Zingerone was proven to possess many pharmacological functions including hepatoprotective, antipa... more Zingerone was proven to possess many pharmacological functions including hepatoprotective, antiparasitic, antiflarial, antimicrobial, antidiabetic and radio protective properties. The aim for this study was to evaluate the antioxidant potential of zingerone against high fructose diet induced NASH. A total of 24 rats were used in this in vivo study. The rats were divided into four groups (n=6) and treated as follows for 8 weeks: Group 1 (CON): Rats received normal standard pellet diet with water, Group 2 (ZIN): Rats received normal pellet diet and zingerone (100 mg/kg body wt /day), Group 3 (HFD): Rats received high fructose diet (40% of fructose and rodent chow with drinking water (25% fructose). Group 4 (HFD+ZIN): Rats received high fructose diet and zingerone (100 mg/kg body wt /day). DPPH radical scavenging activity and total phenolic content assay were done to determine antioxidant potential of zingerone as for the preventive effect of NASH. The results indicated that the zinger...
Zingerone was proven to possess many pharmacological functions including hepatoprotective, antipa... more Zingerone was proven to possess many pharmacological functions including hepatoprotective, antiparasitic, antiflarial, antimicrobial, antidiabetic and radio protective properties. The aim for this study was to evaluate the antioxidant potential of zingerone against high fructose diet induced NASH. A total of 24 rats were used in this in vivo study. The rats were divided into four groups (n=6) and treated as follows for 8 weeks: Group 1 (CON): Rats received normal standard pellet diet with water, Group 2 (ZIN): Rats received normal pellet diet and zingerone (100 mg/kg body wt /day), Group 3 (HFD): Rats received high fructose diet (40% of fructose and rodent chow with drinking water (25% fructose). Group 4 (HFD+ZIN): Rats received high fructose diet and zingerone (100 mg/kg body wt /day). DPPH radical scavenging activity and total phenolic content assay were done to determine antioxidant potential of zingerone as for the preventive effect of NASH. The results indicated that the zinger...
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