(Q27552248)

Mitochondrial import inner membrane translocase subunit Tim50

1 reference

HAD superfamily

1 reference

Mitochondrial protein translocase

1 reference

Transporter Classification Database ID

3.A.8.1.1

hierarchical database ID heuristic

2 October 2019

based on heuristic

FCP1 homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

phosphoprotein phosphatase activity

IBA

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

IBA

protein binding

7 references

9 May 2019

NMR analyses on the interactions of the yeast Tim50 C-terminal region with the presequence and Tim50 core domain.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

9 May 2019

Lateral release of proteins from the TOM complex into the outer membrane of mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

9 May 2019

Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

9 May 2019

Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

9 May 2019

Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

9 May 2019

Signal recognition initiates reorganization of the presequence translocase during protein import

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

9 May 2019

Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

identical protein binding

protein transmembrane transporter activity

1 reference

9 May 2019

Tim50 maintains the permeability barrier of the mitochondrial inner membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

cell component

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

1 reference

9 May 2019

TIM23 mitochondrial import inner membrane translocase complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02776&geneProductId=UniProtKB:Q02776

3 references

27 February 2018

27 February 2018

The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02776&geneProductId=UniProtKB:Q02776

27 February 2018

Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02776&geneProductId=UniProtKB:Q02776

integral component of membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

1 reference

9 May 2019

mitochondrion

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02776&geneProductId=UniProtKB:Q02776

1 reference

10 September 2018

mitochondrial inner membrane

TIM23 mitochondrial import inner membrane translocase complex

TAS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

4 references

9 May 2019

9 May 2019

Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

9 May 2019

The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

IBA

mitochondrion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

3 references

9 May 2019

9 May 2019

Quantitative variations of the mitochondrial proteome and phosphoproteome during fermentative and respiratory growth in Saccharomyces cerevisiae.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

HDA

9 May 2019

Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

protein import into mitochondrial matrix

HDA

biological process

2 references

27 February 2018

The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02776&geneProductId=UniProtKB:Q02776

27 February 2018

Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02776&geneProductId=UniProtKB:Q02776

regulation of mitochondrial membrane permeability

1 reference

9 May 2019

Tim50 maintains the permeability barrier of the mitochondrial inner membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

protein dephosphorylation

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

protein import into mitochondrial matrix

Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

9 May 2019

The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02776

1 reference

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Transporter Classification Database ID

1 reference

20 March 2022

3.A.8.1.1

2 references

Transporter Classification database

13 March 2020

Transporter Classification database