Wikidata

(Q22675731)

English

KLRC4-KLRK1 readthrough

mammalian protein found in Homo sapiens

  • NKG2-D type II integral membrane protein
  • killer cell lectin-like receptor subfamily K member 1
  • NK cell receptor D
  • KLRC4-KLRK1
  • killer cell lectin-like receptor subfamily K, member 1
  • NKG2-D-activating NK receptor
  • KLRK1
  • NK Cell Lectin-Like Receptor Subfamily K
In more languages
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No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
13 references
retrieved
9 May 2019
stated in
An activating immunoreceptor complex formed by NKG2D and DAP10
GOA
curator
UniProt
UniProt protein ID
P26718
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
9 May 2019
stated in
CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling
GOA
curator
UniProt
UniProt protein ID
P26718
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
9 May 2019
stated in
Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
GOA
curator
UniProt
UniProt protein ID
P26718
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
9 May 2019
stated in
The NKG2D ligand ULBP4 binds to TCRgamma9/delta2 and induces cytotoxicity to tumor cells through both TCRgammadelta and NKG2D.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
9 May 2019
stated in
Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
9 May 2019
stated in
Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
9 May 2019
stated in
Four novel ULBP splice variants are ligands for human NKG2D.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
9 May 2019
stated in
A novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycans
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
9 May 2019
stated in
ULBP6/RAET1L is an additional human NKG2D ligand
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
9 May 2019
stated in
A disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand binding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
9 May 2019
stated in
Differential NKG2D binding to highly related human NKG2D ligands ULBP2 and RAET1G is determined by a single amino acid in the alpha2 domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
9 May 2019
stated in
Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
9 May 2019
stated in
Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
protein binding
determination method or standard
IBA
IPI
14 references
retrieved
1 January 2018
stated in
Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
GOA
curator
UniProt
UniProt protein ID
P26718
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
An activating immunoreceptor complex formed by NKG2D and DAP10
GOA
curator
UniProt
UniProt protein ID
P26718
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling
GOA
curator
UniProt
UniProt protein ID
P26718
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
A novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycans
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
ULBP6/RAET1L is an additional human NKG2D ligand
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
Four novel ULBP splice variants are ligands for human NKG2D.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
Differential NKG2D binding to highly related human NKG2D ligands ULBP2 and RAET1G is determined by a single amino acid in the alpha2 domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
The NKG2D ligand ULBP4 binds to TCRgamma9/delta2 and induces cytotoxicity to tumor cells through both TCRgammadelta and NKG2D.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
A disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand binding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IPI
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26718
determination method or standard
IBA
cell component
biological process

Identifiers

MeSH descriptor ID
D055655
subject named as
NK Cell Lectin-Like Receptor Subfamily K
0 references
 
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