(Q27551203)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P15731

Ubiquitin-conjugating enzyme E2 family

1 reference

based on heuristic

inferred from protein domain or family

Ubiquitin-conjugating enzyme, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

1 reference

14 February 2019

IEA

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

1 reference

14 February 2019

protein-macromolecule adaptor activity

IEA

1 reference

14 February 2019

A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

ubiquitin binding

The essential Ubc4/Ubc5 function in yeast is HECT E3-dependent, and RING E3-dependent pathways require only monoubiquitin transfer by Ubc4.

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

14 February 2019

The essential Ubc4/Ubc5 function in yeast is HECT E3-dependent, and RING E3-dependent pathways require only monoubiquitin transfer by Ubc4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

1 reference

14 February 2019

ubiquitin-protein transferase activity

IEA

protein binding

1 reference

14 February 2019

The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

ubiquitin protein ligase binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

ubiquitin conjugating enzyme activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

proteasome binding

1 reference

14 February 2019

Evidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

cell component

proteasome complex

1 reference

5 June 2018

Evidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasome

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15731&geneProductId=UniProtKB:P15731

ubiquitin ligase complex

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

nucleus

1 reference

14 February 2019

Ubiquitylation regulates interactions of astral microtubules with the cleavage apparatus.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

cytoplasm

1 reference

14 February 2019

Ubiquitylation regulates interactions of astral microtubules with the cleavage apparatus.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

cytoplasm protein quality control by the ubiquitin-proteasome system

biological process

1 reference

14 February 2019

Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

1 reference

14 February 2019

A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

protein monoubiquitination

1 reference

14 February 2019

Selective ubiquitination of calmodulin by UBC4 and a putative ubiquitin protein ligase (E3) from Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

cellular response to heat

1 reference

14 February 2019

Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

protein polyubiquitination

A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

14 February 2019

Distinct ubiquitination cascades act on the peroxisomal targeting signal type 2 co-receptor Pex18p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

14 February 2019

Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

ubiquitin-dependent protein catabolic process

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15731

Ubiquitin-conjugating enzyme, active site

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P15731

Ubiquitin-conjugating enzyme E2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P15731

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference