(Q28189437)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12682053%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling (English)

1 reference

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2 November 2019

2

1 reference

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2 November 2019

Richard A. Anderson

series ordinal

5

1 reference

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2 November 2019

1

Renee L Doughman

1 reference

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2 November 2019

4

Matthew W Bunce

1 reference

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2 November 2019

author name string

Michelle L Wojtasiak

series ordinal

3

1 reference

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2 November 2019

language of work or name

English

0 references

publication date

6 April 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12682053%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

2 November 2019

published in

1 reference

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2 November 2019

volume

278

1 reference

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2 November 2019

issue

25

1 reference

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2 November 2019

page(s)

23036-23045

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12682053%20AND%20SRC:MED&resulttype=core&format=json

Cell migration: a physically integrated molecular process

2 November 2019

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Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate

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Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex

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Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

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Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes.

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PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

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Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family

21 January 2018

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Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3.

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Inhibition of phosphatidylinositol-4-phosphate 5-kinase Ialpha impairs localized actin remodeling and suppresses phagocytosis.

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Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

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Rho GTPases and the Actin Cytoskeleton

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

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Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

21 January 2018

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Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by the Rac and extracellular signal-regulated kinase pathways.

21 January 2018

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Rho Family GTPases Bind to Phosphoinositide Kinases

21 January 2018

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Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol 4-phosphate 5-kinase in Swiss 3T3 cells.

21 January 2018

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The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

21 January 2018

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Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation

21 January 2018

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G-protein-coupled receptor activation induces the membrane translocation and activation of phosphatidylinositol-4-phosphate 5-kinase I alpha by a Rac- and Rho-dependent pathway

21 January 2018

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Type II phosphatidylinositol 4-kinase beta is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP.

21 January 2018

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Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules

21 January 2018

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Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors

21 January 2018

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The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells.

21 January 2018

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

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Dynamics of phosphatidylinositol 4,5-bisphosphate in actin-rich structures

21 January 2018

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PIP kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapse

21 January 2018

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Involvement of Phosphatidylinositide 3′-Kinase and Rac in Platelet-Derived Growth Factor-Induced Actin Reorganization and Chemotaxis

21 January 2018

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Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1.

21 January 2018

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Agonist-induced PIP(2) hydrolysis inhibits cortical actin dynamics: regulation at a global but not at a micrometer scale

21 January 2018

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Lipid products of phosphoinositide 3-kinase interact with Rac1 GTPase and stimulate GDP dissociation

21 January 2018

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Cytoskeletal reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase gamma, a Rac guanosine exchange factor, and Rac.

21 January 2018

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SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling

21 January 2018

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Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

21 January 2018

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Inhibition of MG-63 cell proliferation and PDGF-stimulated cellular processes by inhibitors of phosphatidylinositol 3-kinase

21 January 2018

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SH2-Bbeta is a Rac-binding protein that regulates cell motility

21 January 2018

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Characterization of a Rac1- and RhoGDI-Associated Lipid Kinase Signaling Complex

21 January 2018

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The synthesis and cellular roles of phosphatidylinositol 4,5-bisphosphate

21 January 2018

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The yeast synaptojanin-like proteins control the cellular distribution of phosphatidylinositol (4,5)-bisphosphate

21 January 2018

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MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae.

21 January 2018

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Phosphatidylinositol-4-phosphate 5-kinase localized on the plasma membrane is essential for yeast cell morphogenesis

21 January 2018

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Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis

21 January 2018

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Localized Rac activation dynamics visualized in living cells

21 January 2018

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Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly

21 January 2018

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21 January 2018

Actin-binding proteins

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Actin activates a cryptic dimerization potential of the vinculin tail domain

21 January 2018

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Massive actin polymerization induced by phosphatidylinositol-4-phosphate 5-kinase in vivo

21 January 2018

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The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity

21 January 2018

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Stereo-specific substrate recognition by phosphatidylinositol phosphate kinases is swapped by changing a single amino acid residue

21 January 2018

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Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells

21 January 2018

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Intracellular signalling. PI 3-kinase puts GTP on the Rac

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M211397200

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12682053%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017