(Q24296490)

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Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy

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Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy (English)

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Ig kappa chain V-III region B6

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GOA release 2020-03-11

immune response

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GOA release 2020-03-11

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based on heuristic

inferred from title

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based on heuristic

inferred from title

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based on heuristic

inferred from title

chronic lymphocytic leukemia

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based on heuristic

inferred from title

author name string

T J Kipps

1

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E Tomhave

2

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P P Chen

3

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D A Carson

4

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language of work or name

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publication date

1 March 1988

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Journal of Experimental Medicine

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167

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3

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840-52

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Human immunoglobulin variable region genes--DNA sequences of two V kappa genes and a pseudogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

19 March 2017

Immunoglobulin genes of different subgroups are interdigitated within the VK locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

19 March 2017

Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

19 March 2017

DNA sequencing with chain-terminating inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

19 March 2017

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

19 March 2017

57 Sequencing end-labeled DNA with base-specific chemical cleavages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

19 March 2017

Human immunoglobulin kappa light chain genes of subgroups II and III

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

19 March 2017

Amino acid sequence of the variable regions of light chains from two idiotypically cross-reactive human IgM anti-gamma-globulins of the Wa group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

19 March 2017

Evolution of immunoglobulin V genes: evidence indicating that recently duplicated human V kappa sequences have diverged by gene conversion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

19 March 2017

Evolution of human immunoglobulin kappa J region genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

19 March 2017

Human B cell development. II. Subpopulations in the human fetus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

19 March 2017

Amino acid sequence of a light chain variable region of a human rheumatoid factor of the Wa idiotypic group, in part predicted by its reactivity with antipeptide antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

19 March 2017

Ribonucleic acid isolated by cesium chloride centrifugation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

7 April 2017

Dideoxy sequencing method using denatured plasmid templates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

7 April 2017

Genetic factors predisposing to chronic lymphocytic leukemia and to autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

An antigen shared by a human T cell subset and B cell chronic lymphocytic leukemic cells. Distribution on normal and malignant lymphoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

An idiotype-specific helper population that bears immunoglobulin, Ia, and Lyt-1 determinants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

Complete amino acid sequence of variable domains from two monoclonal human anti-gamma globulins of the Wa cross-idiotypic group: suggestion that the J segments are involved in the structural correlate of the idiotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

Composite human VKgenes and a model of their evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

Polyadenylic Acid Sequences in the Heterogeneous Nuclear RNA and Rapidly-Labeled Polyribosomal RNA of HeLa Cells: Possible Evidence for a Precursor Relationship

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

Light chain sequences of human IgM cold agglutinins (variable-region subgroups amino-acid sequence-kappa light chain-N-terminal).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

Anti-human immunoglobulin G activity of membrane-bound monoclonal immunoglobulin M in lymphoproliferative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

Idiotype variant cell populations in patients with B cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

Somatic mutation in human B-cell tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

Isolation and characterization of human VkIII germ-line genes. Implications for the molecular basis of human VkIII light chain diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

High-frequency expression of a conserved kappa light-chain variable-region gene in chronic lymphocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

Human rheumatoid factor crossidiotypes. II. Primary structure-dependent crossreactive idiotype, PSL2-CRI, present on Wa monoclonal rheumatoid factors is present on Bla and other IgM kappa monoclonal autoantibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

The human V kappa locus. Characterization of extended immunoglobulin gene regions by cosmid cloning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

A conserved human germline V kappa gene directly encodes rheumatoid factor light chains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

Complete amino acid sequences of variable regions of two human IgM rheumatoid factors, BOR and KAS of the Wa idiotypic family, reveal restricted use of heavy and light chain variable and joining region gene segments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

Complete sequence of constant and 3′ noncoding regions of an immunoglobulin mRNA using the dideoxynucleotide method of RNA sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

27 September 2017

Human T cell antigens defined by monoclonal antibodies: the 65,000-dalton antigen of T cells (T65) is also found on chronic lymphocytic leukemia cells bearing surface immunoglobulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

30 May 2018

Organization and evolution of a gene cluster for human immunoglobulin variable regions of the kappa type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

30 May 2018

Clustering of extensive somatic mutations in the variable region of an immunoglobulin heavy chain gene from a human B cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

30 May 2018

HTLV-I--associated B-cell CLL: indirect role for retrovirus in leukemogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

30 May 2018

Human V kappa immunoglobulin gene number: implications for the origin of antibody diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

29 November 2018

Cross idiotypic specificity among cold agglutinins in relation to combining activity for blood group-related antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

29 November 2018

Sequence similarities and cross-idiotypic specificity of L chains among human monoclonal IgM kappa with anti-gamma-globulin activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2188892

29 November 2018

Structural similarities in the kappa light chains of human rheumatoid factor paraproteins and serum immunoglobulins bearing a cross-reactive idiotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on B lymphoid tumors treated with monoclonal anti-idiotype antibodies: correlation with clinical responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A large section of the gene locus encoding human immunoglobulin variable regions of the kappa type is duplicated

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fetal and neonatal development of human spleen: an immunohistological study

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic influence on the levels of circulating CD5 B lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new human T-cell differentiation antigen: Unexpected expression on chronic lymphocytic leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preferential association of kappa IIIb light chains with monoclonal human IgM kappa autoantibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common idiotope on human rheumatoid factors identified by a hybridoma antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The VKIIIb light chain sub-subgroup: restricted association with mu heavy chain in normal human serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous alteration of idiotype in a monoclonal B-cell lymphoma. Escape from detection by anti-idiotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.167.3.840

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