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New Mechanisms of Tumor-Associated Macrophages on Promoting Tumor Progression: Recent Research Advances and Potential Targets for Tumor Immunotherapy

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8 February 2021

New Mechanisms of Tumor-Associated Macrophages on Promoting Tumor Progression: Recent Research Advances and Potential Targets for Tumor Immunotherapy (English)

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18 October 2019

cancer immunotherapy

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based on heuristic

inferred from abstract

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8 February 2021

tumor progression

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based on heuristic

inferred from title

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7 June 2020

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Shulin He

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Wei Hou

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2016

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16 November 2016

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3 April 2019

12 October 2019

18 October 2019

8 February 2021

Journal of Immunology Research

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12 October 2019

18 October 2019

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2016

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9720912

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Tumor-Associated Macrophages and Neutrophils in Tumor Microenvironment

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Effect and Molecular Mechanisms of Traditional Chinese Medicine on Regulating Tumor Immunosuppressive Microenvironment

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CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages

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Functional Relationship between Tumor-Associated Macrophages and Macrophage Colony-Stimulating Factor as Contributors to Cancer Progression

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Immunity, Inflammation, and Cancer

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Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis

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Angiopoietins in angiogenesis

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20 March 2017

Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

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7 April 2017

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

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CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

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Macrophage biology in development, homeostasis and disease

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Smoldering and polarized inflammation in the initiation and promotion of malignant disease

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Ontogeny of Tumor-associated Macrophages and Its Implication in Cancer Regulation

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CD163(+) M2-type tumor-associated macrophage support the suppression of tumor-infiltrating T cells in osteosarcoma

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Effect of tumor-associated macrophages on gastric cancer stem cell in omental milky spots and lymph node micrometastasis

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Inhibition of tumor growth and metastasis by photoimmunotherapy targeting tumor-associated macrophage in a sorafenib-resistant tumor model

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A Breakthrough: Macrophage-Directed Cancer Immunotherapy.

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Luteolin inhibits recruitment of monocytes and migration of Lewis lung carcinoma cells by suppressing chemokine (C-C motif) ligand 2 expression in tumor-associated macrophage

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Cannabinoid receptor-2 agonist inhibits macrophage induced EMT in non-small cell lung cancer by downregulation of EGFR pathway.

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Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities

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M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment.

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CCL18 from tumor-associated macrophages promotes angiogenesis in breast cancer

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Dequalinium blocks macrophage-induced metastasis following local radiation

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Ovarian cancer stem cells induce the M2 polarization of macrophages through the PPARγ and NF-κB pathways

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Prognostic value of tumor-associated macrophages according to histologic locations and hormone receptor status in breast cancer

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Lymphatic function and immune regulation in health and disease

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The irradiated tumor microenvironment: role of tumor-associated macrophages in vascular recovery

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29 September 2017

M2-polarized tumor-associated macrophages promoted epithelial-mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway

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29 September 2017

Macrophage regulation of tumor responses to anticancer therapies

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29 September 2017

The metastasis-promoting roles of tumor-associated immune cells

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29 September 2017

CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy in prostate cancer

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HIFs, angiogenesis, and cancer

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29 September 2017

Impact of stem cell marker expression on recurrence of TACE-treated hepatocellular carcinoma post liver transplantation

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29 September 2017

Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Lymphatic microvessel density and vascular endothelial growth factor-C and -D as prognostic factors in breast cancer: a systematic review and meta-analysis of the literature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Irradiation promotes an m2 macrophage phenotype in tumor hypoxia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

The influence of macrophages and the tumor microenvironment on natural killer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Aptamer-mediated blockade of IL4Rα triggers apoptosis of MDSCs and limits tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Cancer-related inflammation: common themes and therapeutic opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Lymphatic microvessel density as a prognostic factor in non-small cell lung carcinoma: a meta-analysis of the literature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

M2-Polarized tumor-associated macrophages are associated with poor prognoses resulting from accelerated lymphangiogenesis in lung adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Interferon-gamma and tumor necrosis factor-alpha induce an immunoinhibitory molecule, B7-H1, via nuclear factor-kappaB activation in blasts in myelodysplastic syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Nitric oxide permits hypoxia-induced lymphatic perfusion by controlling arterial-lymphatic conduits in zebrafish and glass catfish.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: contrasting, overlapping and compensatory functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

