Wikidata

(Q21097342)

English

Parkinsonism associated deglycase

mammalian protein found in Homo sapiens

  • epididymis secretory sperm binding protein Li 67p
  • protein DJ-1
  • protein/nucleic acid deglycase DJ-1
  • maillard deglycase
  • Parkinson disease (autosomal recessive, early onset) 7
  • oncogene DJ1
  • protein deglycase DJ-1
  • PARK7
  • parkinson protein 7
  • Parkinson disease protein 7
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
18 references
retrieved
9 May 2019
stated in
DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
Regulation of the VHL/HIF-1 pathway by DJ-1
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
DJ-1 binds to mitochondrial complex I and maintains its activity
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
DJ-1 enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
Nuclear translocation of DJ-1 during oxidative stress-induced neuronal cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosis
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADD
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
DJ-1 enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
DJ-1 cooperates with PYCR1 in cell protection against oxidative stress
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
retrieved
9 May 2019
stated in
Increased interaction between DJ-1 and the Mi-2/ nucleosome remodelling and deacetylase complex during cellular stress
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IPI
cell component
cytoplasm
determination method or standard
IDA
IEA
6 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IEA
retrieved
9 May 2019
stated in
Mitochondrial localization of DJ-1 leads to enhanced neuroprotection
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
DJ-1 binds to mitochondrial complex I and maintains its activity
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
cytosol
determination method or standard
IDA
IEA
IMP
7 references
retrieved
17 October 2017
stated in
DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADD
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IMP
retrieved
17 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IEA
retrieved
17 October 2017
stated in
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
Nuclear translocation of DJ-1 during oxidative stress-induced neuronal cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
mitochondrion
determination method or standard
IDA
IEA
IMP
9 references
retrieved
9 May 2019
stated in
DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADD
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IMP
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IEA
retrieved
9 May 2019
stated in
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Mitochondrial localization of DJ-1 leads to enhanced neuroprotection
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
DJ-1 binds to mitochondrial complex I and maintains its activity
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
DJ-1 cooperates with PYCR1 in cell protection against oxidative stress
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
nucleus
determination method or standard
IDA
IEA
12 references
retrieved
17 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IEA
retrieved
17 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IEA
retrieved
17 October 2017
stated in
DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
Proteomic characterization of the human sperm nucleus
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
Mitochondrial localization of DJ-1 leads to enhanced neuroprotection
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
Nuclear translocation of DJ-1 during oxidative stress-induced neuronal cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
DJ-1 binds to mitochondrial complex I and maintains its activity
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
extracellular exosome
determination method or standard
IDA
5 references
retrieved
17 October 2017
stated in
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
17 October 2017
stated in
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99497&geneProductId=UniProtKB:Q99497
determination method or standard
IDA
nucleus
determination method or standard
HDA
IBA
IDA
IEA
13 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IEA
retrieved
9 May 2019
stated in
DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Mitochondrial localization of DJ-1 leads to enhanced neuroprotection
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
DJ-1 binds to mitochondrial complex I and maintains its activity
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Nuclear translocation of DJ-1 during oxidative stress-induced neuronal cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IBA
retrieved
9 May 2019
stated in
Proteomic characterization of the human sperm nucleus
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
HDA
cytosol
determination method or standard
IBA
IDA
IEA
IMP
8 references
retrieved
9 May 2019
stated in
DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADD
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IMP
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IEA
retrieved
9 May 2019
stated in
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Nuclear translocation of DJ-1 during oxidative stress-induced neuronal cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IBA
biological process
negative regulation of protein binding
determination method or standard
IDA
IGI
IMP
6 references
retrieved
9 May 2019
stated in
DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADD
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IMP
retrieved
9 May 2019
stated in
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IGI
retrieved
9 May 2019
stated in
DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Regulation of the VHL/HIF-1 pathway by DJ-1
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
protein stabilization
determination method or standard
IDA
IEA
IMP
5 references
retrieved
9 May 2019
stated in
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IMP
retrieved
9 May 2019
stated in
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
GOA
curator
UniProt
UniProt protein ID
Q99497
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IMP
retrieved
9 May 2019
stated in
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IMP
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IEA
retrieved
9 May 2019
stated in
DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosis
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
cellular response to oxidative stress
determination method or standard
IDA
IEA
IMP
6 references
retrieved
9 May 2019
stated in
Regulation of the VHL/HIF-1 pathway by DJ-1
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IMP
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IEA
retrieved
9 May 2019
stated in
DJ-1 Cleavage by Matrix Metalloproteinase 3 Mediates Oxidative Stress-Induced Dopaminergic Cell Death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
retrieved
9 May 2019
stated in
Nuclear translocation of DJ-1 during oxidative stress-induced neuronal cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA
positive regulation of transcription by RNA polymerase II
determination method or standard
IDA
IGI
IEA
IMP
7 references
retrieved
9 May 2019
stated in
DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IMP
retrieved
9 May 2019
stated in
DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IMP
retrieved
9 May 2019
stated in
Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IMP
retrieved
9 May 2019
stated in
The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IGI
retrieved
9 May 2019
stated in
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IGI
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IEA
retrieved
9 May 2019
stated in
DJ-1 enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99497
determination method or standard
IDA

Identifiers

MeSH descriptor ID
D000071617
subject named as
Protein Deglycase DJ-1
0 references
MeSH tree code
D08.811.277.785
0 references
D12.776.705.875
0 references
PDB structure ID
 
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21097342&oldid=2251910382"