(Q21983985)

Winged helix-like DNA-binding domain superfamily

1 reference

Fork head domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Fork head domain conserved site1, protein family

1 reference

based on heuristic

inferred from protein domain or family

Fork head domain conserved site 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

sequence-specific DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

1 reference

9 May 2019

DNA-binding transcription factor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

1 reference

9 May 2019

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61080&geneProductId=UniProtKB:Q61080

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61080&geneProductId=UniProtKB:Q61080

biological process

somitogenesis

1 reference

9 May 2019

The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

1 reference

9 May 2019

lung morphogenesis

1 reference

9 May 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

embryonic foregut morphogenesis

1 reference

9 May 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

lung development

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

Defects in pulmonary vasculature and perinatal lung hemorrhage in mice heterozygous null for the Forkhead Box f1 transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

positive regulation of cell migration

1 reference

9 May 2019

Forkhead box F1 is essential for migration of mesenchymal cells and directly induces integrin-beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

cellular response to organic cyclic compound

1 reference

9 May 2019

Pulmonary mastocytosis and enhanced lung inflammation in mice heterozygous null for the Foxf1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

extracellular matrix organization

1 reference

9 May 2019

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

in utero embryonic development

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

negative regulation of transcription by RNA polymerase II

negative regulation of mast cell degranulation

1 reference

9 May 2019

Pulmonary mastocytosis and enhanced lung inflammation in mice heterozygous null for the Foxf1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

smooth muscle cell differentiation

1 reference

14 February 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61080&geneProductId=UniProtKB:Q61080

1 reference

27 March 2018

right lung morphogenesis

1 reference

9 May 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

cellular response to cytokine stimulus

1 reference

9 May 2019

The winged helix transcriptional activator HFH-8 is expressed in the mesoderm of the primitive streak stage of mouse embryos and its cellular derivatives

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

vasculogenesis

3 references

9 May 2019

The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

Hedgehog induction of murine vasculogenesis is mediated by Foxf1 and Bmp4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

Defects in pulmonary vasculature and perinatal lung hemorrhage in mice heterozygous null for the Forkhead Box f1 transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

determination of left/right symmetry

1 reference

9 May 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

establishment of epithelial cell apical/basal polarity

1 reference

9 May 2019

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

positive regulation of mesenchymal cell proliferation

1 reference

9 May 2019

The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

animal organ morphogenesis

1 reference

9 May 2019

Haploinsufficiency of the mouse Forkhead Box f1 gene causes defects in gall bladder development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

detection of wounding

1 reference

9 May 2019

Foxf1 +/- mice exhibit defective stellate cell activation and abnormal liver regeneration following CCl4 injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

smoothened signaling pathway

1 reference

9 May 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

lateral mesodermal cell differentiation

1 reference

9 May 2019

The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

mesenchyme migration

1 reference

9 May 2019

Forkhead box F1 is essential for migration of mesenchymal cells and directly induces integrin-beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

lung alveolus development

1 reference

9 May 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

mesoderm development

epithelial tube branching involved in lung morphogenesis

1 reference

9 May 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

negative regulation of inflammatory response

1 reference

9 May 2019

Pulmonary mastocytosis and enhanced lung inflammation in mice heterozygous null for the Foxf1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

embryonic digestive tract development

1 reference

9 May 2019

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

lung lobe morphogenesis

1 reference

9 May 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

positive regulation of transcription by RNA polymerase II

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

Forkhead box F1 is essential for migration of mesenchymal cells and directly induces integrin-beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

Members of the HNF-3/forkhead family of transcription factors exhibit distinct cellular expression patterns in lung and regulate the surfactant protein B promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

Forkhead box F1 is essential for migration of mesenchymal cells and directly induces integrin-beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

The winged helix transcriptional activator HFH-8 is expressed in the mesoderm of the primitive streak stage of mouse embryos and its cellular derivatives

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

epithelial cell differentiation involved in mammary gland alveolus development

1 reference

9 May 2019

Alterations in alveolar epithelium differentiation and vasculogenesis in lungs of LIF/IGF-I double deficient embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

positive regulation of cell-substrate adhesion

1 reference

9 May 2019

Forkhead box F1 is essential for migration of mesenchymal cells and directly induces integrin-beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

transcription by RNA polymerase II

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61080&geneProductId=UniProtKB:Q61080

cell-cell adhesion

1 reference

9 May 2019

The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

trachea development

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

smooth muscle cell differentiation

Hedgehog induction of murine vasculogenesis is mediated by Foxf1 and Bmp4

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

9 May 2019

Hedgehog induction of murine vasculogenesis is mediated by Foxf1 and Bmp4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61080

Fork head domain conserved site 2

has part(s)

1 reference

Fork head domain

1 reference

Fork head domain conserved site1

1 reference