COX-2, VEGF and tumour angiogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Tumor microenvironment of metastasis in human breast carcinoma: a potential prognostic marker linked to hematogenous dissemination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Colony-stimulating factor-1 in immunity and inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

29 September 2017

Alternatively activated macrophages are associated with metastasis and poor prognosis in prostate adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

2 June 2018

Osteopontin-expressing macrophages in non-small cell lung cancer predict survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

2 June 2018

Role of cancer stem cell-associated inflammation in creating pro-inflammatory tumorigenic microenvironments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

2 June 2018

Macrophages increase the resistance of pancreatic adenocarcinoma cells to gemcitabine by upregulating cytidine deaminase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

2 June 2018

Trabectedin: A drug from the sea that strikes tumor-associated macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

2 June 2018

Macrophages: Good guys in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

2 June 2018

Myeloid cells in tumor inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

2 June 2018

Angiogenesis and Tumor Metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5128713

2 June 2018

High infiltration of tumor-associated macrophages is associated with a poor response to chemotherapy and poor prognosis of patients undergoing neoadjuvant chemotherapy for esophageal cancer.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Interstitial tumor-associated macrophages combined with tumor-derived colony-stimulating factor-1 and interleukin-6, a novel prognostic biomarker in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Tumor-associated macrophages are correlated with tamoxifen resistance in the postmenopausal breast cancer patients.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Microlocalization of CD68+ tumor-associated macrophages in tumor stroma correlated with poor clinical outcomes in oral squamous cell carcinoma patients.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Expression of tumor-associated macrophage in progression of human glioma

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Expression of M2-polarized macrophages is associated with poor prognosis for advanced epithelial ovarian cancer

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Tumor-Associated Macrophages Associate with Cerebrospinal Fluid Interleukin-10 and Survival in Primary Central Nervous System Lymphoma (PCNSL).

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Expression of tumor-associated macrophages and vascular endothelial growth factor correlates with poor prognosis of peripheral T-cell lymphoma, not otherwise specified

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Pattern of use of radiotherapy for lung cancer: a descriptive study.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Impeding macrophage entry into hypoxic tumor areas by Sema3A/Nrp1 signaling blockade inhibits angiogenesis and restores antitumor immunity.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Lymphatics: where the circulation meets the immune system

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Significance of Vascular Endothelial Growth Factor (VEGF)-C and VEGF-D in the Progression of Cutaneous Melanoma.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Circulating stem cell-like epithelial cell adhesion molecule-positive tumor cells indicate poor prognosis of hepatocellular carcinoma after curative resection

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

Infiltration of CD40-positive tumor-associated macrophages indicates a favorable prognosis in colorectal cancer patients

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F9720912

21 January 2018

M2-polarized tumor-associated macrophage infiltration of regional lymph nodes is associated with nodal lymphangiogenesis and occult nodal involvement in pN0 pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27975071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of CD163, interleukin-10, and interferon-gamma in oral squamous cell carcinoma: mutual relationships and prognostic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/27975071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High expression of tumor-infiltrating macrophages correlates with poor prognosis in patients with diffuse large B-cell lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27975071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-associated macrophages, epidermal growth factor receptor correlated with the triple negative phenotype in endometrial endometrioid adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27975071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VEGF-C expressing tumor-associated macrophages in lymph node positive breast cancer: impact on lymphangiogenesis and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/27975071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of AEG-1 and microvessel density correlates with metastasis and prognosis of oral squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27975071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage content of murine sarcomas and carcinomas: associations with tumor growth parameters and tumor radiocurability

1 reference

https://pubmed.ncbi.nlm.nih.gov/27975071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased infiltration of tumor associated macrophages is associated with poor prognosis of bladder carcinoma in situ after intravesical bacillus Calmette-Guerin instillation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27975071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-associated macrophages correlate with response to epidermal growth factor receptor-tyrosine kinase inhibitors in advanced non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27975071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-associated macrophages and the profile of inflammatory cytokines in oral squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27975071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2016/9720912

2 references

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27975071%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PMC publication ID

2 references

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27975071%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

2 references

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27975071%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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