(Q21114583)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q08752

Cyclophilin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q08752

cyclophilin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q08752

Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, protein family

1 reference

Tetratricopeptide repeat-containing domain, protein family

1 reference

Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site, protein family

1 reference

Tetratricopeptide repeat family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

Hsp90 protein binding

1 reference

8 April 2019

A structure-based mutational analysis of cyclophilin 40 identifies key residues in the core tetratricopeptide repeat domain that mediate binding to Hsp90

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

heat shock protein binding

1 reference

8 April 2019

Specific binding of tetratricopeptide repeat proteins to the C-terminal 12-kDa domain of hsp90

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

transcription factor binding

1 reference

8 April 2019

Point mutations in v-Myb disrupt a cyclophilin-catalyzed negative regulatory mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

isomerase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

1 reference

8 April 2019

peptidyl-prolyl cis-trans isomerase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

24 April 2018

24 April 2018

Functional analysis of the Hsp90-associated human peptidyl prolyl cis/trans isomerases FKBP51, FKBP52 and Cyp40

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

24 April 2018

Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

Hsp70 protein binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

1 reference

8 April 2019

ISS

protein binding

3 references

8 April 2019

Identification of cyclophilin-40-interacting proteins reveals potential cellular function of cyclophilin-40

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

8 April 2019

Point mutations in v-Myb disrupt a cyclophilin-catalyzed negative regulatory mechanism

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

8 April 2019

Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

estrogen receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

1 reference

8 April 2019

ISS

cyclosporin A binding

Expression of human cyclophilin-40 and the effect of the His141-->Trp mutation on catalysis and cyclosporin A binding

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

24 April 2018

The structure and complete nucleotide sequence of the human cyclophilin 40 (PPID) gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

24 April 2018

Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

peptidyl-prolyl cis-trans isomerase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

8 April 2019

8 April 2019

Functional analysis of the Hsp90-associated human peptidyl prolyl cis/trans isomerases FKBP51, FKBP52 and Cyp40

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

8 April 2019

Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

cyclosporin A binding

Expression of human cyclophilin-40 and the effect of the His141-->Trp mutation on catalysis and cyclosporin A binding

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

8 April 2019

The structure and complete nucleotide sequence of the human cyclophilin 40 (PPID) gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

8 April 2019

Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

unfolded protein binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

Hsp90 protein binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

3 references

8 April 2019

8 April 2019

Human cyclophilin 40 is a heat shock protein that exhibits altered intracellular localization following heat shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

8 April 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

3 references

8 April 2019

8 April 2019

Human cyclophilin 40 is a heat shock protein that exhibits altered intracellular localization following heat shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

8 April 2019

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

1 reference

8 April 2019

nucleolus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

4 references

10 September 2018

10 September 2018

Human cyclophilin 40 is a heat shock protein that exhibits altered intracellular localization following heat shock

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

10 September 2018

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

mitochondrion

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

chaperone-mediated protein folding

biological process

1 reference

8 April 2019

Functional analysis of the Hsp90-associated human peptidyl prolyl cis/trans isomerases FKBP51, FKBP52 and Cyp40

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

cellular response to UV-A

1 reference

8 April 2019

Cyclophilin 40 alters UVA-induced apoptosis and mitochondrial ROS generation in keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

viral release from host cell

1 reference

8 April 2019

Inhibition of cyclophilins alters lipid trafficking and blocks hepatitis C virus secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

lipid droplet organization

1 reference

8 April 2019

Inhibition of cyclophilins alters lipid trafficking and blocks hepatitis C virus secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Cyclophilin-40 has a cellular role in the aryl hydrocarbon receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

positive regulation of protein secretion

1 reference

8 April 2019

Inhibition of cyclophilins alters lipid trafficking and blocks hepatitis C virus secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

positive regulation of apoptotic process

1 reference

8 April 2019

Cyclophilin 40 alters UVA-induced apoptosis and mitochondrial ROS generation in keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

protein transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

1 reference

8 April 2019

positive regulation of viral genome replication

1 reference

8 April 2019

Multiple cyclophilins involved in different cellular pathways mediate HCV replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

1 reference

8 April 2019

protein-containing complex assembly

1 reference

8 April 2019

Cyclophilin-40 has a cellular role in the aryl hydrocarbon receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

negative regulation of transcription by RNA polymerase II

protein refolding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08752

negative regulation of apoptotic process

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

positive regulation of viral genome replication

positive regulation of protein secretion

regulation of mitochondrial membrane potential

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08752&geneProductId=UniProtKB:Q08752

chaperone-mediated protein folding

protein-containing complex assembly

D08.811.399.325.500.400.300.875

Identifiers

MeSH descriptor ID

D000081406

subject named as

Peptidyl-Prolyl Isomerase F

0 references

MeSH tree code

0 references

D12.776.543.750.705.400.350.875

0 references

D12.776.827.344.300.875

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023