(Q21498784)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9DBL9

Alpha/beta hydrolase fold-1, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

1 reference

14 February 2019

triglyceride lipase activity

1 reference

14 February 2019

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

1-acylglycerol-3-phosphate O-acyltransferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

1 reference

14 February 2019

acyltransferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

1 reference

14 February 2019

protein binding

lysophosphatidic acid acyltransferase activity

IPI

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9DBL9&geneProductId=UniProtKB:Q9DBL9

lysophosphatidic acid acyltransferase activity

ISO

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

carboxylic ester hydrolase activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

cell component

lipid droplet

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9DBL9&geneProductId=UniProtKB:Q9DBL9

6 references

5 June 2018

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9DBL9&geneProductId=UniProtKB:Q9DBL9

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9DBL9&geneProductId=UniProtKB:Q9DBL9

5 June 2018

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9DBL9&geneProductId=UniProtKB:Q9DBL9

5 June 2018

CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9DBL9&geneProductId=UniProtKB:Q9DBL9

5 June 2018

Interactions of Perilipin-5 (Plin5) with Adipose Triglyceride Lipase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9DBL9&geneProductId=UniProtKB:Q9DBL9

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

1 reference

14 February 2019

lipid droplet

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

7 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

Interactions of Perilipin-5 (Plin5) with Adipose Triglyceride Lipase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

positive regulation of lipid catabolic process

biological process

IMP

1 reference

14 February 2019

Regulation of skeletal muscle lipolysis and oxidative metabolism by the co-lipase CGI-58

GOA

curator

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

IMP

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

1 reference

14 February 2019

positive regulation of lipoprotein lipase activity

1 reference

14 February 2019

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

negative regulation of sequestering of triglyceride

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

positive regulation of triglyceride catabolic process

3 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9DBL9&geneProductId=UniProtKB:Q9DBL9

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9DBL9&geneProductId=UniProtKB:Q9DBL9

31 October 2017

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9DBL9&geneProductId=UniProtKB:Q9DBL9

fatty acid metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

1 reference

14 February 2019

phospholipid biosynthetic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

1 reference

14 February 2019

phosphatidic acid biosynthetic process

3 references

CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome

3 references

14 February 2019

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

negative regulation of sequestering of triglyceride

positive regulation of triglyceride catabolic process

ISO

phosphatidic acid biosynthetic process

ISO

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

positive regulation of triglyceride catabolic process

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

lipid homeostasis

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9DBL9

Alpha/beta hydrolase fold-1

has part(s)

1 reference

InterPro Release 71.0