(Q24323265)

1

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H Yu

2

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S H Liu

3

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F M Brodsky

4

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B M Peterlin

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

5

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language of work or name

English

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publication date

May 1998

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published in

Immunity

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volume

8

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issue

5

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page(s)

647-56

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Adaptor self-aggregation, adaptor-receptor recognition and binding of alpha-adaptin subunits to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin-coated pits

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Physical and functional interaction of Nef with Lck. HIV-1 Nef-induced T-cell signaling defects.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

The role of Nef in the replication cycle of the human and simian immunodeficiency viruses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Identification of a nef allele that causes lymphocyte activation and acute disease in Macaque monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Human immunodeficiency virus type 1 envelope protein endocytosis mediated by a highly conserved intrinsic internalization signal in the cytoplasmic domain of gp41 is suppressed in the presence of the Pr55gag precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Nef-mediated Clathrin-coated Pit Formation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Roles for a cytoplasmic tyrosine and tyrosine kinase activity in the interactions of Neu receptors with coated pits

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Bovine papillomavirus E5 oncoprotein binds to the 16K component of vacuolar H(+)-ATPases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Myristoylation-dependent binding of HIV-1 Nef to CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Linking cargo to vesicle formation: receptor tail interactions with coat proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Cell surface CD4 downregulation and resistance to superinfection induced by a defective provirus of HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

A Dominant-negative Clathrin Mutant Differentially Affects Trafficking of Molecules with Distinct Sorting Motifs in the Class II Major Histocompatibility Complex (MHC) Pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Legitimate and illegitimate cleavage of human immunodeficiency virus glycoproteins by furin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Interaction of Endocytic Signals from the HIV-1 Envelope Glycoprotein Complex with Members of the Adaptor Medium Chain Family

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Immunopathogenesis of HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Evidence for rapid disappearance of initially expanded HIV-specific CD8+ T cell clones during primary HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Molecular biology and function of CD4 and CD8

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

The 50 kDa protein subunit of assembly polypeptide (AP) AP-2 adaptor from clathrin-coated vesicles is phosphorylated on threonine-156 by AP-1 and a soluble AP50 kinase which co-purifies with the assembly polypeptides

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

CD4: collaborator in immune recognition and HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Nef-CD4 physical interaction sensed with the yeast two-hybrid system

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Nef proteins encoded by human and simian immunodeficiency viruses induce the accumulation of endosomes and lysosomes in human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Reduced cell surface expression of processed human immunodeficiency virus type 1 envelope glycoprotein in the presence of Nef.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-Iiodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Structure, function and regulation of the vacuolar (H+)-ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

HIV accessory proteins: leading roles for the supporting cast.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

In vivo phosphorylation of adaptors regulates their interaction with clathrin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021

Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980569-5

7 January 2021