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Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compounds
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title
Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compounds
(English)
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author name string
Ningning Liu
series ordinal
1
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stated in
Crossref
Hongbiao Huang
series ordinal
2
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stated in
Crossref
Q. Ping Dou
series ordinal
3
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Crossref
Jinbao Liu
series ordinal
4
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stated in
Crossref
language of work or name
English
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PubMed
publication date
31 May 2015
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published in
Oncoscience
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volume
2
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PubMed
issue
5
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PubMed
page(s)
457-66
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PubMed
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A cryptic protease couples deubiquitination and degradation by the proteasome
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Breaking the chains: structure and function of the deubiquitinases
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A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14
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Antiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein response
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A novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents
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Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth
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A novel proteasome inhibitor suppresses tumor growth via targeting both 19S proteasome deubiquitinases and 20S proteolytic peptidases
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The 19S Deubiquitinase inhibitor b-AP15 is enriched in cells and elicits rapid commitment to cell death.
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Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia
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Gold(III)-dithiocarbamato peptidomimetics in the forefront of the targeted anticancer therapy: preclinical studies against human breast neoplasia.
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Gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl downregulation
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Proapoptotic effects of the novel proteasome inhibitor b-AP15 on multiple myeloma cells and natural killer cells
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USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis
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Deubiquitinase inhibition of 19S regulatory particles by 4-arylidene curcumin analog AC17 causes NF-κB inhibition and p53 reactivation in human lung cancer cells.
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29 September 2017
Overexpression of USP14 protease reduces I-κB protein levels and increases cytokine release in lung epithelial cells
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29 September 2017
Ubiquitin C-terminal hydrolase-L5 is required for high glucose-induced transforming growth factor-β receptor I expression and hypertrophy in mesangial cells
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29 September 2017
Structural biology of the proteasome
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Ubiquitin C-terminal Hydrolase 37, a novel predictor for hepatocellular carcinoma recurrence, promotes cell migration and invasion via interacting and deubiquitinating PRP19.
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Usp14 deficiency increases tau phosphorylation without altering tau degradation or causing tau-dependent deficits
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29 September 2017
1,10-Phenanthroline promotes copper complexes into tumor cells and induces apoptosis by inhibiting the proteasome activity.
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29 September 2017
A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance
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29 September 2017
Dithiocarbamate-based coordination compounds as potent proteasome inhibitors in human cancer cells
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29 September 2017
The small molecule inhibitor PR-619 of deubiquitinating enzymes affects the microtubule network and causes protein aggregate formation in neural cells: implications for neurodegenerative diseases
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29 September 2017
A small-molecule inhibitor of deubiquitinating enzyme USP14 inhibits Dengue virus replication
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Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes
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29 September 2017
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29 September 2017
A novel copper complex induces paraptosis in colon cancer cells via the activation of ER stress signalling
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29 September 2017
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29 September 2017
Trimming of Ubiquitin Chains by Proteasome-associated Deubiquitinating Enzymes
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29 September 2017
The tumor proteasome as a novel target for gold(III) complexes: implications for breast cancer therapy
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29 September 2017
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival
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29 September 2017
Copper-triggered aggregation of ubiquitin
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29 September 2017
A mutation linked to retinitis pigmentosa in HPRP31 causes protein instability and impairs its interactions with spliceosomal snRNPs.
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29 September 2017
Shikonin exerts antitumor activity via proteasome inhibition and cell death induction in vitro and in vivo.
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29 September 2017
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29 September 2017
Gold complexes as prospective metal-based anticancer drugs
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29 September 2017
Inhibition of the proteasome activity by gallium(III) complexes contributes to their anti prostate tumor effects
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29 September 2017
Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts
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29 September 2017
Antiproliferative and apoptotic effects of two new gold(III) methylsarcosinedithiocarbamate derivatives on human acute myeloid leukemia cells in vitro.
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29 September 2017
A novel anticancer gold(III) dithiocarbamate compound inhibits the activity of a purified 20S proteasome and 26S proteasome in human breast cancer cell cultures and xenografts.
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29 September 2017
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29 September 2017
Non-apoptotic programmed cell death induced by a copper(II) complex in human fibrosarcoma cells.
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29 September 2017
Copper in medicine: homeostasis, chelation therapy and antitumor drug design
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29 September 2017
Gold(III) dithiocarbamate derivatives for the treatment of cancer: solution chemistry, DNA binding, and hemolytic properties
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29 September 2017
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29 September 2017
UCH-L1 aggresome formation in response to proteasome impairment indicates a role in inclusion formation in Parkinson's disease
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29 September 2017
Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells
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29 September 2017
The essential 26S proteasome subunit Rpn11 confers multidrug resistance to mammalian cells
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29 September 2017
Ubiquitin-aldehyde: a general inhibitor of ubiquitin-recycling processes
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29 September 2017
MiR-4782-3p inhibited non-small cell lung cancer growth via USP14.
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27 November 2018
Gambogic acid is a tissue-specific proteasome inhibitor in vitro and in vivo
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27 November 2018
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27 November 2018
Cu(II) binding to monomeric, oligomeric, and fibrillar forms of the Alzheimer's disease amyloid-beta peptide.
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27 November 2018
New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications
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27 November 2018
Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity
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27 November 2018
Gold dithiocarbamate derivatives as potential antineoplastic agents: design, spectroscopic properties, and in vitro antitumor activity.
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27 November 2018
Effects of zinc pyrithione and copper pyrithione on microbial community function and structure in sediments.
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27 November 2018
Sanggenon C decreases tumor cell viability associated with proteasome inhibition
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.18632/ONCOSCIENCE.167
0 references
PMC publication ID
4468331
1 reference
stated in
PubMed
PubMed publication ID
26097878
1 reference
stated in
PubMed
ResearchGate publication ID
280032444
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