(Q14914534)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

3 references

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

24 April 2018

Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

heparin binding

Characterization of sequences within heparin-binding EGF-like growth factor that mediate interaction with heparin

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

protein tyrosine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

1 reference

10 September 2018

phosphatidylinositol-4,5-bisphosphate 3-kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

1 reference

10 September 2018

epidermal growth factor receptor binding

Importance of the major extracellular domain of CD9 and the epidermal growth factor (EGF)-like domain of heparin-binding EGF-like growth factor for up-regulation of binding and activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

growth factor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

heparin binding

Characterization of sequences within heparin-binding EGF-like growth factor that mediate interaction with heparin

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

endocytic vesicle membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

1 reference

8 April 2019

integral component of membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

1 reference

8 April 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

1 reference

8 April 2019

clathrin-coated endocytic vesicle membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

1 reference

8 April 2019

integral component of plasma membrane

Ectodomain shedding of membrane-anchored heparin-binding EGF like growth factor and subcellular localization of the C-terminal fragment in the cell cycle

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

extracellular space

Ectodomain shedding of membrane-anchored heparin-binding EGF like growth factor and subcellular localization of the C-terminal fragment in the cell cycle

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

24 April 2018

TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

extracellular space

Ectodomain shedding of membrane-anchored heparin-binding EGF like growth factor and subcellular localization of the C-terminal fragment in the cell cycle

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

integral component of plasma membrane

Ectodomain shedding of membrane-anchored heparin-binding EGF like growth factor and subcellular localization of the C-terminal fragment in the cell cycle

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

clathrin-coated vesicle membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

1 reference

8 April 2019

positive regulation of keratinocyte migration

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

cell chemotaxis

1 reference

8 April 2019

CAP37 activation of PKC promotes human corneal epithelial cell chemotaxis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

MAPK cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

1 reference

8 April 2019

wound healing, spreading of epidermal cells

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

positive regulation of cell migration

1 reference

8 April 2019

EGF receptor transactivation and PI3-kinase mediate stimulation of ERK by alpha(2A)-adrenoreceptor in intestinal epithelial cells: a role in wound healing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

positive regulation of cell growth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

muscle organ development

1 reference

8 April 2019

Structural organization and chromosomal assignment of the gene encoding the human heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

positive regulation of smooth muscle cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

regulation of heart contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

negative regulation of elastin biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

cell migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

positive regulation of wound healing

1 reference

8 April 2019

EGF receptor transactivation and PI3-kinase mediate stimulation of ERK by alpha(2A)-adrenoreceptor in intestinal epithelial cells: a role in wound healing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

epidermal growth factor receptor signaling pathway

EGF receptor transactivation and PI3-kinase mediate stimulation of ERK by alpha(2A)-adrenoreceptor in intestinal epithelial cells: a role in wound healing

2 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

ERBB2 signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

1 reference

8 April 2019

phosphatidylinositol phosphate biosynthetic process

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

peptidyl-tyrosine phosphorylation

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

regulation of cell motility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

1 reference

8 April 2019

positive regulation of peptidyl-tyrosine phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

epidermal growth factor receptor signaling pathway

EGF receptor transactivation and PI3-kinase mediate stimulation of ERK by alpha(2A)-adrenoreceptor in intestinal epithelial cells: a role in wound healing

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99075&geneProductId=UniProtKB:Q99075

epidermal growth factor receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

4 references

8 April 2019

8 April 2019

EGF receptor transactivation and PI3-kinase mediate stimulation of ERK by alpha(2A)-adrenoreceptor in intestinal epithelial cells: a role in wound healing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

negative regulation of epidermal growth factor receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

1 reference

8 April 2019

membrane organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99075

1 reference

8 April 2019

Gene Atlas image

PBB GE HBEGF 38037 at fs.png
732 × 530; 10 KB

0 references

has part(s)

EGF-like, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99075

EGF-like domain

1 reference

InterPro Release 71.0