(Q21982746)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61313

Transcription factor AP-2, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

1 reference

14 February 2019

transcription coactivator activity

1 reference

24 April 2018

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

sequence-specific DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

transcription corepressor activity

1 reference

24 April 2018

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

protein dimerization activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

DNA-binding transcription factor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

5 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

transcription coactivator activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

DNA-binding transcription activator activity, RNA polymerase II-specific

RNA polymerase II general transcription initiation factor activity

2 references

10 September 2018

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

7 November 2018

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

cysteine-type endopeptidase inhibitor activity involved in apoptotic process

1 reference

14 February 2019

Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

protein binding

IPI

1 reference

14 February 2019

Cloning and characterization of the mouse AP-2 epsilon gene: a novel family member expressed in the developing olfactory bulb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

RNA polymerase II core promoter sequence-specific DNA binding

IPI

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

24 April 2018

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

RNA polymerase II cis-regulatory region sequence-specific DNA binding

RNA polymerase II core promoter sequence-specific DNA binding

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

transcription corepressor activity

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

RNA polymerase II cis-regulatory region sequence-specific DNA binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

DNA-binding transcription factor activity, RNA polymerase II-specific

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

DNA-binding transcription factor activity, RNA polymerase II-specific

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

cell component

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

6 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

negative regulation of neuron apoptotic process

biological process

1 reference

14 February 2019

The transcription factors AP-2β and AP-2α are required for survival of sympathetic progenitors and differentiated sympathetic neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

forelimb morphogenesis

1 reference

14 February 2019

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

collecting duct development

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

cellular urea homeostasis

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

5 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

sympathetic nervous system development

1 reference

14 February 2019

The transcription factors AP-2β and AP-2α are required for survival of sympathetic progenitors and differentiated sympathetic neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

positive regulation of urine volume

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

glucose homeostasis

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

calcium ion homeostasis

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

distal tubule development

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

kidney development

1 reference

14 February 2019

Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2β

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

regulation of insulin secretion

retina layer formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

phosphate ion homeostasis

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

cellular creatinine homeostasis

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

negative regulation of apoptotic process

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

transcription by RNA polymerase II

1 reference

14 February 2019

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

metanephric nephron development

1 reference

14 February 2019

Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

aorta morphogenesis

1 reference

14 February 2019

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

magnesium ion homeostasis

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

hindlimb morphogenesis

1 reference

14 February 2019

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

1 reference

21 June 2018

response to lithium ion

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61313&geneProductId=UniProtKB:Q61313

regulation of BMP signaling pathway

1 reference

14 February 2019

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

positive regulation of neuron apoptotic process

cellular ammonium homeostasis

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

potassium ion homeostasis

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

positive regulation of cell population proliferation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

renal water homeostasis

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

glucose metabolic process

sensory organ development

1 reference

14 February 2019

Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

regulation of cell differentiation

sodium ion homeostasis

1 reference

14 February 2019

Terminal renal failure in mice lacking transcription factor AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

negative regulation of transcription, DNA-templated

ductus arteriosus closure

1 reference

14 February 2019

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

positive regulation of transcription by RNA polymerase II

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

14 February 2019

Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

negative regulation of cell population proliferation

1 reference

14 February 2019

Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

apoptotic process

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61313

Transcription factor AP-2, C-terminal

has part(s)

1 reference

InterPro Release 71.0