phase checkpoint in cells of a human cell line lacking DNA-dependent protein kinase activity.

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7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells.

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7 January 2021

Radiosensitivity in ataxia-telangiectasia: a new explanation

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7 January 2021

Radiosensitivity in ataxia-telangiectasia: anomalies in radiation-induced cell cycle delay

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7 January 2021

Utilization of oriented peptide libraries to identify substrate motifs selected by ATM.

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7 January 2021

p53 and ATM: cell cycle, cell death, and cancer.

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7 January 2021

The complexity of p53 modulation: emerging patterns from divergent signals

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

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7 January 2021

DNA damage induces phosphorylation of the amino terminus of p53

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7 January 2021

Regulation of p53 function and stability by phosphorylation

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7 January 2021

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

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7 January 2021

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

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7 January 2021

DNA damage activates p53 through a phosphorylation-acetylation cascade

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7 January 2021

Mdm2 promotes the rapid degradation of p53

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7 January 2021

Regulation of p53 stability by Mdm2

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7 January 2021

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

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7 January 2021

DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization

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7 January 2021

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

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7 January 2021

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

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7 January 2021

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

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7 January 2021

p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein

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7 January 2021

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

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7 January 2021

Radiation effects on DNA synthesis in a defined chromosomal replicon

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7 January 2021

Fragments of ATM which have dominant-negative or complementing activity

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7 January 2021

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

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7 January 2021

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

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7 January 2021

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

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7 January 2021

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

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7 January 2021

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

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7 January 2021

ATM-dependent phosphorylation of nibrin in response to radiation exposure

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7 January 2021

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

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7 January 2021

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

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7 January 2021

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

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7 January 2021

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

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7 January 2021

A checkpoint regulates the rate of progression through S phase in S. cerevisiae in Response to DNA damage

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7 January 2021

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

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7 January 2021

Cell cycle checkpoints: preventing an identity crisis

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7 January 2021

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

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7 January 2021

Radiation-induced G2 Delay and Spontaneous Chromosome Aberrations in Ataxia-telangiectasia Homozygotes and Heterozygotes

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7 January 2021

Mitotic and G 2 Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

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7 January 2021

Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems

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7 January 2021

Mitotic DNA damage and replication checkpoints in yeast

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7 January 2021

rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

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7 January 2021

Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms

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7 January 2021

Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways

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7 January 2021

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

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7 January 2021

Ataxia-telangiectasia: an inherited disorder of ionizing-radiation sensitivity in man. Progress in the elucidation of the underlying biochemical defect

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7 January 2021

On the nature of a defect in cells from individuals with ataxia-telangiectasia

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7 January 2021

Histone H1 dephosphorylation is mediated through a radiation-induced signal transduction pathway dependent on ATM.

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7 January 2021

Sensing of ionizing radiation-induced DNA damage by ATM through interaction with histone deacetylase

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7 January 2021

DNA double strand break repair in mammalian cells

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7 January 2021

High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia

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7 January 2021

High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines

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7 January 2021

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

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7 January 2021

The controlling role of ATM in homologous recombinational repair of DNA damage

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7 January 2021

Association of BRCA1 with Rad51 in mitotic and meiotic cells

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7 January 2021

BRCA1 required for transcription-coupled repair of oxidative DNA damage

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7 January 2021

Brca1 controls homology-directed DNA repair

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7 January 2021

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

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7 January 2021

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

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7 January 2021

Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm

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7 January 2021

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

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7 January 2021

A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-kappaB.

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7 January 2021

ATM binds to beta-adaptin in cytoplasmic vesicles

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7 January 2021

Expression of the ataxia-telangiectasia gene (ATM) product in human cerebellar neurons during development

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7 January 2021

ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation.

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7 January 2021

Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1.

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7 January 2021

Accessing DNA damage in chromatin: insights from transcription

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7 January 2021

A role for ATR in the DNA damage-induced phosphorylation of p53

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7 January 2021

TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1

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7 January 2021

The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene

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7 January 2021

cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein

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7 January 2021

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

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7 January 2021

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

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7 January 2021

Identifiers

DOI

10.1038/35043058

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1037972283

0 references

Fatcat ID

release_qx4cukni7zf2rfwaynjl6lxjne

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qx4cukni7zf2rfwaynjl6lxjne

24 November 2022

mapped directly with Wikidata item

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

11252893

1 reference

Consolidated OpenCitations Corpus – April 2017